AutismKB 2.0

Annotation Detail for CDC25B


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Basic Information Top
Gene Symbol:CDC25B ( - )
Gene Full Name: cell division cycle 25 homolog B (S. pombe)
Band: 20p13
Quick LinksEntrez ID:994; OMIM: 116949; Uniprot ID:MPIP2_HUMAN; ENSEMBL ID: ENSG00000101224; HGNC ID: 1726
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst5 / 6231980
fetus26 / 56401246
neonate6 / 31097192
infant3 / 23620127
juvenile7 / 55556125
adult166 / 193912185
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor13 / 94178138
cervical tumor4 / 34366116
chondrosarcoma10 / 82823120
colorectal tumor16 / 114246140
esophageal tumor0 / 172900 
gastrointestinal tumor16 / 119369134
germ cell tumor31 / 263845117
glioma26 / 106883243
head and neck tumor12 / 13630288
kidney tumor6 / 6895987
leukemia12 / 95842125
liver tumor10 / 96359103
lung tumor37 / 103127358
lymphoma4 / 7175555
non-neoplasia2 / 9725020
normal216 / 336030764
ovarian tumor10 / 76682130
pancreatic tumor20 / 104616191
primitive neuroectodermal tumor of the CNS27 / 125680214
prostate cancer14 / 102680136
retinoblastoma5 / 46356107
skin tumor17 / 124949136
soft tissue/muscle tissue tumor22 / 125191175
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland3 / 3319790
ascites8 / 40015199
bladder0 / 297570 
blood15 / 123478121
bone4 / 7165555
bone marrow0 / 488010 
brain120 / 1100989108
cervix4 / 4817183
connective tissue12 / 14925580
ear0 / 162120 
embryonic tissue9 / 21572241
esophagus1 / 2020949
eye9 / 21105442
heart5 / 8962655
intestine23 / 23447298
kidney12 / 21177756
larynx0 / 241450 
liver13 / 20774362
lung49 / 336974145
lymph1 / 4427022
lymph node12 / 91610130
mammary gland17 / 153271110
mouth3 / 6705244
muscle8 / 10771574
nerve1 / 1576863
ovary13 / 102051127
pancreas25 / 214812116
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta28 / 28082599
prostate15 / 18934579
salivary gland8 / 20155396
skin28 / 210574132
spleen2 / 5395237
stomach8 / 9661982
testis25 / 33044275
thymus26 / 81131320
thyroid1 / 4747321
tonsil2 / 16999117
trachea2 / 5241338
umbilical cord0 / 136800 
uterus24 / 232878103
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201853_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts206
Adipocyte12.6
AdrenalCortex7.95
Adrenalgland5.65
Amygdala14.2
Appendix6.6
AtrioventricularNode4.9
BDCA4+_DentriticCells133.3
Bonemarrow28.7
BronchialEpithelialCells54.85
CD105+_Endothelial70.6
CD14+_Monocytes9.55
CD19+_BCells(neg._sel.)280.9
CD33+_Myeloid75.55
CD34+95.65
CD4+_Tcells1266
CD56+_NKCells496.05
CD71+_EarlyErythroid266.65
CD8+_Tcells1080.6
CardiacMyocytes222.3
Caudatenucleus20.3
Cerebellum47.15
CerebellumPeduncles67.95
CiliaryGanglion6.7
CingulateCortex11.65
Colorectaladenocarcinoma343.1
DorsalRootGanglion5.45
FetalThyroid17.3
Fetalbrain7.6
Fetalliver9.5
Fetallung71.15
GlobusPallidus5
Heart13.8
Hypothalamus32.7
Kidney5.7
Leukemia_chronicMyelogenousK-56210.95
Leukemia_promyelocytic-HL-6027.45
Leukemialymphoblastic(MOLT-4)341.5
Liver9.45
Lung106.75
Lymphnode42.2
Lymphoma_burkitts(Daudi)138.95
Lymphoma_burkitts(Raji)79.4
MedullaOblongata11.15
OccipitalLobe14.95
OlfactoryBulb20.5
Ovary5.15
Pancreas10.05
PancreaticIslet9.85
ParietalLobe8.25
Pituitary15.6
Placenta19.5
Pons11.6
PrefrontalCortex37.15
Prostate12.05
Salivarygland4.5
SkeletalMuscle7.8
Skin7.2
SmoothMuscle66
Spinalcord13.5
SubthalamicNucleus8.05
SuperiorCervicalGanglion8
TemporalLobe8.35
Testis6.8
TestisGermCell6.65
TestisIntersitial5.3
TestisLeydigCell5.65
TestisSeminiferousTubule6.65
Thalamus11
Thymus177.15
Thyroid19.45
Tongue7.55
Tonsil30.55
Trachea6.35
TrigeminalGanglion8.05
Uterus38.1
UterusCorpus6.2
WholeBlood117.8
Wholebrain13.25
colon9.2
pineal_day20.34
pineal_night26.82
retina18.125
small_intestine23.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14354_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.68 ± 0.74
Basal Forebrain3.24 ± 0.71
Basal Part of Pons3.06 ± 0.47
Cerebellar Cortex3.91 ± 0.46
Cerebellar Nuclei3.5 ± 0.71
Claustrum3.58 ± 0.76
Epithalamus3.19 ± 0.63
Frontal Lobe3.29 ± 0.7
Globus Pallidus2.65 ± 0.71
Hypothalamus3.26 ± 0.73
Insula3.37 ± 0.64
Limbic Lobe3.23 ± 0.75
Mesencephalon3.39 ± 0.69
Myelencephalon3.33 ± 0.66
Occipital Lobe3.05 ± 0.86
Parietal Lobe3.23 ± 0.71
Pontine Tegmentum3.42 ± 0.76
Striatum3.59 ± 0.74
Subthalamus3.35 ± 0.85
Temporal Lobe3.41 ± 0.59
Thalamus3.18 ± 0.61
White Matter3.17 ± 0.8
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cdc25bCBCerebellum10.01
13.32
Cdc25bCTXCerebral cortex21.18
12.94
Cdc25bHIPHippocampal region15.5
19.61
Cdc25bHPFHippocampal formation20.28
19.21
Cdc25bHYHypothalamus1.93
1.39
Cdc25bLSXLateral septal complex3.05
2.06
Cdc25bMBMidbrain4.78
3.98
Cdc25bMYMedulla8.99
8.11
Cdc25bOLFOlfactory bulb7.07
4.49
Cdc25bPPons4.92
4.08
Cdc25bPALPallidum1.43
1.21
Cdc25bRHPRetrohippocampal region28.88
20.06
Cdc25bsAMYStriatum-like amygdalar nuclei1.2
0.78
Cdc25bSTRStriatum3.66
2.63
Cdc25bSTRdStriatum dorsal region3.17
2.36
Cdc25bSTRvStriatum ventral region6.41
4.08
Cdc25bTHThalamus6.44
4.51
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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