AutismKB 2.0

Annotation Detail for DLEC1


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Basic Information Top
Gene Symbol:DLEC1 ( DLC1,F56 )
Gene Full Name: deleted in lung and esophageal cancer 1
Band: 3p22.2
Quick LinksEntrez ID:9940; OMIM: 604050; Uniprot ID:DLEC1_HUMAN; ENSEMBL ID: ENSG00000008226; HGNC ID: 2899
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus3 / 5640125
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult18 / 19391219
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor0 / 2638450 
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal21 / 33603076
ovarian tumor1 / 7668213
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain3 / 11009892
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung13 / 33697438
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary1 / 1020519
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach1 / 9661910
testis8 / 33044224
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 207896_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.3
Adipocyte6.75
AdrenalCortex8.3
Adrenalgland5.65
Amygdala5.85
Appendix7.15
AtrioventricularNode12.6
BDCA4+_DentriticCells6.75
Bonemarrow6.5
BronchialEpithelialCells6.05
CD105+_Endothelial6.5
CD14+_Monocytes7.2
CD19+_BCells(neg._sel.)10.1
CD33+_Myeloid8.15
CD34+8.35
CD4+_Tcells7
CD56+_NKCells8.7
CD71+_EarlyErythroid7.1
CD8+_Tcells6.45
CardiacMyocytes8.55
Caudatenucleus5.8
Cerebellum5.6
CerebellumPeduncles7.7
CiliaryGanglion5.55
CingulateCortex6.65
Colorectaladenocarcinoma6.4
DorsalRootGanglion9.85
FetalThyroid6.3
Fetalbrain6.3
Fetalliver5.65
Fetallung5.45
GlobusPallidus7.2
Heart9.05
Hypothalamus6.85
Kidney5.65
Leukemia_chronicMyelogenousK-5625.8
Leukemia_promyelocytic-HL-605.55
Leukemialymphoblastic(MOLT-4)5.1
Liver9
Lung6.85
Lymphnode5.45
Lymphoma_burkitts(Daudi)8.1
Lymphoma_burkitts(Raji)9.65
MedullaOblongata5.85
OccipitalLobe5.8
OlfactoryBulb7.45
Ovary7.95
Pancreas5.25
PancreaticIslet6.8
ParietalLobe7.2
Pituitary8.65
Placenta6.4
Pons17.85
PrefrontalCortex7.9
Prostate6.9
Salivarygland9.05
SkeletalMuscle13.75
Skin12.85
SmoothMuscle6.85
Spinalcord7.25
SubthalamicNucleus7.95
SuperiorCervicalGanglion8.65
TemporalLobe6
Testis7.15
TestisGermCell10.65
TestisIntersitial9.6
TestisLeydigCell9.7
TestisSeminiferousTubule8.9
Thalamus6.85
Thymus4.85
Thyroid7.3
Tongue6.6
Tonsil6.3
Trachea8.25
TrigeminalGanglion9.15
Uterus4.95
UterusCorpus16
WholeBlood6.7
Wholebrain4.95
colon6.45
pineal_day9.42
pineal_night7.58
retina7.625
small_intestine6.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_232_PI416408490
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.11 ± 1.02
Basal Forebrain1.65 ± 0.2
Basal Part of Pons1.33 ± 0.34
Cerebellar Cortex1.5 ± 0.74
Cerebellar Nuclei1.94 ± 0.72
Claustrum2.64 ± 0.88
Epithalamus1.69 ± 0.73
Frontal Lobe1.5 ± 0.66
Globus Pallidus2.23 ± 0.27
Hypothalamus2.02 ± 1.28
Insula1.59 ± 0.54
Limbic Lobe1.66 ± 0.61
Mesencephalon1.81 ± 0.66
Myelencephalon1.7 ± 0.64
Occipital Lobe1.71 ± 0.54
Parietal Lobe1.74 ± 0.79
Pontine Tegmentum1.69 ± 0.65
Striatum1.89 ± 0.59
Subthalamus2.04 ± 0.83
Temporal Lobe1.58 ± 0.6
Thalamus1.63 ± 0.54
White Matter2.07 ± 0.21
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018