AutismKB 2.0

Annotation Detail for EXOG


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Basic Information Top
Gene Symbol:EXOG ( ENDOGL1,ENDOGL2,ENGL,ENGL-a,ENGL-b,ENGLA,ENGLB,MGC125944,MGC125945 )
Gene Full Name: endo/exonuclease (5'-3'), endonuclease G-like
Band: 3p22.2
Quick LinksEntrez ID:9941; OMIM: 604051; Uniprot ID:EXOG_HUMAN; ENSEMBL ID: ENSG00000157036; HGNC ID: 3347
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst1 / 6231916
fetus17 / 56401230
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult49 / 193912125
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor9 / 11424678
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor8 / 26384530
glioma0 / 1068830 
head and neck tumor7 / 13630251
kidney tumor3 / 6895943
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma5 / 7175569
non-neoplasia1 / 9725010
normal70 / 336030720
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone0 / 716550 
bone marrow1 / 4880120
brain29 / 110098926
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus0 / 202090 
eye2 / 2110549
heart5 / 8962655
intestine11 / 23447246
kidney6 / 21177728
larynx2 / 2414582
liver0 / 2077430 
lung5 / 33697414
lymph0 / 442700 
lymph node1 / 9161010
mammary gland0 / 1532710 
mouth2 / 6705229
muscle1 / 1077159
nerve2 / 15768126
ovary0 / 1020510 
pancreas2 / 2148129
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate5 / 18934526
salivary gland0 / 201550 
skin0 / 2105740 
spleen3 / 5395255
stomach0 / 966190 
testis14 / 33044242
thymus1 / 8113112
thyroid3 / 4747363
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205521_at
Cell line Expression level Expression bar
721_B_lymphoblasts15.5
Adipocyte9.55
AdrenalCortex9.75
Adrenalgland9.25
Amygdala10.3
Appendix9.7
AtrioventricularNode7.15
BDCA4+_DentriticCells10.8
Bonemarrow9.75
BronchialEpithelialCells9.65
CD105+_Endothelial8.95
CD14+_Monocytes10.05
CD19+_BCells(neg._sel.)7.3
CD33+_Myeloid10.75
CD34+8.05
CD4+_Tcells11.85
CD56+_NKCells10.85
CD71+_EarlyErythroid8.6
CD8+_Tcells9.9
CardiacMyocytes11.7
Caudatenucleus8.6
Cerebellum19.45
CerebellumPeduncles14.2
CiliaryGanglion6.55
CingulateCortex10.2
Colorectaladenocarcinoma9.9
DorsalRootGanglion7.2
FetalThyroid9.2
Fetalbrain9.5
Fetalliver8.3
Fetallung7.7
GlobusPallidus6.9
Heart12.9
Hypothalamus18.35
Kidney7.9
Leukemia_chronicMyelogenousK-5628.55
Leukemia_promyelocytic-HL-6011.05
Leukemialymphoblastic(MOLT-4)12.05
Liver12.55
Lung10.75
Lymphnode10.55
Lymphoma_burkitts(Daudi)12.45
Lymphoma_burkitts(Raji)17.55
MedullaOblongata8.95
OccipitalLobe8.65
OlfactoryBulb7.5
Ovary6.4
Pancreas7.35
PancreaticIslet13.1
ParietalLobe10
Pituitary11.9
Placenta8.3
Pons9.1
PrefrontalCortex12.2
Prostate11.3
Salivarygland7.5
SkeletalMuscle10.65
Skin7.25
SmoothMuscle10.9
Spinalcord10.1
SubthalamicNucleus8.6
SuperiorCervicalGanglion11.25
TemporalLobe8.65
Testis11.8
TestisGermCell8.9
TestisIntersitial8.05
TestisLeydigCell9.45
TestisSeminiferousTubule8.3
Thalamus9.75
Thymus8.75
Thyroid12.1
Tongue9.3
Tonsil9.3
Trachea8.05
TrigeminalGanglion9.3
Uterus8
UterusCorpus8.55
WholeBlood12.15
Wholebrain15.3
colon9.6
pineal_day13.22
pineal_night11.78
retina11.475
small_intestine8.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P250714
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.27 ± 0.46
Basal Forebrain5 ± 0.7
Basal Part of Pons4.81 ± 0.33
Cerebellar Cortex5.14 ± 0.28
Cerebellar Nuclei5.12 ± 0.61
Claustrum4.43 ± 0.51
Epithalamus5.14 ± 0.45
Frontal Lobe4.76 ± 0.44
Globus Pallidus4.88 ± 0.42
Hypothalamus4.82 ± 0.51
Insula4.96 ± 0.29
Limbic Lobe4.87 ± 0.41
Mesencephalon5.02 ± 0.39
Myelencephalon4.87 ± 0.48
Occipital Lobe5.43 ± 0.36
Parietal Lobe5.02 ± 0.37
Pontine Tegmentum4.95 ± 0.5
Striatum5.07 ± 0.38
Subthalamus4.83 ± 0.48
Temporal Lobe4.93 ± 0.41
Thalamus4.85 ± 0.34
White Matter5.32 ± 0.43
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Endogl1CBCerebellum6.23
10.19
Endogl1CTXCerebral cortex13.26
8.89
Endogl1HIPHippocampal region6.83
6.5
Endogl1HPFHippocampal formation7.97
6.56
Endogl1HYHypothalamus5.78
3.86
Endogl1LSXLateral septal complex3.41
2.06
Endogl1MBMidbrain8.52
7.62
Endogl1MYMedulla19.12
21.59
Endogl1OLFOlfactory bulb11.23
8.4
Endogl1PPons13.5
13.34
Endogl1PALPallidum6.3
5.06
Endogl1RHPRetrohippocampal region9.92
6.75
Endogl1sAMYStriatum-like amygdalar nuclei2.28
1.55
Endogl1STRStriatum2.86
1.83
Endogl1STRdStriatum dorsal region2.89
1.89
Endogl1STRvStriatum ventral region3.08
1.86
Endogl1THThalamus11.3
8.28
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00064603 13 76 88 CYTNHALSYDQAK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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