AutismKB 2.0

Annotation Detail for CRYZL1


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Basic Information Top
Gene Symbol:CRYZL1 ( 4P11,QOH-1 )
Gene Full Name: crystallin, zeta (quinone reductase)-like 1
Band: 21q22.11
Quick LinksEntrez ID:9946; OMIM: 603920; Uniprot ID:QORL1_HUMAN; ENSEMBL ID: ENSG00000205758; HGNC ID: 2420
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst1 / 6231916
fetus28 / 56401249
neonate0 / 310970 
infant2 / 2362084
juvenile0 / 555560 
adult80 / 193912141
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor1 / 3436629
chondrosarcoma6 / 8282372
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor6 / 26384522
glioma2 / 10688318
head and neck tumor5 / 13630236
kidney tumor3 / 6895943
leukemia2 / 9584220
liver tumor4 / 9635941
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal140 / 336030741
ovarian tumor3 / 7668239
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer6 / 10268058
retinoblastoma3 / 4635664
skin tumor3 / 12494924
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites1 / 4001524
bladder1 / 2975733
blood1 / 1234788
bone2 / 7165527
bone marrow4 / 4880181
brain40 / 110098936
cervix1 / 4817120
connective tissue5 / 14925533
ear1 / 1621261
embryonic tissue9 / 21572241
esophagus0 / 202090 
eye11 / 21105452
heart8 / 8962689
intestine0 / 2344720 
kidney7 / 21177733
larynx1 / 2414541
liver7 / 20774333
lung10 / 33697429
lymph0 / 442700 
lymph node4 / 9161043
mammary gland5 / 15327132
mouth1 / 6705214
muscle0 / 1077150 
nerve0 / 157680 
ovary4 / 10205139
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx6 / 41328145
pituitary gland2 / 16585120
placenta6 / 28082521
prostate14 / 18934573
salivary gland0 / 201550 
skin3 / 21057414
spleen1 / 5395218
stomach2 / 9661920
testis28 / 33044284
thymus6 / 8113173
thyroid1 / 4747321
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus9 / 23287838
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219767_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts14.1
Adipocyte11.95
AdrenalCortex10.8
Adrenalgland9.45
Amygdala41.25
Appendix12.7
AtrioventricularNode9.45
BDCA4+_DentriticCells18.25
Bonemarrow11.6
BronchialEpithelialCells12.25
CD105+_Endothelial9.5
CD14+_Monocytes11.55
CD19+_BCells(neg._sel.)15.8
CD33+_Myeloid12.95
CD34+19.6
CD4+_Tcells18.45
CD56+_NKCells11.65
CD71+_EarlyErythroid12.8
CD8+_Tcells30.05
CardiacMyocytes15.15
Caudatenucleus21.65
Cerebellum9.15
CerebellumPeduncles13.5
CiliaryGanglion8.45
CingulateCortex22.75
Colorectaladenocarcinoma9.8
DorsalRootGanglion9.2
FetalThyroid12.35
Fetalbrain16.5
Fetalliver9.65
Fetallung9.65
GlobusPallidus8.65
Heart14.85
Hypothalamus51.3
Kidney9.65
Leukemia_chronicMyelogenousK-56217.2
Leukemia_promyelocytic-HL-608.95
Leukemialymphoblastic(MOLT-4)19.25
Liver13
Lung7.45
Lymphnode11.75
Lymphoma_burkitts(Daudi)14.15
Lymphoma_burkitts(Raji)13.15
MedullaOblongata25.1
OccipitalLobe18.9
OlfactoryBulb14.25
Ovary7.75
Pancreas9
PancreaticIslet11
ParietalLobe12.65
Pituitary14.2
Placenta13.2
Pons13.4
PrefrontalCortex54.4
Prostate12.5
Salivarygland10.15
SkeletalMuscle14.7
Skin7.35
SmoothMuscle13.65
Spinalcord13.25
SubthalamicNucleus13.55
SuperiorCervicalGanglion14.15
TemporalLobe11
Testis12.35
TestisGermCell26.75
TestisIntersitial29.15
TestisLeydigCell25.15
TestisSeminiferousTubule25.95
Thalamus26.55
Thymus11.35
Thyroid16.55
Tongue11.35
Tonsil10.5
Trachea9.4
TrigeminalGanglion12.05
Uterus15.05
UterusCorpus11
WholeBlood11.8
Wholebrain13.95
colon22.55
pineal_day19.8
pineal_night20.68
retina28.025
small_intestine12.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_853_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.03 ± 0.23
Basal Forebrain7.95 ± 0.15
Basal Part of Pons7.65 ± 0.17
Cerebellar Cortex7.86 ± 0.21
Cerebellar Nuclei7.75 ± 0.18
Claustrum7.88 ± 0.29
Epithalamus8.33 ± 0.24
Frontal Lobe7.91 ± 0.28
Globus Pallidus8.21 ± 0.15
Hypothalamus8 ± 0.28
Insula7.94 ± 0.24
Limbic Lobe7.86 ± 0.24
Mesencephalon8 ± 0.29
Myelencephalon7.84 ± 0.28
Occipital Lobe7.66 ± 0.24
Parietal Lobe7.84 ± 0.24
Pontine Tegmentum7.89 ± 0.25
Striatum7.79 ± 0.25
Subthalamus8.15 ± 0.17
Temporal Lobe7.92 ± 0.23
Thalamus7.71 ± 0.24
White Matter8.74 ± 0.2
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cryzl1CBCerebellum2.82
2.49
Cryzl1CTXCerebral cortex2.2
1.41
Cryzl1HIPHippocampal region15.83
8.63
Cryzl1HPFHippocampal formation10.35
5.52
Cryzl1HYHypothalamus1.29
0.72
Cryzl1LSXLateral septal complex1.36
0.7
Cryzl1MBMidbrain0.75
0.52
Cryzl1MYMedulla1.7
1.25
Cryzl1OLFOlfactory bulb7.39
4.9
Cryzl1PPons1.03
0.75
Cryzl1PALPallidum1.84
1.3
Cryzl1RHPRetrohippocampal region3.05
1.95
Cryzl1sAMYStriatum-like amygdalar nuclei1
0.53
Cryzl1STRStriatum0.93
0.57
Cryzl1STRdStriatum dorsal region0.37
0.31
Cryzl1STRvStriatum ventral region2.69
1.33
Cryzl1THThalamus0.45
0.24
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00064389 15 132 146 AYTALHYLSHLSPGK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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