AutismKB 2.0

Annotation Detail for HS3ST1


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Basic Information Top
Gene Symbol:HS3ST1 ( 3OST,3OST1 )
Gene Full Name: heparan sulfate (glucosamine) 3-O-sulfotransferase 1
Band: 4p15.33
Quick LinksEntrez ID:9957; OMIM: 603244; Uniprot ID:HS3S1_HUMAN; ENSEMBL ID: ENSG00000002587; HGNC ID: 5194
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus10 / 56401217
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult21 / 193912110
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor1 / 2638453
glioma8 / 10688374
head and neck tumor3 / 13630222
kidney tumor0 / 689590 
leukemia3 / 9584231
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal58 / 336030717
ovarian tumor7 / 7668291
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites1 / 4001524
bladder1 / 2975733
blood0 / 1234780 
bone2 / 7165527
bone marrow0 / 488010 
brain30 / 110098927
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye6 / 21105428
heart1 / 8962611
intestine10 / 23447242
kidney8 / 21177737
larynx0 / 241450 
liver1 / 2077434
lung20 / 33697459
lymph0 / 442700 
lymph node1 / 9161010
mammary gland1 / 1532716
mouth1 / 6705214
muscle0 / 1077150 
nerve0 / 157680 
ovary8 / 10205178
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx3 / 4132872
pituitary gland0 / 165850 
placenta1 / 2808253
prostate2 / 18934510
salivary gland0 / 201550 
skin0 / 2105740 
spleen2 / 5395237
stomach1 / 9661910
testis2 / 3304426
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205465_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.4
Adipocyte4.55
AdrenalCortex4.9
Adrenalgland3.85
Amygdala4.7
Appendix4.55
AtrioventricularNode3.45
BDCA4+_DentriticCells4.95
Bonemarrow4.4
BronchialEpithelialCells4.5
CD105+_Endothelial4.5
CD14+_Monocytes4.75
CD19+_BCells(neg._sel.)4.85
CD33+_Myeloid5.65
CD34+5.75
CD4+_Tcells4.85
CD56+_NKCells5.2
CD71+_EarlyErythroid4.25
CD8+_Tcells4.3
CardiacMyocytes5.75
Caudatenucleus4.1
Cerebellum3.65
CerebellumPeduncles5.35
CiliaryGanglion3.3
CingulateCortex4.65
Colorectaladenocarcinoma4.55
DorsalRootGanglion3.5
FetalThyroid4.4
Fetalbrain4.5
Fetalliver3.9
Fetallung3.75
GlobusPallidus3.3
Heart5.75
Hypothalamus4.95
Kidney3.7
Leukemia_chronicMyelogenousK-5624.1
Leukemia_promyelocytic-HL-604.05
Leukemialymphoblastic(MOLT-4)3.65
Liver6.05
Lung5
Lymphnode3.85
Lymphoma_burkitts(Daudi)5.8
Lymphoma_burkitts(Raji)6.3
MedullaOblongata4.1
OccipitalLobe4.05
OlfactoryBulb3.55
Ovary2.95
Pancreas3.65
PancreaticIslet4.8
ParietalLobe4.8
Pituitary5.3
Placenta4.7
Pons4.35
PrefrontalCortex5.6
Prostate5.35
Salivarygland3.6
SkeletalMuscle5.55
Skin3.5
SmoothMuscle5.15
Spinalcord4.85
SubthalamicNucleus4.15
SuperiorCervicalGanglion5.15
TemporalLobe4.15
Testis3.9
TestisGermCell3.75
TestisIntersitial3.8
TestisLeydigCell4.5
TestisSeminiferousTubule3.9
Thalamus4.65
Thymus3.55
Thyroid5.55
Tongue4.5
Tonsil4.4
Trachea3.8
TrigeminalGanglion4.45
Uterus3.65
UterusCorpus4.05
WholeBlood4.9
Wholebrain3.85
colon4.5
pineal_day5.56
pineal_night5.48
retina5.375
small_intestine4.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_10179_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.25 ± 0.88
Basal Forebrain3.96 ± 0.44
Basal Part of Pons3.87 ± 0.77
Cerebellar Cortex4.13 ± 0.54
Cerebellar Nuclei4.09 ± 0.79
Claustrum4.45 ± 0.77
Epithalamus3.62 ± 0.84
Frontal Lobe4.01 ± 0.69
Globus Pallidus4.63 ± 0.79
Hypothalamus3.67 ± 0.62
Insula3.55 ± 0.61
Limbic Lobe4.35 ± 0.75
Mesencephalon4.07 ± 0.6
Myelencephalon4.1 ± 0.72
Occipital Lobe4.24 ± 0.84
Parietal Lobe4.01 ± 0.7
Pontine Tegmentum3.99 ± 0.62
Striatum3.94 ± 0.79
Subthalamus3.49 ± 1.01
Temporal Lobe4 ± 0.62
Thalamus4.01 ± 0.54
White Matter3.46 ± 1
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Hs3st1CBCerebellum54.83
44.34
Hs3st1CTXCerebral cortex33.97
19.91
Hs3st1HIPHippocampal region26.28
15.01
Hs3st1HPFHippocampal formation31.8
22.08
Hs3st1HYHypothalamus9.03
5.46
Hs3st1LSXLateral septal complex7.38
4.41
Hs3st1MBMidbrain19.09
13.49
Hs3st1MYMedulla23.02
16.41
Hs3st1OLFOlfactory bulb67.72
41.1
Hs3st1PPons22.06
16.46
Hs3st1PALPallidum13.16
9.44
Hs3st1RHPRetrohippocampal region40.43
30.18
Hs3st1sAMYStriatum-like amygdalar nuclei9.45
5.79
Hs3st1STRStriatum6.33
3.96
Hs3st1STRdStriatum dorsal region5.09
3.31
Hs3st1STRvStriatum ventral region8.52
4.81
Hs3st1THThalamus36.08
27.59
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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