AutismKB 2.0

Annotation Detail for USP15


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:USP15 ( KIAA0529,MGC131982,MGC149838,MGC74854,UNPH4 )
Gene Full Name: ubiquitin specific peptidase 15
Band: 12q14.1
Quick LinksEntrez ID:9958; OMIM: 604731; Uniprot ID:UBP15_HUMAN; ENSEMBL ID: ENSG00000135655; HGNC ID: 12613
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body8 / 70761113
blastocyst8 / 62319128
fetus47 / 56401283
neonate2 / 3109764
infant0 / 236200 
juvenile0 / 555560 
adult103 / 193912153
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor3 / 3436687
chondrosarcoma7 / 8282384
colorectal tumor4 / 11424635
esophageal tumor2 / 17290115
gastrointestinal tumor5 / 11936941
germ cell tumor17 / 26384564
glioma1 / 1068839
head and neck tumor6 / 13630244
kidney tumor1 / 6895914
leukemia9 / 9584293
liver tumor4 / 9635941
lung tumor4 / 10312738
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal216 / 336030764
ovarian tumor3 / 7668239
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer5 / 10268048
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites1 / 4001524
bladder1 / 2975733
blood18 / 123478145
bone6 / 7165583
bone marrow4 / 4880181
brain24 / 110098921
cervix3 / 4817162
connective tissue8 / 14925553
ear2 / 16212123
embryonic tissue23 / 215722106
esophagus2 / 2020998
eye6 / 21105428
heart2 / 8962622
intestine9 / 23447238
kidney13 / 21177761
larynx1 / 2414541
liver14 / 20774367
lung17 / 33697450
lymph0 / 442700 
lymph node12 / 91610130
mammary gland13 / 15327184
mouth3 / 6705244
muscle8 / 10771574
nerve0 / 157680 
ovary3 / 10205129
pancreas10 / 21481246
parathyroid1 / 2053948
pharynx3 / 4132872
pituitary gland1 / 1658560
placenta18 / 28082564
prostate5 / 18934526
salivary gland1 / 2015549
skin3 / 21057414
spleen1 / 5395218
stomach5 / 9661951
testis37 / 330442111
thymus6 / 8113173
thyroid2 / 4747342
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus16 / 23287868
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210681_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts92.05
Adipocyte24.6
AdrenalCortex10.95
Adrenalgland8.15
Amygdala10.15
Appendix19.3
AtrioventricularNode13.65
BDCA4+_DentriticCells281.95
Bonemarrow18.5
BronchialEpithelialCells31.3
CD105+_Endothelial460.55
CD14+_Monocytes304.6
CD19+_BCells(neg._sel.)162.55
CD33+_Myeloid649.1
CD34+293.35
CD4+_Tcells222
CD56+_NKCells143
CD71+_EarlyErythroid777.95
CD8+_Tcells201
CardiacMyocytes24.75
Caudatenucleus8.65
Cerebellum8.15
CerebellumPeduncles10.7
CiliaryGanglion7
CingulateCortex10.1
Colorectaladenocarcinoma9.95
DorsalRootGanglion10.85
FetalThyroid10.1
Fetalbrain14.85
Fetalliver114.9
Fetallung36.75
GlobusPallidus7.7
Heart13.7
Hypothalamus10.7
Kidney9.05
Leukemia_chronicMyelogenousK-562110.85
Leukemia_promyelocytic-HL-6012.75
Leukemialymphoblastic(MOLT-4)9.25
Liver12.45
Lung10.35
Lymphnode71.85
Lymphoma_burkitts(Daudi)14
Lymphoma_burkitts(Raji)14.25
MedullaOblongata9.55
OccipitalLobe9.1
OlfactoryBulb7.95
Ovary15.25
Pancreas11
PancreaticIslet11.65
ParietalLobe10.6
Pituitary13.1
Placenta10.05
Pons9.6
PrefrontalCortex11.4
Prostate11.7
Salivarygland13.4
SkeletalMuscle18.9
Skin12.3
SmoothMuscle46.85
Spinalcord10.85
SubthalamicNucleus8.4
SuperiorCervicalGanglion21.7
TemporalLobe8.45
Testis7.1
TestisGermCell51.25
TestisIntersitial31.5
TestisLeydigCell18.1
TestisSeminiferousTubule22.7
Thalamus9.65
Thymus7.85
Thyroid15.9
Tongue19.45
Tonsil38.1
Trachea14.2
TrigeminalGanglion16.55
Uterus22.2
UterusCorpus15.45
WholeBlood466.25
Wholebrain6.85
colon10.45
pineal_day15.78
pineal_night20.92
retina12.225
small_intestine9.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P57057
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.22 ± 0.28
Basal Forebrain9.25 ± 0.12
Basal Part of Pons9.44 ± 0.1
Cerebellar Cortex9.63 ± 0.14
Cerebellar Nuclei9.25 ± 0.32
Claustrum9.1 ± 0.32
Epithalamus9.5 ± 0.16
Frontal Lobe9.36 ± 0.31
Globus Pallidus8.89 ± 0.18
Hypothalamus9.44 ± 0.31
Insula9.37 ± 0.23
Limbic Lobe9.34 ± 0.36
Mesencephalon9.26 ± 0.27
Myelencephalon9.26 ± 0.32
Occipital Lobe9.3 ± 0.26
Parietal Lobe9.33 ± 0.25
Pontine Tegmentum9.33 ± 0.3
Striatum9 ± 0.21
Subthalamus9.44 ± 0.37
Temporal Lobe9.41 ± 0.26
Thalamus9.2 ± 0.19
White Matter9.6 ± 0.08
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Usp15CBCerebellum31.85
44.39
Usp15CTXCerebral cortex75.56
58.44
Usp15HIPHippocampal region44.01
53.14
Usp15HPFHippocampal formation56.64
57.31
Usp15HYHypothalamus18.99
16.27
Usp15LSXLateral septal complex14.64
11.37
Usp15MBMidbrain19.44
17.66
Usp15MYMedulla27.52
32.59
Usp15OLFOlfactory bulb65.04
53.19
Usp15PPons27.02
30.22
Usp15PALPallidum10.89
9.82
Usp15RHPRetrohippocampal region84.04
67.91
Usp15sAMYStriatum-like amygdalar nuclei15.01
11.59
Usp15STRStriatum20.65
15.15
Usp15STRdStriatum dorsal region20.68
14.97
Usp15STRvStriatum ventral region26.3
19.44
Usp15THThalamus49.52
41.97
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00001671 29 817 845 DKLDTLVDFPINDLDMSEFLINPNAGPCR Peptide Atlas
UBP15_HUMAN_2 12 2 13 AEGGAADLDTQR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved