AutismKB 2.0

Annotation Detail for CDC27


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Basic Information Top
Gene Symbol:CDC27 ( ANAPC3,APC3,CDC27Hs,D0S1430E,D17S978E,HNUC )
Gene Full Name: cell division cycle 27 homolog (S. cerevisiae)
Band: 17q21.32
Quick LinksEntrez ID:996; OMIM: 116946; Uniprot ID:CDC27_HUMAN; ENSEMBL ID: ENSG00000004897; HGNC ID: 1728
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst3 / 6231948
fetus66 / 564012117
neonate2 / 3109764
infant2 / 2362084
juvenile7 / 55556125
adult111 / 193912157
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma2 / 17475114
breast (mammary gland) tumor12 / 94178127
cervical tumor2 / 3436658
chondrosarcoma9 / 82823108
colorectal tumor9 / 11424678
esophageal tumor0 / 172900 
gastrointestinal tumor8 / 11936967
germ cell tumor18 / 26384568
glioma4 / 10688337
head and neck tumor4 / 13630229
kidney tumor3 / 6895943
leukemia4 / 9584241
liver tumor7 / 9635972
lung tumor1 / 1031279
lymphoma1 / 7175513
non-neoplasia2 / 9725020
normal204 / 336030760
ovarian tumor1 / 7668213
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS8 / 12568063
prostate cancer1 / 1026809
retinoblastoma3 / 4635664
skin tumor14 / 124949112
soft tissue/muscle tissue tumor27 / 125191215
uterine tumor12 / 90257132
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland1 / 3319730
ascites3 / 4001574
bladder2 / 2975767
blood3 / 12347824
bone5 / 7165569
bone marrow4 / 4880181
brain54 / 110098949
cervix2 / 4817141
connective tissue24 / 149255160
ear0 / 162120 
embryonic tissue11 / 21572250
esophagus0 / 202090 
eye9 / 21105442
heart0 / 896260 
intestine17 / 23447272
kidney9 / 21177742
larynx1 / 2414541
liver14 / 20774367
lung14 / 33697441
lymph0 / 442700 
lymph node16 / 91610174
mammary gland17 / 153271110
mouth2 / 6705229
muscle5 / 10771546
nerve1 / 1576863
ovary2 / 10205119
pancreas10 / 21481246
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta13 / 28082546
prostate2 / 18934510
salivary gland0 / 201550 
skin25 / 210574118
spleen2 / 5395237
stomach2 / 9661920
testis17 / 33044251
thymus3 / 8113136
thyroid1 / 4747321
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus24 / 232878103
vascular6 / 51780115
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 217879_at
Cell line Expression level Expression bar
721_B_lymphoblasts36.2
Adipocyte6.6
AdrenalCortex6.7
Adrenalgland5.45
Amygdala8.65
Appendix6.7
AtrioventricularNode4.9
BDCA4+_DentriticCells10.3
Bonemarrow6.5
BronchialEpithelialCells22.5
CD105+_Endothelial65.9
CD14+_Monocytes7.15
CD19+_BCells(neg._sel.)7.15
CD33+_Myeloid8.6
CD34+8.55
CD4+_Tcells7.3
CD56+_NKCells10.85
CD71+_EarlyErythroid554.75
CD8+_Tcells8.3
CardiacMyocytes12.15
Caudatenucleus5.9
Cerebellum5.3
CerebellumPeduncles7.45
CiliaryGanglion4.55
CingulateCortex6.2
Colorectaladenocarcinoma7.25
DorsalRootGanglion5
FetalThyroid6.45
Fetalbrain6.65
Fetalliver44.3
Fetallung5.65
GlobusPallidus4.75
Heart8.25
Hypothalamus7.9
Kidney5.25
Leukemia_chronicMyelogenousK-5625.7
Leukemia_promyelocytic-HL-609.85
Leukemialymphoblastic(MOLT-4)11.3
Liver8.6
Lung6.7
Lymphnode5.75
Lymphoma_burkitts(Daudi)14.5
Lymphoma_burkitts(Raji)9.25
MedullaOblongata6.1
OccipitalLobe6.1
OlfactoryBulb4.95
Ovary4.55
Pancreas5.15
PancreaticIslet7.05
ParietalLobe6.85
Pituitary10.15
Placenta5.25
Pons6.3
PrefrontalCortex8.5
Prostate7.8
Salivarygland5.25
SkeletalMuscle7.35
Skin5.05
SmoothMuscle18.8
Spinalcord7.05
SubthalamicNucleus4.75
SuperiorCervicalGanglion8.3
TemporalLobe6.05
Testis5.65
TestisGermCell6.2
TestisIntersitial6.15
TestisLeydigCell6.65
TestisSeminiferousTubule8.25
Thalamus6.6
Thymus5.25
Thyroid12.55
Tongue6.4
Tonsil6.2
Trachea5.5
TrigeminalGanglion6.45
Uterus7.5
UterusCorpus5.9
WholeBlood7.3
Wholebrain5.65
colon6.85
pineal_day9.18
pineal_night8.74
retina8.05
small_intestine6.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P66777
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.69 ± 0.48
Basal Forebrain7.67 ± 0.18
Basal Part of Pons7.96 ± 0.22
Cerebellar Cortex7.72 ± 0.2
Cerebellar Nuclei7.88 ± 0.23
Claustrum8.04 ± 0.32
Epithalamus7.69 ± 0.32
Frontal Lobe8.06 ± 0.25
Globus Pallidus7.47 ± 0.38
Hypothalamus8.18 ± 0.18
Insula8.09 ± 0.28
Limbic Lobe7.79 ± 0.44
Mesencephalon7.87 ± 0.42
Myelencephalon7.8 ± 0.42
Occipital Lobe7.45 ± 0.51
Parietal Lobe7.89 ± 0.34
Pontine Tegmentum7.92 ± 0.39
Striatum7.37 ± 0.36
Subthalamus8.23 ± 0.06
Temporal Lobe7.97 ± 0.26
Thalamus7.86 ± 0.28
White Matter7.51 ± 0.28
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cdc27CBCerebellum14.57
25.91
Cdc27CTXCerebral cortex50
50
Cdc27HIPHippocampal region50
50
Cdc27HPFHippocampal formation50
50
Cdc27HYHypothalamus50
50
Cdc27LSXLateral septal complex50
50
Cdc27MBMidbrain39.22
41.78
Cdc27MYMedulla36.82
50
Cdc27OLFOlfactory bulb50
50
Cdc27PPons45.34
50
Cdc27PALPallidum48.76
50
Cdc27RHPRetrohippocampal region50
50
Cdc27sAMYStriatum-like amygdalar nuclei50
50
Cdc27STRStriatum50
50
Cdc27STRdStriatum dorsal region50
50
Cdc27STRvStriatum ventral region50
50
Cdc27THThalamus47.65
50
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
CDC27_HUMAN_197 18 197 214 QPETVLTETPQDTIELNR PRIDE
CDC27_HUMAN_432 10 432 441 LDSSIISEGK PRIDE
PAp00024815 25 483 507 EAINILSHLPSHHYNTGWVLCQIGR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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