AutismKB 2.0

Annotation Detail for MVP


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Basic Information Top
Gene Symbol:MVP ( LRP,VAULT1 )
Gene Full Name: major vault protein
Band: 16p11.2
Quick LinksEntrez ID:9961; OMIM: 605088; Uniprot ID:MVP_HUMAN; ENSEMBL ID: ENSG00000013364; HGNC ID: 7531
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst3 / 6231948
fetus9 / 56401215
neonate35 / 310971125
infant1 / 2362042
juvenile6 / 55556107
adult253 / 1939121130
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor13 / 94178138
cervical tumor3 / 3436687
chondrosarcoma8 / 8282396
colorectal tumor25 / 114246218
esophageal tumor2 / 17290115
gastrointestinal tumor30 / 119369251
germ cell tumor18 / 26384568
glioma24 / 106883224
head and neck tumor97 / 136302711
kidney tumor17 / 68959246
leukemia15 / 95842156
liver tumor13 / 96359134
lung tumor17 / 103127164
lymphoma4 / 7175555
non-neoplasia37 / 97250380
normal584 / 3360307173
ovarian tumor5 / 7668265
pancreatic tumor28 / 104616267
primitive neuroectodermal tumor of the CNS7 / 12568055
prostate cancer8 / 10268077
retinoblastoma0 / 463560 
skin tumor21 / 124949168
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor15 / 90257166
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland22 / 33197662
ascites5 / 40015124
bladder9 / 29757302
blood24 / 123478194
bone10 / 71655139
bone marrow4 / 4880181
brain117 / 1100989106
cervix3 / 4817162
connective tissue56 / 149255375
ear0 / 162120 
embryonic tissue11 / 21572250
esophagus3 / 20209148
eye28 / 211054132
heart9 / 89626100
intestine73 / 234472311
kidney85 / 211777401
larynx1 / 2414541
liver16 / 20774377
lung43 / 336974127
lymph2 / 4427045
lymph node6 / 9161065
mammary gland17 / 153271110
mouth82 / 670521222
muscle3 / 10771527
nerve2 / 15768126
ovary9 / 10205188
pancreas30 / 214812139
parathyroid0 / 205390 
pharynx3 / 4132872
pituitary gland0 / 165850 
placenta48 / 280825170
prostate17 / 18934589
salivary gland13 / 20155645
skin84 / 210574398
spleen50 / 53952926
stomach29 / 96619300
testis34 / 330442102
thymus56 / 81131690
thyroid4 / 4747384
tonsil0 / 169990 
trachea25 / 52413476
umbilical cord0 / 136800 
uterus40 / 232878171
vascular33 / 51780637
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202180_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts80
Adipocyte73.15
AdrenalCortex84.05
Adrenalgland151.3
Amygdala16.4
Appendix32.3
AtrioventricularNode19.2
BDCA4+_DentriticCells294.4
Bonemarrow33.1
BronchialEpithelialCells100.95
CD105+_Endothelial27.95
CD14+_Monocytes263.55
CD19+_BCells(neg._sel.)80.4
CD33+_Myeloid238.6
CD34+41.6
CD4+_Tcells266.45
CD56+_NKCells180.9
CD71+_EarlyErythroid7.15
CD8+_Tcells180.8
CardiacMyocytes99.15
Caudatenucleus30.3
Cerebellum26.5
CerebellumPeduncles37.05
CiliaryGanglion22.85
CingulateCortex33.2
Colorectaladenocarcinoma23.8
DorsalRootGanglion25.85
FetalThyroid47.55
Fetalbrain32.2
Fetalliver20.15
Fetallung67.55
GlobusPallidus24.9
Heart63.55
Hypothalamus36.25
Kidney84.9
Leukemia_chronicMyelogenousK-56218.55
Leukemia_promyelocytic-HL-6018.1
Leukemialymphoblastic(MOLT-4)25.9
Liver45.9
Lung423.5
Lymphnode58.75
Lymphoma_burkitts(Daudi)41.65
Lymphoma_burkitts(Raji)61.45
MedullaOblongata27.35
OccipitalLobe22.9
OlfactoryBulb27.6
Ovary22.15
Pancreas57.15
PancreaticIslet118.5
ParietalLobe18.35
Pituitary53.75
Placenta55.15
Pons31
PrefrontalCortex39.95
Prostate60.9
Salivarygland26.05
SkeletalMuscle37.85
Skin25.8
SmoothMuscle271.7
Spinalcord36.25
SubthalamicNucleus31.75
SuperiorCervicalGanglion37.9
TemporalLobe17.7
Testis58.6
TestisGermCell33.65
TestisIntersitial27.4
TestisLeydigCell28.45
TestisSeminiferousTubule28.55
Thalamus32.8
Thymus52.7
Thyroid60
Tongue37.45
Tonsil45.25
Trachea48.4
TrigeminalGanglion33.3
Uterus86.45
UterusCorpus31.5
WholeBlood308.6
Wholebrain20
colon215
pineal_day72.88
pineal_night66.58
retina43.35
small_intestine119.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15530_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.46 ± 0.44
Basal Forebrain5.9 ± 0.28
Basal Part of Pons6.15 ± 0.61
Cerebellar Cortex5.78 ± 0.38
Cerebellar Nuclei6.42 ± 0.34
Claustrum5.24 ± 0.55
Epithalamus6.63 ± 0.47
Frontal Lobe5.97 ± 0.55
Globus Pallidus7.26 ± 0.37
Hypothalamus6.13 ± 0.56
Insula5.58 ± 0.55
Limbic Lobe5.48 ± 0.56
Mesencephalon5.92 ± 0.6
Myelencephalon6.06 ± 0.46
Occipital Lobe6 ± 0.52
Parietal Lobe5.77 ± 0.51
Pontine Tegmentum5.92 ± 0.55
Striatum6.45 ± 0.45
Subthalamus6.27 ± 0.39
Temporal Lobe5.8 ± 0.44
Thalamus6.32 ± 0.39
White Matter7.76 ± 0.33
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
MvpCBCerebellum36.55
55.14
MvpCTXCerebral cortex87.03
72.98
MvpHIPHippocampal region75.72
92.53
MvpHPFHippocampal formation86.87
92.54
MvpHYHypothalamus33.31
26.31
MvpLSXLateral septal complex63.17
45.8
MvpMBMidbrain49.76
47.32
MvpMYMedulla60.46
65.15
MvpOLFOlfactory bulb72.99
70.63
MvpPPons42.89
43.36
MvpPALPallidum40.11
34.77
MvpRHPRetrohippocampal region97.89
91.55
MvpsAMYStriatum-like amygdalar nuclei33.03
26.31
MvpSTRStriatum53.88
42.14
MvpSTRdStriatum dorsal region55.51
43.14
MvpSTRvStriatum ventral region56.94
46.05
MvpTHThalamus53.04
45.83
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
MVP_HUMAN_0 0 0 0 AQALAIETEAELQR PRIDE
MVP_HUMAN_0 0 0 0 AQLELEVSK PRIDE
MVP_HUMAN_0 0 0 0 AQQLAEVEVK PRIDE
MVP_HUMAN_0 0 0 0 DAQGLVLFDVTGQVR PRIDE
MVP_HUMAN_0 0 0 0 DITPLQVVLPNTALHLK PRIDE
MVP_HUMAN_0 0 0 0 DLAVAGPEMQVK PRIDE
MVP_HUMAN_0 0 0 0 ELPPGVEELLNK PRIDE
MVP_HUMAN_0 0 0 0 GAVASVTFDDFHK PRIDE
MVP_HUMAN_0 0 0 0 GPLEYVPSAK PRIDE
MVP_HUMAN_0 0 0 0 HADLEIR PRIDE
MVP_HUMAN_0 0 0 0 HYCTVANPVSR PRIDE
MVP_HUMAN_0 0 0 0 IEGEGSVLQAK PRIDE
MVP_HUMAN_0 0 0 0 ILDQSEAEK PRIDE
MVP_HUMAN_0 0 0 0 IPPYHYIHVLDQNSNVSR PRIDE
MVP_HUMAN_0 0 0 0 KEVEVVEIIQATIIR PRIDE
MVP_HUMAN_0 0 0 0 LAQDPFPLYPGEVLEK PRIDE
MVP_HUMAN_0 0 0 0 LFSVPDFVGDACK PRIDE
MVP_HUMAN_0 0 0 0 LLQSLGLK PRIDE
MVP_HUMAN_0 0 0 0 SLQPLAPR PRIDE
MVP_HUMAN_0 0 0 0 TAVFGFETSEAK PRIDE
MVP_HUMAN_0 0 0 0 VPHNAAVQVYDYR PRIDE
MVP_HUMAN_0 0 0 0 VVFGPELVSLGPEEQFTVLSLSAGRPK PRIDE
MVP_HUMAN_1 8 1 8 ATEEFIIR PRIDE
MVP_HUMAN_107 17 107 123 DITPLQVVLPNTALHLK PRIDE
MVP_HUMAN_124 30 124 153 ALLDFEDKDGDKVVAGDEWLFEGPGTYIPR PRIDE
MVP_HUMAN_154 15 154 168 KEVEVVEIIQATIIR PRIDE
MVP_HUMAN_306 29 306 334 SFFLQPGEQLEQGIQDVYVLSEQQGLLLR PRIDE
MVP_HUMAN_335 25 335 359 ALQPLEEGEDEEKVSHQAGDHWLIR PRIDE
MVP_HUMAN_360 10 360 369 GPLEYVPSAK PRIDE
MVP_HUMAN_360 17 360 376 GPLEYVPSAKVEVVEER PRIDE
MVP_HUMAN_377 17 377 393 QAIPLDENEGIYVQDVK PRIDE
MVP_HUMAN_461 13 461 473 VPHNAAVQVYDYR PRIDE
MVP_HUMAN_479 27 479 505 VVFGPELVSLGPEEQFTVLSLSAGRPK PRIDE
MVP_HUMAN_511 25 511 535 RALCLLLGPDFFTDVITIETADHAR PRIDE
MVP_HUMAN_512 24 512 535 ALCLLLGPDFFTDVITIETADHAR PRIDE
MVP_HUMAN_560 13 560 572 LFSVPDFVGDACK PRIDE
MVP_HUMAN_580 13 580 592 GAVASVTFDDFHK PRIDE
MVP_HUMAN_600 12 600 611 TAVFGFETSEAK PRIDE
MVP_HUMAN_600 23 600 622 TAVFGFETSEAKGPDGMALPRPR PRIDE
MVP_HUMAN_665 14 665 678 TNSQEAAAKHEAQR PRIDE
MVP_HUMAN_67 15 67 81 DAQGLVLFDVTGQVR PRIDE
MVP_HUMAN_704 19 704 722 ELLELEALSMAVESTGTAK PRIDE
MVP_HUMAN_745 16 745 760 LKAQALAIETEAELQR PRIDE
MVP_HUMAN_774 9 774 782 AQLELEVSK PRIDE
MVP_HUMAN_783 10 783 792 AQQLAEVEVK PRIDE
MVP_HUMAN_796 12 796 807 QMTEAIGPSTIR PRIDE
MVP_HUMAN_808 12 808 819 DLAVAGPEMQVK PRIDE
MVP_HUMAN_820 8 820 827 LLQSLGLK PRIDE
MVP_HUMAN_849 11 849 859 GMGPEGQPLGR PRIDE
MVP_HUMAN_861 32 861 892 VASGPSPGEGISPQSAQAPQAPGDNHVVPVLR PRIDE
MVP_HUMAN_9 18 9 26 IPPYHYIHVLDQNSNVSR PRIDE
MVP_HUMAN_91 16 91 106 LAQDPFPLYPGEVLEK PRIDE
MVP_HUMAN_91 33 91 123 LAQDPFPLYPGEVLEKDITPLQVVLPNTALHLK PRIDE
PAp00003633 11 57 67 HYCTVANPVSR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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