AutismKB 2.0

Annotation Detail for CDH1


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Basic Information Top
Gene Symbol:CDH1 ( Arc-1,CD324,CDHE,ECAD,LCAM,UVO )
Gene Full Name: cadherin 1, type 1, E-cadherin (epithelial)
Band: 16q22.1
Quick LinksEntrez ID:999; OMIM: 192090; Uniprot ID:CADH1_HUMAN; ENSEMBL ID: ENSG00000039068; HGNC ID: 1748
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body10 / 70761141
blastocyst15 / 62319240
fetus38 / 56401267
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult364 / 1939121187
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma8 / 17475457
breast (mammary gland) tumor67 / 94178711
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor48 / 114246420
esophageal tumor7 / 17290404
gastrointestinal tumor27 / 119369226
germ cell tumor20 / 26384575
glioma2 / 10688318
head and neck tumor50 / 136302366
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor10 / 96359103
lung tumor8 / 10312777
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal254 / 336030775
ovarian tumor3 / 7668239
pancreatic tumor8 / 10461676
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer16 / 102680155
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor25 / 90257276
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder9 / 29757302
blood4 / 12347832
bone0 / 716550 
bone marrow0 / 488010 
brain12 / 110098910
cervix0 / 481710 
connective tissue2 / 14925513
ear4 / 16212246
embryonic tissue40 / 215722185
esophagus7 / 20209346
eye6 / 21105428
heart3 / 8962633
intestine70 / 234472298
kidney12 / 21177756
larynx10 / 24145414
liver14 / 20774367
lung32 / 33697494
lymph0 / 442700 
lymph node1 / 9161010
mammary gland96 / 153271626
mouth21 / 67052313
muscle3 / 10771527
nerve0 / 157680 
ovary4 / 10205139
pancreas18 / 21481283
parathyroid8 / 20539389
pharynx5 / 41328120
pituitary gland1 / 1658560
placenta49 / 280825174
prostate27 / 189345142
salivary gland0 / 201550 
skin22 / 210574104
spleen2 / 5395237
stomach44 / 96619455
testis5 / 33044215
thymus2 / 8113124
thyroid21 / 47473442
tonsil0 / 169990 
trachea19 / 52413362
umbilical cord0 / 136800 
uterus34 / 232878145
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201131_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.7
Adipocyte4.7
AdrenalCortex5.35
Adrenalgland4.15
Amygdala4.85
Appendix5.3
AtrioventricularNode4
BDCA4+_DentriticCells55
Bonemarrow5.55
BronchialEpithelialCells890.1
CD105+_Endothelial327.45
CD14+_Monocytes5.1
CD19+_BCells(neg._sel.)4.95
CD33+_Myeloid5.95
CD34+142.25
CD4+_Tcells5.05
CD56+_NKCells5.5
CD71+_EarlyErythroid401.2
CD8+_Tcells4.5
CardiacMyocytes6.5
Caudatenucleus4.3
Cerebellum3.85
CerebellumPeduncles5.6
CiliaryGanglion8.85
CingulateCortex4.95
Colorectaladenocarcinoma40.05
DorsalRootGanglion19.6
FetalThyroid444.15
Fetalbrain4.65
Fetalliver277
Fetallung321.75
GlobusPallidus3.6
Heart6.6
Hypothalamus5.1
Kidney71.25
Leukemia_chronicMyelogenousK-5624.25
Leukemia_promyelocytic-HL-604.25
Leukemialymphoblastic(MOLT-4)3.8
Liver82.5
Lung168.25
Lymphnode11.6
Lymphoma_burkitts(Daudi)6.25
Lymphoma_burkitts(Raji)6.95
MedullaOblongata4.3
OccipitalLobe4.25
OlfactoryBulb65.35
Ovary3.25
Pancreas459.9
PancreaticIslet426.45
ParietalLobe5.15
Pituitary126.45
Placenta618.45
Pons4.65
PrefrontalCortex5.85
Prostate1164.25
Salivarygland227.25
SkeletalMuscle5.9
Skin69.35
SmoothMuscle5.35
Spinalcord5.15
SubthalamicNucleus4.45
SuperiorCervicalGanglion6.45
TemporalLobe4.4
Testis4.1
TestisGermCell3.9
TestisIntersitial4
TestisLeydigCell4.9
TestisSeminiferousTubule4.1
Thalamus4.95
Thymus49.25
Thyroid2192.4
Tongue176.35
Tonsil23.7
Trachea325.7
TrigeminalGanglion13.4
Uterus7.25
UterusCorpus4.4
WholeBlood5.15
Wholebrain3.9
colon958.5
pineal_day5.9
pineal_night5.76
retina86.425
small_intestine1194.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P125968
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.1 ± 0.99
Basal Forebrain1.63 ± 0.2
Basal Part of Pons1.29 ± 0.36
Cerebellar Cortex1.46 ± 0.67
Cerebellar Nuclei1.95 ± 0.74
Claustrum2.56 ± 0.82
Epithalamus1.35 ± 0.73
Frontal Lobe1.46 ± 0.55
Globus Pallidus2.27 ± 0.32
Hypothalamus1.72 ± 0.64
Insula1.55 ± 0.49
Limbic Lobe1.66 ± 0.62
Mesencephalon1.78 ± 0.65
Myelencephalon1.67 ± 0.63
Occipital Lobe1.71 ± 0.56
Parietal Lobe1.73 ± 0.87
Pontine Tegmentum1.68 ± 0.61
Striatum1.8 ± 0.48
Subthalamus1.84 ± 0.61
Temporal Lobe1.51 ± 0.5
Thalamus1.63 ± 0.58
White Matter2.26 ± 0.49
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cdh1LSXLateral septal complex0
0
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
CADH1_HUMAN_154 19 154 172 DWVIPPISCPENEKGPFPK PRIDE
CADH1_HUMAN_381 16 381 396 GQVPENEANVVITTLK PRIDE
CADH1_HUMAN_524 21 524 544 IWRDTANWLEINPDTGAISTR PRIDE
CADH1_HUMAN_796 20 796 815 YLPRPANPDEIGNFIDENLK PRIDE
PAp00011698 7 599 605 TIFFCER Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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