Annotation Detail for CASP8AP2
Basic Information Top
| Gene Symbol: | CASP8AP2 ( CED-4,FLASH,FLJ11208,KIAA1315,RIP25 ) |
|---|---|
| Gene Full Name: | caspase 8 associated protein 2 |
| Band: | 6q15 |
| Quick Links | Entrez ID:9994; OMIM: 606880; Uniprot ID:C8AP2_HUMAN; ENSEMBL ID: ENSG00000118412; HGNC ID: 1510 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.558218
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 2 / 70761 | 28 |  |
| blastocyst | 4 / 62319 | 64 |  |
| fetus | 22 / 564012 | 39 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 1 / 55556 | 17 | |
| adult | 38 / 1939121 | 19 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 1 / 94178 | 10 |  |
| cervical tumor | 1 / 34366 | 29 | |
| chondrosarcoma | 2 / 82823 | 24 | |
| colorectal tumor | 1 / 114246 | 8 | |
| esophageal tumor | 1 / 17290 | 57 | |
| gastrointestinal tumor | 2 / 119369 | 16 | |
| germ cell tumor | 4 / 263845 | 15 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 3 / 136302 | 22 | |
| kidney tumor | 1 / 68959 | 14 | |
| leukemia | 4 / 95842 | 41 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 4 / 97250 | 41 | |
| normal | 79 / 3360307 | 23 | |
| ovarian tumor | 2 / 76682 | 26 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 1 / 46356 | 21 | |
| skin tumor | 1 / 124949 | 8 | |
| soft tissue/muscle tissue tumor | 3 / 125191 | 23 | |
| uterine tumor | 3 / 90257 | 33 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 2 / 40015 | 49 | |
| bladder | 0 / 29757 | 0 | |
| blood | 1 / 123478 | 8 | |
| bone | 1 / 71655 | 13 | |
| bone marrow | 2 / 48801 | 40 | |
| brain | 17 / 1100989 | 15 | |
| cervix | 1 / 48171 | 20 | |
| connective tissue | 5 / 149255 | 33 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 10 / 215722 | 46 | |
| esophagus | 1 / 20209 | 49 | |
| eye | 3 / 211054 | 14 | |
| heart | 3 / 89626 | 33 | |
| intestine | 3 / 234472 | 12 | |
| kidney | 5 / 211777 | 23 | |
| larynx | 2 / 24145 | 82 | |
| liver | 2 / 207743 | 9 | |
| lung | 3 / 336974 | 8 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 4 / 91610 | 43 | |
| mammary gland | 3 / 153271 | 19 | |
| mouth | 2 / 67052 | 29 | |
| muscle | 9 / 107715 | 83 | |
| nerve | 1 / 15768 | 63 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 5 / 214812 | 23 | |
| parathyroid | 1 / 20539 | 48 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 6 / 280825 | 21 | |
| prostate | 0 / 189345 | 0 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 1 / 210574 | 4 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 0 / 96619 | 0 | |
| testis | 3 / 330442 | 9 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 1 / 47473 | 21 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 1 / 52413 | 19 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 6 / 232878 | 25 | |
| vascular | 4 / 51780 | 77 | |
Microarray in - Probe name: A_23_P58898
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 5.97 ± 0.32 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 6.16 ± 0.18 | |
| Basal Part of Pons | 6.1 ± 0.36 | |
| Cerebellar Cortex | 6.52 ± 0.19 | |
| Cerebellar Nuclei | 6.12 ± 0.47 | |
| Claustrum | 6.07 ± 0.54 | |
| Epithalamus | 6.2 ± 0.35 | |
| Frontal Lobe | 6.11 ± 0.34 | |
| Globus Pallidus | 5.99 ± 0.33 | |
| Hypothalamus | 6.2 ± 0.39 | |
| Insula | 6.18 ± 0.31 | |
| Limbic Lobe | 6.02 ± 0.43 | |
| Mesencephalon | 6.22 ± 0.36 | |
| Myelencephalon | 6.14 ± 0.39 | |
| Occipital Lobe | 6.48 ± 0.29 | |
| Parietal Lobe | 6.25 ± 0.37 | |
| Pontine Tegmentum | 6.16 ± 0.39 | |
| Striatum | 5.83 ± 0.3 | |
| Subthalamus | 6.51 ± 0.23 | |
| Temporal Lobe | 6.13 ± 0.33 | |
| Thalamus | 6.25 ± 0.35 | |
| White Matter | 6.41 ± 0.26 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Casp8ap2 | CB | Cerebellum | 0.53 | |
| 0.92 | | |||
| Casp8ap2 | CTX | Cerebral cortex | 0.22 | |
| 0.28 | | |||
| Casp8ap2 | HIP | Hippocampal region | 0.14 | |
| 0.13 | | |||
| Casp8ap2 | HPF | Hippocampal formation | 0.11 | |
| 0.11 | | |||
| Casp8ap2 | HY | Hypothalamus | 0.04 | |
| 0.03 | | |||
| Casp8ap2 | LSX | Lateral septal complex | 0 | |
| 0 | | |||
| Casp8ap2 | MB | Midbrain | 0.24 | |
| 0.31 | | |||
| Casp8ap2 | MY | Medulla | 2.06 | |
| 2.39 | | |||
| Casp8ap2 | OLF | Olfactory bulb | 0.42 | |
| 1.65 | | |||
| Casp8ap2 | P | Pons | 0.29 | |
| 0.43 | | |||
| Casp8ap2 | PAL | Pallidum | 0.01 | |
| 0 | | |||
| Casp8ap2 | RHP | Retrohippocampal region | 0.07 | |
| 0.09 | | |||
| Casp8ap2 | sAMY | Striatum-like amygdalar nuclei | 0.05 | |
| 0.07 | | |||
| Casp8ap2 | STR | Striatum | 0.07 | |
| 0.06 | | |||
| Casp8ap2 | STRd | Striatum dorsal region | 0.07 | |
| 0.07 | | |||
| Casp8ap2 | STRv | Striatum ventral region | 0.1 | |
| 0.06 | | |||
| Casp8ap2 | TH | Thalamus | 0.08 | |
| 0.11 | |