AutismKB 2.0

Annotation Detail for SCO2


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Basic Information Top
Gene Symbol:SCO2 ( MGC125823,MGC125825,SCO1L )
Gene Full Name: SCO cytochrome oxidase deficient homolog 2 (yeast)
Band: 22q13.33
Quick LinksEntrez ID:9997; OMIM: 604272; Uniprot ID:SCO2_HUMAN; ENSEMBL ID: ENSG00000130489; HGNC ID: 10604
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205241_at
Cell line Expression level Expression bar
721_B_lymphoblasts25.15
Adipocyte7.7
AdrenalCortex6.9
Adrenalgland5.65
Amygdala5.45
Appendix6
AtrioventricularNode4.35
BDCA4+_DentriticCells244.9
Bonemarrow5.75
BronchialEpithelialCells32.5
CD105+_Endothelial26.95
CD14+_Monocytes476.3
CD19+_BCells(neg._sel.)16.75
CD33+_Myeloid622.2
CD34+21.55
CD4+_Tcells6.45
CD56+_NKCells13.25
CD71+_EarlyErythroid4.95
CD8+_Tcells6.05
CardiacMyocytes7.65
Caudatenucleus5.35
Cerebellum4.9
CerebellumPeduncles8.45
CiliaryGanglion4.25
CingulateCortex6.05
Colorectaladenocarcinoma6.8
DorsalRootGanglion4.4
FetalThyroid7.3
Fetalbrain5.85
Fetalliver5.15
Fetallung5.3
GlobusPallidus4.3
Heart47.45
Hypothalamus6.6
Kidney5
Leukemia_chronicMyelogenousK-5625.4
Leukemia_promyelocytic-HL-6024.7
Leukemialymphoblastic(MOLT-4)6.05
Liver76.15
Lung37.8
Lymphnode8.65
Lymphoma_burkitts(Daudi)21.5
Lymphoma_burkitts(Raji)20.65
MedullaOblongata5.4
OccipitalLobe5.3
OlfactoryBulb4.6
Ovary3.9
Pancreas4.7
PancreaticIslet7.1
ParietalLobe6.1
Pituitary6.95
Placenta6.2
Pons5.75
PrefrontalCortex6.6
Prostate7.6
Salivarygland4.8
SkeletalMuscle7.2
Skin4.45
SmoothMuscle7.9
Spinalcord6.35
SubthalamicNucleus5.35
SuperiorCervicalGanglion6.75
TemporalLobe5.8
Testis8.6
TestisGermCell4.95
TestisIntersitial5
TestisLeydigCell5.9
TestisSeminiferousTubule5.1
Thalamus6.3
Thymus20.85
Thyroid7.6
Tongue5.75
Tonsil10
Trachea5.05
TrigeminalGanglion6.15
Uterus4.85
UterusCorpus5.5
WholeBlood19.85
Wholebrain12.45
colon6.45
pineal_day6.68
pineal_night7.08
retina6.775
small_intestine6.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9138_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.23 ± 0.55
Basal Forebrain9.37 ± 0.52
Basal Part of Pons9.44 ± 0.44
Cerebellar Cortex8.89 ± 0.57
Cerebellar Nuclei9.46 ± 0.43
Claustrum9.68 ± 0.84
Epithalamus8.68 ± 0.7
Frontal Lobe9.26 ± 0.64
Globus Pallidus9.76 ± 0.55
Hypothalamus9.12 ± 0.35
Insula8.93 ± 0.49
Limbic Lobe9.42 ± 0.7
Mesencephalon9.34 ± 0.48
Myelencephalon9.33 ± 0.66
Occipital Lobe9.23 ± 0.79
Parietal Lobe9.14 ± 0.61
Pontine Tegmentum8.99 ± 0.59
Striatum9.36 ± 0.62
Subthalamus8.31 ± 0.9
Temporal Lobe9.13 ± 0.64
Thalamus9.29 ± 0.59
White Matter9.48 ± 0.31
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00361812 18 41 58 QGPAETGGQGQPQGPGLR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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