AutismKB 2.0

Annotation Detail for NAT2


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Basic Information Top
Gene Symbol:NAT2 ( AAC2,PNAT )
Gene Full Name: N-acetyltransferase 2 (arylamine N-acetyltransferase)
Band: 8p22
Quick LinksEntrez ID:10; OMIM: 612182; Uniprot ID:ARY2_HUMAN; ENSEMBL ID: ENSG00000156006; HGNC ID: 7646
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
246Phosphotyrosine (By similarity).
Location(AA) Modifications Resource
246Phosphotyrosine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
125Phosphoserine(CK2)HMM predict
127Phosphoserine(IKK)HMM predict
129Phosphoserine(ATM)HMM predict
212Phosphoserine(CDC2)HMM predict
214O-linkedHMM predict
219O-linkedHMM predict
220O-linkedHMM predict
232Phosphotyrosine(SRC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000015
  • Location:chr8 18293034-18303002
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 18288660 18289003 343 4203
H3ac HepG2E 18285030 18285243 213 7898
NRSF pAbJurkat 18288978 18289545 567 3773
RARA MCF7GSE15244 18282406 18283152 746 10256
RARG MCF7GSE15244 18282472 18283380 908 10109
TFAP2C MCF7GSE21234 18282191 18282944 753 10467
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
TFAP2C MCF7GSE21234 18317755 18318367 612 15059
No data
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018