AutismKB 2.0

Annotation Detail for ADA


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Basic Information Top
Gene Symbol:ADA ( - )
Gene Full Name: adenosine deaminase
Band: 20q13.12
Quick LinksEntrez ID:100; OMIM: 608958; Uniprot ID:ADA_HUMAN; ENSEMBL ID: ENSG00000196839; HGNC ID: 186
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
54N6-acetyllysine.
232N6-acetyllysine.
Location(AA) Modifications Resource
2N-acetylalanine.Swiss-Prot 53.0
Location(AA) Modification Resource
67Phosphotyrosine(Syk)HMM predict
68Phosphotyrosine(INSR)HMM predict
97Phosphotyrosine(Abl)HMM predict
125Phosphothreonine(MAPK)HMM predict
192O-linkedHMM predict
201Phosphotyrosine(EGFR)HMM predict
308Phosphotyrosine(Syk)HMM predict
311Phosphothreonine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000022
  • Location:chr20 42681577-42713789
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
NFkBII GM12878GSE19485 42713735 42715104 1369 630
P300 T30-glioblastomaGSE21026 42732817 42733395 578 19317
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 42704309 42709555 5246 0
H3ac HepG2E 42704440 42705219 779 0
H3ac HepG2E 42710990 42711760 770 0
TAF HelaGSE8489 42704371 42704740 369 0
TFAP2C MCF7GSE21234 42705807 42706506 699 0
hScc1 BcellGSE12603 42684984 42685243 259 0
hScc1 BcellGSE12603 42688437 42688829 392 0
hScc1 BcellGSE12603 42691846 42692028 182 0
hScc1 BcellGSE12603 42693678 42694023 345 0
hScc1 BcellGSE12603 42704371 42705219 848 0
hScc1 BcellGSE12603 42713410 42714045 635 0
p130 QuiescentGSE19898 42704561 42704950 389 0
p130 SenescentGSE19898 42704490 42705050 560 0
p130 shRbSenescentGSE19898 42704553 42705119 566 0
p130 shRbSenescentGSE19898 42708872 42709284 412 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
16407 EST chr20 42593970 42686302 46 mRNA ADA chr20 42681577 42713790Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018