AutismKB 2.0

Annotation Detail for CDH2


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Basic Information Top
Gene Symbol:CDH2 ( CD325,CDHN,CDw325,NCAD )
Gene Full Name: cadherin 2, type 1, N-cadherin (neuronal)
Band: 18q12.1
Quick LinksEntrez ID:1000; OMIM: 114020; Uniprot ID:CADH2_HUMAN; ENSEMBL ID: ENSG00000170558; HGNC ID: 1759
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
190N-linked (GlcNAc...) (Potential).
273N-linked (GlcNAc...).
325N-linked (GlcNAc...) (Potential).
402N-linked (GlcNAc...).
572N-linked (GlcNAc...).
651N-linked (GlcNAc...) (Potential).
692N-linked (GlcNAc...).
785Phosphotyrosine.
Location(AA) Modifications Resource
190N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
273N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
325N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
402N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
572N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
651N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
692N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
785Phosphotyrosine.Swiss-Prot 53.0
852Phosphotyrosine (Src)Phospho.ELM 6.0
884Phosphotyrosine (Src)Phospho.ELM 6.0
Location(AA) Modification Resource
41Phosphotyrosine(Syk)HMM predict
41Phosphotyrosine(SRC)HMM predict
74Phosphoserine(ATM)HMM predict
135Phosphoserine(PKG)HMM predict
196Phosphoserine(IKK)HMM predict
273N-linkedHMM predict
280O-linkedHMM predict
314Phosphoserine(IKK)HMM predict
314O-linkedHMM predict
315O-linkedHMM predict
315Phosphothreonine(MAPK)HMM predict
315Phosphothreonine(CDK)HMM predict
325N-linkedHMM predict
357N-linkedHMM predict
365O-linkedHMM predict
367O-linkedHMM predict
402N-linkedHMM predict
445Phosphothreonine(PKC)HMM predict
480O-linkedHMM predict
481O-linkedHMM predict
483O-linkedHMM predict
527Phosphotyrosine(INSR)HMM predict
572N-linkedHMM predict
586O-linkedHMM predict
620Phosphoserine(IKK)HMM predict
622N-linkedHMM predict
628SulfotyrosineHMM predict
644Phosphoserine(CDC2)HMM predict
651N-linkedHMM predict
676Phosphotyrosine(INSR)HMM predict
785Phosphotyrosine(Jak)HMM predict
785SulfotyrosineHMM predict
785Phosphotyrosine(INSR)HMM predict
788Phosphoserine(ATM)HMM predict
824O-linkedHMM predict
865Phosphoserine(IKK)HMM predict
874N-linkedHMM predict
875Phosphoserine(CK1)HMM predict
876Phosphoserine(CK1)HMM predict
878Phosphoserine(CK1)HMM predict
884Phosphotyrosine(SRC)HMM predict
884Phosphotyrosine(EGFR)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001792
  • Location:chr18 23784933-24011188
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 24011155 24011701 546 240
Oct1 H2O2-HelaGSE14283 24023434 24023464 30 12261
Oct1 HelaGSE14283 24023434 24023488 54 12273
hScc1 BcellGSE12603 24011343 24011701 358 334
hScc1 BcellGSE12603 24023411 24023683 272 12359
hScc1 CdLSGSE12603 24023411 24023820 409 12427
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 24009354 24010743 1389 0
ER E2-MCF7GSE14664 23847989 23848024 35 0
ER Fulvestrant-MCF7GSE14664 23990962 23990996 34 0
GABP HelaGSE8489 23990311 23991174 863 0
H3K27me3 colorectalcancer 24008774 24009393 619 0
H3ac HepG2E 24008044 24009230 1186 0
H3ac HepG2E 24010078 24010489 411 0
Nanog hESGSE18292 23798835 23799247 412 0
Nanog hESGSE18292 23920705 23921105 400 0
Nanog hESGSE18292 23989193 23989625 432 0
Oct1 H2O2-HelaGSE14283 23931344 23931385 41 0
Oct1 HelaGSE14283 23847989 23848022 33 0
Oct1 HelaGSE14283 23931345 23931384 39 0
Oct1 HelaGSE14283 23960089 23960136 47 0
Oct1 HelaGSE14283 23972006 23972042 36 0
Oct1 HelaGSE14283 23990962 23990997 35 0
Oct1 HelaGSE14283 24006942 24006971 29 0
P300 T0-glioblastomaGSE21026 23981440 23982240 800 0
P300 T30-glioblastomaGSE21026 23830628 23831241 613 0
P300 T30-glioblastomaGSE21026 23899327 23899812 485 0
hScc1 BcellGSE12603 23962662 23962810 148 0
hScc1 BcellGSE12603 24009393 24010132 739 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018