AutismKB 2.0

Annotation Detail for PDCD6IP


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Basic Information Top
Gene Symbol:PDCD6IP ( AIP1,Alix,DRIP4,HP95,MGC17003 )
Gene Full Name: programmed cell death 6 interacting protein
Band: 3p22.3
Quick LinksEntrez ID:10015; OMIM: 608074; Uniprot ID:PDC6I_HUMAN; ENSEMBL ID: ENSG00000170248; HGNC ID: 8766
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
48N6-acetyllysine.
215N6-acetyllysine.
730Phosphoserine.
738Phosphothreonine.
741Phosphothreonine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
47Phosphoserine(CK1)HMM predict
176Phosphothreonine(PKC)HMM predict
233Phosphotyrosine(Syk)HMM predict
294SulfotyrosineHMM predict
362Phosphoserine(IKK)HMM predict
423Phosphoserine(CAMK2)HMM predict
432Phosphothreonine(PKC)HMM predict
464Phosphothreonine(CK2)HMM predict
479Phosphothreonine(MAPK)HMM predict
479Phosphothreonine(CDC2)HMM predict
519Phosphothreonine(PKA)HMM predict
600Phosphoserine(CK1)HMM predict
600Phosphoserine(CK2)HMM predict
618Phosphoserine(PKC)HMM predict
642Phosphoserine(PKG)HMM predict
700Phosphothreonine(PKC)HMM predict
718PhosphoserineHMM predict
721Phosphoserine(IKK)HMM predict
721O-linkedHMM predict
724O-linkedHMM predict
730O-linkedHMM predict
738Phosphothreonine(CDK)HMM predict
741Phosphothreonine(MAPK)HMM predict
770O-linkedHMM predict
775Phosphoserine(CDK)HMM predict
775Phosphoserine(CDC2)HMM predict
775O-linkedHMM predict
781O-linkedHMM predict
787O-linkedHMM predict
787Phosphoserine(ATM)HMM predict
789Phosphothreonine(MAPK)HMM predict
789O-linkedHMM predict
789O-linkedHMM predict
789O-linkedHMM predict
792O-linkedHMM predict
829SulfotyrosineHMM predict
853O-linkedHMM predict
864Phosphotyrosine(Syk)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_013374
  • Location:chr3 33814560-33886197
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 33804006 33804331 325 10392
CTCF CD4SISSRdata 33804006 33804331 325 10392
CTCF G2GSE9613 33803744 33804243 499 10567
ER E2-MCF7GSE14664 33813441 33813490 49 1095
ER Fulvestrant-MCF7GSE14664 33813436 33813482 46 1102
Myc K562GSE19551 33807952 33808649 697 6260
USF1 HepG2E 33812325 33813152 827 1822
hScc1 BcellGSE12603 33803708 33804243 535 10585
hScc1 CdLSGSE12603 33803780 33804243 463 10549
hScc1 G2GSE9613 33803670 33804243 573 10604
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 33899980 33900208 228 13897
CTCF CD4SISSRdata 33899980 33900208 228 13897
Fos K562GSE19551 33905676 33906624 948 19953
hScc1 BcellGSE12603 33898000 33898275 275 11940
hScc1 BcellGSE12603 33900033 33900421 388 14030
hScc1 CdLSGSE12603 33900033 33900490 457 14064
hScc1 G2GSE9613 33900033 33900284 251 13961
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 33815246 33815648 402 0
ER MCF7GSE19013 33814472 33815156 684 0
ETS1 JurkatGSE17954 33814539 33815731 1192 0
FOXA1 MCF7GSE15244 33814621 33815721 1100 0
H3ac HepG2E 33816716 33817515 799 0
NRSF JurkatSISSRdata 33815020 33815313 293 0
PHF8 293TGSE20725 33814643 33815941 1298 0
PHF8 HeLaGSE20725 33814565 33815900 1335 0
PHF8 Hs68minusFBSGSE20725 33814481 33816049 1568 0
PHF8 Hs68plusFBSGSE20725 33814593 33816067 1474 0
TAFII hESGSE17917 33814856 33815768 912 0
USF1 HepG2E 33814151 33816135 1984 0
USF2 HepG2E 33814151 33815246 1095 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-15a hsa-mir-15a 13 18362358
hsa-miR-15a* hsa-mir-15a 13 18362358
hsa-miR-16 hsa-mir-16-1 13 18362358
hsa-miR-16 hsa-mir-16-2 3 18362358
hsa-miR-16-1* hsa-mir-16-1 13 18362358
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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