AutismKB 2.0

Annotation Detail for GNE


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Basic Information Top
Gene Symbol:GNE ( DMRV,GLCNE,IBM2,NM,Uae1 )
Gene Full Name: glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
Band: 9p13.3
Quick LinksEntrez ID:10020; OMIM: 603824; Uniprot ID:GLCNE_HUMAN; ENSEMBL ID: ENSG00000159921; HGNC ID: 23657
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
54SulfotyrosineHMM predict
197Phosphotyrosine(INSR)HMM predict
214Phosphotyrosine(INSR)HMM predict
397Phosphoserine(ATM)HMM predict
502Phosphothreonine(MAPK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_005476
  • Location:chr9 36204440-36248400
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 36247802 36249025 1223 13
P300 T30-glioblastomaGSE21026 36248263 36249286 1023 374
PHF8 HeLaGSE20725 36247834 36249298 1464 166
PHF8 Hs68plusFBSGSE20725 36247773 36249371 1598 172
Rb QuiescentGSE19898 36248289 36248655 366 72
Rb SenescentGSE19898 36248234 36248839 605 136
VDR GM10855-UnstimGSE22484 36247676 36249344 1668 110
hScc1 BcellGSE12603 36248308 36248691 383 99
p130 shRbQuiescentGSE19898 36248540 36249077 537 408
p130 shRbSenescentGSE19898 36248276 36248971 695 223
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 H2O2-HelaGSE14283 36208531 36208558 27 0
Oct1 HelaGSE14283 36220644 36220676 32 0
PHF8 293TGSE20725 36247752 36249040 1288 0
p130 SenescentGSE19898 36247850 36248204 354 0
p130 shRbQuiescentGSE19898 36247840 36248453 613 0
p130 shRbSenescentGSE19898 36247838 36248265 427 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
26400 HTC chr9 36180927 36294778 43961 mRNA GNE chr9 36204440 36248401 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018