AutismKB 2.0

Annotation Detail for TROAP


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Basic Information Top
Gene Symbol:TROAP ( TASTIN )
Gene Full Name: trophinin associated protein (tastin)
Band: 12q13.12
Quick LinksEntrez ID:10024; OMIM: 603872; Uniprot ID:TROAP_HUMAN; ENSEMBL ID: ENSG00000135451; HGNC ID: 12327
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
16Phosphoserine.
18Phosphothreonine.
98Phosphoserine.
170Phosphoserine.
271Phosphoserine.
307Phosphoserine.
324Phosphoserine.
334Phosphoserine.
344Phosphoserine.
358Phosphothreonine.
362Phosphoserine.
363Phosphothreonine.
376Phosphoserine.
Location(AA) Modifications Resource
334Phosphoserine.Swiss-Prot 53.0
344Phosphoserine.Swiss-Prot 53.0
376Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
7Phosphothreonine(PKC)HMM predict
16Phosphoserine(CDC2)HMM predict
18Phosphothreonine(MAPK)HMM predict
20O-linkedHMM predict
30Phosphothreonine(MAPK)HMM predict
34O-linkedHMM predict
36O-linkedHMM predict
86Phosphoserine(ATM)HMM predict
98Phosphoserine(CDC2)HMM predict
98Phosphoserine(MAPK)HMM predict
177Phosphothreonine(CDK)HMM predict
177Phosphothreonine(MAPK)HMM predict
179Phosphothreonine(PKA)HMM predict
179Phosphothreonine(MAPK)HMM predict
213Phosphoserine(MAPK)HMM predict
213Phosphoserine(CDC2)HMM predict
241Phosphoserine(CK1)HMM predict
243Phosphoserine(ATM)HMM predict
262O-linkedHMM predict
324Phosphoserine(CDC2)HMM predict
334Phosphoserine(CDC2)HMM predict
334O-linkedHMM predict
358Phosphothreonine(PKA)HMM predict
358O-linkedHMM predict
417O-linkedHMM predict
421Phosphoserine(IKK)HMM predict
422N-linkedHMM predict
424Phosphothreonine(CDK)HMM predict
480N-linkedHMM predict
485N-linkedHMM predict
630Phosphoserine(ATM)HMM predict
661S-palmitoylHMM predict
662S-palmitoylHMM predict
670O-linkedHMM predict
671O-linkedHMM predict
683Phosphoserine(IKK)HMM predict
739O-linkedHMM predict
744O-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_005480
  • Location:chr12 48003328-48011779
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Fos K562GSE19551 47995721 47996100 379 7418
Fos K562GSE19551 48002755 48003487 732 208
H3K4me2 HCT116GSE10453 48002060 48002507 447 1045
H3K4me3 colorectalcancer 48002284 48002507 223 933
H3ac HepG2E 48002032 48002507 475 1059
PHF8 293TGSE20725 48002322 48003733 1411 301
PHF8 HeLaGSE20725 48002431 48003978 1547 124
Rb SenescentGSE19898 48002940 48003499 559 109
p130 QuiescentGSE19898 48002891 48003751 860 8
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 48011768 48011913 145 61
CTCF CD4SISSRdata 48011768 48011913 145 61
CTCF HelaGSE12889 48011737 48012101 364 140
Myc K562GSE19551 48011546 48012096 550 42
hScc1 BcellGSE12603 48011568 48012124 556 67
hScc1 CdLSGSE12603 48011604 48011974 370 10
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 48003117 48004023 906 0
CTCF G2GSE9613 48005755 48006019 264 0
CTCF G2GSE9613 48006713 48006932 219 0
CTCF G2GSE9613 48010391 48012275 1884 0
E2F4 G0GSE7516 48002876 48004192 1316 0
E2F4 SGSE7516 48003150 48003837 687 0
FOXA1 MCF7GSE15244 48003246 48003953 707 0
H3ac HepG2E 48003319 48003905 586 0
LIN54 G0GSE7516 48002913 48004107 1194 0
LIN9 G0GSE7516 48002876 48004250 1374 0
LIN9 SGSE7516 48002913 48004250 1337 0
NRSF pAbJurkat 48006433 48006897 464 0
RARG MCF7GSE15244 48003382 48003989 607 0
hScc1 BcellGSE12603 48003645 48003953 308 0
hScc1 G2GSE9613 48011332 48012010 678 0
p130 SenescentGSE19898 48002885 48004242 1357 0
p130 shRbQuiescentGSE19898 48002783 48003984 1201 0
p130 shRbSenescentGSE19898 48002796 48003905 1109 0
p130 G0GSE7516 48002876 48004156 1280 0
p130 SGSE7516 48003150 48004107 957 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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