AutismKB 2.0

Annotation Detail for CDH5


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Basic Information Top
Gene Symbol:CDH5 ( 7B4,CD144,FLJ17376 )
Gene Full Name: cadherin 5, type 2 (vascular endothelium)
Band: 16q21
Quick LinksEntrez ID:1003; OMIM: 601120; Uniprot ID:CADH5_HUMAN; ENSEMBL ID: ENSG00000179776; HGNC ID: 1764
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
61N-linked (GlcNAc...) (Potential).
112N-linked (GlcNAc...).
157N-linked (GlcNAc...) (Potential).
362N-linked (GlcNAc...) (Potential).
442N-linked (GlcNAc...).
523N-linked (GlcNAc...).
535N-linked (GlcNAc...).
685Phosphotyrosine.
Location(AA) Modifications Resource
61N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
112N-linked (GlcNAc...).Swiss-Prot 53.0
157N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
362N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
442N-linked (GlcNAc...).Swiss-Prot 53.0
523N-linked (GlcNAc...).Swiss-Prot 53.0
535N-linked (GlcNAc...).Swiss-Prot 53.0
Location(AA) Modification Resource
37Phosphoserine(IKK)HMM predict
61N-linkedHMM predict
63Phosphoserine(CK1)HMM predict
112N-linkedHMM predict
133Phosphothreonine(MAPK)HMM predict
157N-linkedHMM predict
164O-linkedHMM predict
168O-linkedHMM predict
199Phosphotyrosine(INSR)HMM predict
327Phosphotyrosine(INSR)HMM predict
329SulfotyrosineHMM predict
362N-linkedHMM predict
413Phosphoserine(CAMK2)HMM predict
413Phosphoserine(PKG)HMM predict
413Phosphoserine(PKA)HMM predict
428Phosphotyrosine(EGFR)HMM predict
455Phosphothreonine(CDC2)HMM predict
457O-linkedHMM predict
461Phosphoserine(PKG)HMM predict
508Phosphothreonine(MAPK)HMM predict
523N-linkedHMM predict
529N-linkedHMM predict
535N-linkedHMM predict
569O-linkedHMM predict
685Phosphotyrosine(Abl)HMM predict
738Phosphoserine(IKK)HMM predict
744Phosphoserine(CK1)HMM predict
745Phosphoserine(CK1)HMM predict
753Phosphoserine(CK1)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001795
  • Location:chr16 64958063-64996188
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 64948912 64949158 246 9029
CTCF CD4SISSRdata 64948912 64949158 246 9029
CTCF G2GSE9613 64948834 64949140 306 9077
CTCF G2GSE9613 64957495 64958019 524 307
P300 T0-glioblastomaGSE21026 64948886 64949396 510 8923
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 64997820 64998247 427 1845
CTCF CD4SISSRdata 64997820 64998247 427 1845
CTCF G2GSE9613 64997721 64998596 875 1970
TAF HelaGSE8489 64999785 65000179 394 3794
hScc1 BcellGSE12603 64997651 64998596 945 1935
hScc1 CdLSGSE12603 64997335 64998338 1003 1648
hScc1 G2GSE9613 64997687 64998596 909 1953
p130 SenescentGSE19898 64999454 65000403 949 3740
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 64985896 64986766 870 0
CBP T30-glioblastomaGSE21026 64973460 64975003 1543 0
CTCF G2GSE9613 64992101 64992367 266 0
NRSF mAbJurkat 64978171 64978491 320 0
Oct1 H2O2-HelaGSE14283 64983039 64983076 37 0
Oct1 HelaGSE14283 64970199 64970229 30 0
Oct1 HelaGSE14283 64983039 64983073 34 0
P300 T30-glioblastomaGSE21026 64973273 64974979 1706 0
RARA MCF7GSE15244 64970061 64970304 243 0
RARA MCF7GSE15244 64970717 64970971 254 0
TFAP2C MCF7GSE21234 64970154 64970762 608 0
Validated miRNA targets Top
Cis-Nats regulation Top

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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