AutismKB 2.0

Annotation Detail for TOM1L1


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Basic Information Top
Gene Symbol:TOM1L1 ( OK/KNS-CL.3,SRCASM )
Gene Full Name: target of myb1 (chicken)-like 1
Band: 17q23.2
Quick LinksEntrez ID:10040; OMIM: 604701; Uniprot ID:TM1L1_HUMAN; ENSEMBL ID: ENSG00000141198; HGNC ID: 11983
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
314Phosphoserine.
321Phosphoserine.
323Phosphoserine.
425SH3-binding (By similarity).
460Phosphotyrosine (By similarity).
463SH2-binding (By similarity).
Location(AA) Modifications Resource
460Phosphotyrosine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
29Phosphothreonine(PKC)HMM predict
43N-linkedHMM predict
171O-linkedHMM predict
176O-linkedHMM predict
177O-linkedHMM predict
180O-linkedHMM predict
185O-linkedHMM predict
192N-linkedHMM predict
227Phosphothreonine(MAPK)HMM predict
305N-linkedHMM predict
307O-linkedHMM predict
308O-linkedHMM predict
308O-linkedHMM predict
323Phosphoserine(CDC2)HMM predict
323Phosphoserine(CDK)HMM predict
323PhosphoserineHMM predict
345N-linkedHMM predict
383Phosphoserine(IKK)HMM predict
385N-linkedHMM predict
392Phosphotyrosine(Syk)HMM predict
392Phosphotyrosine(Jak)HMM predict
411O-linkedHMM predict
417O-linkedHMM predict
418N-linkedHMM predict
432Phosphothreonine(PKC)HMM predict
442Phosphotyrosine(SRC)HMM predict
442Phosphotyrosine(Syk)HMM predict
455Phosphothreonine(PKC)HMM predict
460Phosphotyrosine(SRC)HMM predict
460Phosphotyrosine(INSR)HMM predict
460SulfotyrosineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_005486
  • Location:chr17 50333202-50394308
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 50332860 50333178 318 184
Myc hESGSE17917 50332920 50333273 353 106
Oct1 H2O2-HelaGSE14283 50332126 50332192 66 1044
hScc1 BcellGSE12603 50323415 50323748 333 9621
hScc1 BcellGSE12603 50332860 50333076 216 235
hScc1 CdLSGSE12603 50323415 50323960 545 9515
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 50380483 50381261 778 0
H3ac HepG2E 50333289 50334622 1333 0
Nanog ESGSE20650 50351885 50352182 297 0
Nanog hESGSE18292 50340922 50341250 328 0
P300 T30-glioblastomaGSE21026 50380477 50381481 1004 0
PHF8 HeLaGSE20725 50332866 50333847 981 0
PHF8 Hs68minusFBSGSE20725 50333004 50333814 810 0
STAT1 HeLaGSE12783 50369173 50370228 1055 0
Sox2 hESGSE18292 50351878 50352327 449 0
p130 shRbQuiescentGSE19898 50333120 50333870 750 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-1 hsa-mir-1-2 18 15685193
hsa-miR-1 hsa-mir-1-1 20 15685193
hsa-miR-124 hsa-mir-124-1 8 15685193
hsa-miR-124 hsa-mir-124-2 8 15685193
hsa-miR-124 hsa-mir-124-3 20 15685193
hsa-miR-373 hsa-mir-373 19 15685193
hsa-miR-373* hsa-mir-373 19 15685193
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
326 Unknown MicroArray miR-124 TOM1L1 n_a 15685193
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000141198 G1-to-S transition n_a n_a lymphocyte "benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
11402 mRNA TOM1L1 chr17 50333202 50394309 715 mRNA COX11 chr17 50384265 50401053Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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