AutismKB 2.0

Annotation Detail for NR1H3


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Basic Information Top
Gene Symbol:NR1H3 ( LXR-a,LXRA,RLD-1 )
Gene Full Name: nuclear receptor subfamily 1, group H, member 3
Band: 11p11.2
Quick LinksEntrez ID:10062; OMIM: 602423; Uniprot ID:NR1H3_HUMAN; ENSEMBL ID: ENSG00000025434; HGNC ID: 7966
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
30O-linkedHMM predict
30Phosphoserine(CK1)HMM predict
30Phosphoserine(ATM)HMM predict
49O-linkedHMM predict
85MethyllysineHMM predict
86MethyllysineHMM predict
198Phosphoserine(CDC2)HMM predict
198Phosphoserine(PKB)HMM predict
430LeucineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_005693
  • Location:chr11 47237308-47246971
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3ac HepG2E 47235911 47236611 700 1048
TFAP2C MCF7GSE21234 47235193 47236071 878 1677
p130 QuiescentGSE19898 47232687 47233029 342 4451
p130 QuiescentGSE19898 47235663 47235829 166 1563
p130 QuiescentGSE19898 47235886 47236310 424 1211
p130 SenescentGSE19898 47235607 47236189 582 1411
p130 shRbSenescentGSE19898 47235592 47235924 332 1551
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 47246625 47247401 776 42
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 47237692 47237880 188 0
CTCF CD4SISSRdata 47237692 47237880 188 0
Fos K562GSE19551 47243365 47243751 386 0
H3ac HepG2E 47237210 47237409 199 0
RARG MCF7GSE15244 47246503 47247328 825 0
hScc1 BcellGSE12603 47237210 47238089 879 0
hScc1 BcellGSE12603 47245945 47246202 257 0
hScc1 CdLSGSE12603 47237210 47238089 879 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-613 hsa-mir-613 12 21310851
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018