AutismKB 2.0

Annotation Detail for PTPRU


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:PTPRU ( FLJ37530,FMI,GLEPP1,PCP-2,PTP,PTP-J,PTP-PI,PTPPSI,PTPRO,PTPU2,R-PTP-PSI,hPTP-J )
Gene Full Name: protein tyrosine phosphatase, receptor type, U
Band: 1p35.3
Quick LinksEntrez ID:10076; OMIM: 602454; Uniprot ID:PTPRU_HUMAN; ENSEMBL ID: ENSG00000060656; HGNC ID: 9683
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
75N-linked (GlcNAc...) (Potential).
410N-linked (GlcNAc...) (Potential).
685N-linked (GlcNAc...) (Potential).
848Phosphoserine.
853Phosphoserine.
Location(AA) Modifications Resource
75N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
95N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
133N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
204N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
405N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
427N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
543N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
581N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
679N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
46Phosphotyrosine(Syk)HMM predict
46SulfotyrosineHMM predict
75N-linkedHMM predict
77Phosphoserine(ATM)HMM predict
95N-linkedHMM predict
133N-linkedHMM predict
172Phosphotyrosine(INSR)HMM predict
172Phosphotyrosine(Syk)HMM predict
259PhosphotyrosineHMM predict
297Phosphotyrosine(Jak)HMM predict
396Phosphothreonine(PKC)HMM predict
405N-linkedHMM predict
427N-linkedHMM predict
524Phosphoserine(CK2)HMM predict
537Phosphothreonine(PKC)HMM predict
543N-linkedHMM predict
558Phosphotyrosine(Jak)HMM predict
580O-linkedHMM predict
581N-linkedHMM predict
589SulfotyrosineHMM predict
589Phosphotyrosine(Syk)HMM predict
594Phosphoserine(MAPK)HMM predict
648MethylarginineHMM predict
679N-linkedHMM predict
771N-linkedHMM predict
793Phosphoserine(IKK)HMM predict
816Phosphotyrosine(Syk)HMM predict
837Phosphoserine(CDC2)HMM predict
882Phosphotyrosine(EGFR)HMM predict
993Phosphotyrosine(INSR)HMM predict
993Phosphotyrosine(Syk)HMM predict
1057Phosphoserine(PKG)HMM predict
1058Phosphothreonine(MAPK)HMM predict
1155Phosphoserine(IKK)HMM predict
1156N-linkedHMM predict
1158Phosphoserine(CK1)HMM predict
1158Phosphoserine(ATM)HMM predict
1216Phosphotyrosine(INSR)HMM predict
1264N-linkedHMM predict
1267N-linkedHMM predict
1284Phosphotyrosine(INSR)HMM predict
1284Phosphotyrosine(SRC)HMM predict
1398Phosphothreonine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_133178
  • Location:chr1 29435633-29525901
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 29435438 29435674 236 78
CTCF CD4SISSRdata 29435438 29435674 236 78
p130 shRbSenescentGSE19898 29435250 29435500 250 259
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 29531591 29531878 287 5833
CTCF G2GSE9613 29541495 29541814 319 15753
hScc1 BcellGSE12603 29526665 29526832 167 847
hScc1 BcellGSE12603 29531591 29531833 242 5811
hScc1 BcellGSE12603 29542995 29543255 260 17224
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 29447359 29449444 2085 0
CBP T30-glioblastomaGSE21026 29448224 29448789 565 0
CTCF CD4GSE12889 29445026 29445154 128 0
CTCF CD4SISSRdata 29445026 29445154 128 0
CTCF JurkatGSE12889 29444866 29445128 262 0
CTCF G2GSE9613 29435318 29436589 1271 0
CTCF G2GSE9613 29444806 29445280 474 0
CTCF G2GSE9613 29450384 29450558 174 0
CTCF G2GSE9613 29458795 29459161 366 0
CTCF G2GSE9613 29484931 29485281 350 0
CTCF G2GSE9613 29489146 29489302 156 0
CTCF G2GSE9613 29504594 29505468 874 0
CTCF G2GSE9613 29519468 29519961 493 0
CTCF G2GSE9613 29521454 29521662 208 0
CTCF G2GSE9613 29525601 29525916 315 0
FOXA1 MCF7GSE15244 29435804 29436623 819 0
FOXA1 MCF7GSE15244 29470160 29471426 1266 0
H3ac HepG2E 29435832 29436623 791 0
H3ac HepG2E 29443380 29444479 1099 0
Oct1 H2O2-HelaGSE14283 29516917 29516953 36 0
Oct1 H2O2-HelaGSE14283 29521172 29521202 30 0
Oct1 HelaGSE14283 29521136 29521199 63 0
P300 T0-glioblastomaGSE21026 29470604 29471359 755 0
P300 T30-glioblastomaGSE21026 29447958 29448962 1004 0
RARA MCF7GSE15244 29457579 29458279 700 0
RARA MCF7GSE15244 29470160 29471426 1266 0
RARG MCF7GSE15244 29457714 29458243 529 0
Rb GrowingGSE19898 29436127 29436436 309 0
SRF GMOGSE8489 29435940 29436623 683 0
SRF HepG2GSE8489 29435804 29436623 819 0
TAF HelaGSE8489 29435768 29436379 611 0
TFAP2C MCF7GSE21234 29438069 29438977 908 0
TFAP2C MCF7GSE21234 29470735 29471257 522 0
hScc1 BcellGSE12603 29435318 29436418 1100 0
hScc1 BcellGSE12603 29448039 29448506 467 0
hScc1 BcellGSE12603 29481760 29482683 923 0
hScc1 BcellGSE12603 29505824 29506585 761 0
hScc1 BcellGSE12603 29519637 29519961 324 0
hScc1 CdLSGSE12603 29435318 29436589 1271 0
p130 shRbQuiescentGSE19898 29435960 29436609 649 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-17 hsa-mir-17 13 18644370
hsa-miR-17 hsa-mir-17 13 18644370
hsa-miR-17* hsa-mir-17 13 18644370
hsa-miR-17* hsa-mir-17 13 18644370
hsa-miR-92a hsa-mir-92a-1 13 18644370
hsa-miR-92a hsa-mir-92a-2 X 18644370
hsa-miR-92a hsa-mir-92a-1 13 18644370
hsa-miR-92a hsa-mir-92a-2 X 18644370
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved