Annotation Detail for RASGRP1

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Basic Information Top

Gene Symbol:	RASGRP1 ( CALDAG-GEFI,CALDAG-GEFII,MGC129998,MGC129999,RASGRP,V,hRasGRP1 )
Gene Full Name:	RAS guanyl releasing protein 1 (calcium and DAG-regulated)
Band:	15q14
Quick Links	Entrez ID:10125; OMIM: 603962; Uniprot ID:GRP1_HUMAN; ENSEMBL ID: ENSG00000172575; HGNC ID: 9878
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:2 results
Experimental PTM Sites from dbPTM:0 results
Predicted PTM Sites by profile HMM from dbPTM:0 results

Location(AA)	Modification
184	Phosphothreonine; by PKC.
694	Phosphoserine.

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_005739
Location:chr15 36567597-36644223
strand:-

Upstream the gene:2 results
Downstream the gene:0 results
Inside the gene:10 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	G2	GSE9613	36643903	36644757	854	107
Sox2	hES	GSE18292	36656952	36657184	232	12845

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
ER	Fulvestrant-MCF7	GSE14664	36604646	36604686	40	0
Myc	K562	GSE19551	36627057	36627402	345	0
Oct1	Hela	GSE14283	36579726	36579759	33	0
Oct1	Hela	GSE14283	36584445	36584488	43	0
Oct1	Hela	GSE14283	36604653	36604687	34	0
Oct1	Hela	GSE14283	36628497	36628536	39	0
Rb	Growing	GSE19898	36635648	36635859	211	0
Rb	Quiescent	GSE19898	36635608	36635853	245	0
Rb	Senescent	GSE19898	36635521	36635800	279	0
hScc1	Bcell	GSE12603	36643472	36644714	1242	0

Validated miRNA targets

miR Walk:4 results
Tarbase V5.0:0 results

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-miR-148a	hsa-mir-148a	7	20483747
hsa-miR-148a*	hsa-mir-148a	7	20483747
hsa-miR-21	hsa-mir-21	17	20483747
hsa-miR-21*	hsa-mir-21	17	20483747

Cis-Nats regulation

Cluster ID	Plue Type	Plus Gene Name	Plus Chromosome	Plus Start	Plus End	Overlap Length	Minus Type	Minus Gene Name	Minus Chromosome	Minus Star	Minus End	Type
8646	mRNA		chr15	36582345	36584468	105	mRNA	RASGRP1	chr15	36567597	36644224	Sense/Antisense (SA) pairs

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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