AutismKB 2.0

Annotation Detail for LRPPRC


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Basic Information Top
Gene Symbol:LRPPRC ( CLONE-23970,GP130,LRP130,LSFC )
Gene Full Name: leucine-rich PPR-motif containing
Band: 2p21
Quick LinksEntrez ID:10128; OMIM: 607544; Uniprot ID:LPPRC_HUMAN; ENSEMBL ID: ENSG00000138095; HGNC ID: 15714
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
155N6-acetyllysine.
187N6-acetyllysine.
292N6-acetyllysine.
613N6-acetyllysine.
726N6-acetyllysine.
750N6-acetyllysine.
864N6-acetyllysine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
168Phosphothreonine(PKC)HMM predict
190Phosphoserine(CDK)HMM predict
196Phosphotyrosine(Jak)HMM predict
196Phosphotyrosine(INSR)HMM predict
264Phosphothreonine(MAPK)HMM predict
297N-linkedHMM predict
356Phosphotyrosine(Syk)HMM predict
387Phosphoserine(ATM)HMM predict
472Phosphoserine(CK1)HMM predict
541Phosphoserine(CK1)HMM predict
683Phosphothreonine(PKC)HMM predict
871Phosphothreonine(PKA)HMM predict
901Phosphoserine(CK1)HMM predict
903N-linkedHMM predict
904Phosphoserine(CK1)HMM predict
905Phosphoserine(CDC2)HMM predict
906O-linkedHMM predict
908Phosphoserine(IKK)HMM predict
922S-palmitoylHMM predict
1005Phosphothreonine(PKC)HMM predict
1015Phosphothreonine(MAPK)HMM predict
1182Phosphothreonine(PKC)HMM predict
1200Phosphotyrosine(EGFR)HMM predict
1240Phosphoserine(PKG)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_133259
  • Location:chr2 43968391-44076647
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 44076235 44077260 1025 100
H3ac HepG2E 44076614 44077228 614 274
HIF1 HypoHepG2 44076501 44077391 890 299
NRSF mAbJurkat 44092277 44092634 357 15808
NRSF mAbJurkat 44092972 44093179 207 16428
NRSF mAbJurkat 44093562 44093765 203 17016
NRSF mAbJurkat 44094478 44096131 1653 18657
NRSF-mono JurkatQuESTdata 44095086 44095335 249 18563
Oct1 HelaGSE14283 44082826 44082859 33 6195
P300 T0-glioblastomaGSE21026 44076362 44077407 1045 237
P300 T30-glioblastomaGSE21026 44076075 44077309 1234 45
PHF8 293TGSE20725 44076041 44077482 1441 114
PHF8 Hs68minusFBSGSE20725 44076288 44077475 1187 234
USF1 HepG2E 44076501 44077318 817 262
USF2 HepG2E 44076501 44077266 765 236
p130 SenescentGSE19898 44076511 44076791 280 4
p130 SenescentGSE19898 44076956 44077312 356 487
p130 shRbSenescentGSE19898 44076532 44076792 260 15
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 43965169 43965663 494 2976
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 44031092 44031405 313 0
CTCF G2GSE9613 44076288 44076706 418 0
FOXA1 MCF7GSE15244 43978999 43979996 997 0
FOXA1 MCF7GSE15244 43987170 43987701 531 0
FoxA1 MCF7MACSdata 43979623 43979928 305 0
H3K4me2 HCT116GSE10453 44075280 44076036 756 0
H3K4me3 colorectalcancer 44074825 44076216 1391 0
H3ac HepG2E 44075001 44076252 1251 0
Myc K562GSE19551 44065962 44066384 422 0
Oct1 HelaGSE14283 44054614 44054648 34 0
PHF8 HeLaGSE20725 44075775 44077173 1398 0
TAF HelaGSE8489 44075403 44076150 747 0
TAF k562GSE8489 44072739 44073728 989 0
TAF k562GSE8489 44074272 44076216 1944 0
USF1 HepG2E 44075206 44076252 1046 0
USF2 HepG2E 44075206 44076216 1010 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-21 hsa-mir-21 17 19672202
hsa-miR-21* hsa-mir-21 17 19672202
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
14208 HTC chr2 44134774 44135408 21 mRNA LRPPRC chr2 44026537 44134795Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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