AutismKB 2.0

Annotation Detail for SLC25A13


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Basic Information Top
Gene Symbol:SLC25A13 ( ARALAR2,CITRIN,CTLN2 )
Gene Full Name: solute carrier family 25, member 13 (citrin)
Band: 7q21.3
Quick LinksEntrez ID:10165; OMIM: 603859; Uniprot ID:CMC2_HUMAN; ENSEMBL ID: ENSG00000004864; HGNC ID: 10983
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
484N6-acetyllysine.
Location(AA) Modifications Resource
484N6-acetyllysine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
51Phosphoserine(ATM)HMM predict
210O-linkedHMM predict
286Phosphothreonine(PKC)HMM predict
590Phosphoserine(CDC2)HMM predict
668O-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_014251
  • Location:chr7 95587468-95789340
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 95794769 95795582 813 5835
FOXA1 MCF7GSE15244 95798432 95799113 681 9432
Oct1 HelaGSE14283 95795579 95795608 29 6253
RARA MCF7GSE15244 95794769 95795582 813 5835
Rb QuiescentGSE19898 95789515 95789733 218 284
USF1 HepG2E 95789528 95790368 840 608
USF1 HepG2E 95791324 95791572 248 2108
USF2 HepG2E 95789637 95790299 662 628
p130 SenescentGSE19898 95789507 95789742 235 284
p130 shRbQuiescentGSE19898 95789316 95789736 420 186
p130 shRbSenescentGSE19898 95789309 95789583 274 106
p63 keratinocytesGSE17611 95797048 95797911 863 8139
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 95584590 95585139 549 2604
CTCF G2GSE9613 95585796 95586120 324 1511
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 95640968 95641125 157 0
CTCF G2GSE9613 95642105 95642590 485 0
CTCF G2GSE9613 95655400 95655585 185 0
CTCF G2GSE9613 95752183 95752327 144 0
CTCF G2GSE9613 95788789 95789562 773 0
ER E2-MCF7GSE14664 95639505 95639546 41 0
ER E2-MCF7GSE14664 95718719 95718759 40 0
ER Fulvestrant-MCF7GSE14664 95639505 95639540 35 0
ER MCF7GSE19013 95642226 95642721 495 0
FOXA1 MCF7GSE15244 95770385 95771563 1178 0
Fos K562GSE19551 95703295 95704422 1127 0
FoxA1 MCF7MACSdata 95770314 95770762 448 0
H3K4me3 colorectalcancer 95787919 95788539 620 0
KLF4 hESGSE17917 95788394 95788552 158 0
Nanog ESGSE20650 95610585 95611617 1032 0
Nanog hESGSE18292 95593743 95593937 194 0
Nanog hESGSE18292 95610461 95611752 1291 0
Nanog hESGSE18292 95665369 95665882 513 0
Nanog hESGSE18292 95752960 95753233 273 0
Oct1 H2O2-HelaGSE14283 95662335 95662363 28 0
Oct1 H2O2-HelaGSE14283 95669264 95669300 36 0
Oct1 H2O2-HelaGSE14283 95680463 95680500 37 0
Oct1 H2O2-HelaGSE14283 95710431 95710481 50 0
Oct1 HelaGSE14283 95639508 95639540 32 0
Oct1 HelaGSE14283 95669265 95669301 36 0
Oct1 HelaGSE14283 95678038 95678065 27 0
Oct1 HelaGSE14283 95680466 95680497 31 0
Oct1 HelaGSE14283 95710432 95710481 49 0
Oct1 HelaGSE14283 95718724 95718752 28 0
TFAP2C MCF7GSE21234 95602284 95602930 646 0
TFAP2C MCF7GSE21234 95645740 95646260 520 0
TFAP2C MCF7GSE21234 95781515 95782072 557 0
hScc1 BcellGSE12603 95788820 95789260 440 0
p130 shRbQuiescentGSE19898 95788659 95789180 521 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7b hsa-let-7b 22 18668040
hsa-let-7b* hsa-let-7b 22 18668040
hsa-miR-1 hsa-mir-1-2 18 18668040
hsa-miR-1 hsa-mir-1-1 20 18668040
hsa-miR-155 hsa-mir-155 21 18668040
hsa-miR-155* hsa-mir-155 21 18668040
hsa-miR-16 hsa-mir-16-1 13 18668040
hsa-miR-16 hsa-mir-16-2 3 18668040
hsa-miR-30a hsa-mir-30a 6 18668040
hsa-miR-30a* hsa-mir-30a 6 18668040
hsa-miR-30b hsa-mir-30b 8 18668040
hsa-miR-30b* hsa-mir-30b 8 18668040
hsa-miR-30c hsa-mir-30c-2 6 18668040
hsa-miR-30c hsa-mir-30c-1 1 18668040
hsa-miR-30c-1* hsa-mir-30c-1 1 18668040
hsa-miR-30c-2* hsa-mir-30c-2 6 18668040
hsa-miR-30d hsa-mir-30d 8 18668040
hsa-miR-30d* hsa-mir-30d 8 18668040
hsa-miR-30e hsa-mir-30e 1 18668040
hsa-miR-30e* hsa-mir-30e 1 18668040
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
894 Unknown pSILAC let-7b SLC25A13 down 50-25% 18668040
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000004864 n_a n_a n_a "lymphocyte, muscle cell" "benign tumour, malignant tumour, carcinoma, sarcoma"
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018