AutismKB 2.0

Annotation Detail for SORBS3


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SORBS3 ( SCAM-1,SCAM1,SH3D4,VINEXIN )
Gene Full Name: sorbin and SH3 domain containing 3
Band: 8p21.3
Quick LinksEntrez ID:10174; OMIM: 610795; Uniprot ID:VINEX_HUMAN; ENSEMBL ID: ENSG00000120896; HGNC ID: 30907
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
217Phosphoserine.
218Phosphothreonine.
348Phosphoserine.
395Phosphoserine.
529Phosphothreonine.
530Phosphoserine.
545Phosphoserine.
551Phosphoserine.
563Phosphoserine.
Location(AA) Modifications Resource
348Phosphoserine.Swiss-Prot 53.0
530Phosphoserine.Swiss-Prot 53.0
545Phosphoserine.Swiss-Prot 53.0
551Phosphoserine.Swiss-Prot 53.0
563Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
64Phosphothreonine(MAPK)HMM predict
64Phosphothreonine(CDK)HMM predict
70Phosphoserine(ATM)HMM predict
91O-linkedHMM predict
97Phosphoserine(PKC)HMM predict
102N-linkedHMM predict
268Phosphoserine(ATM)HMM predict
299Phosphoserine(CDC2)HMM predict
299O-linkedHMM predict
302Phosphoserine(IKK)HMM predict
303Phosphoserine(CDC2)HMM predict
303Phosphoserine(CDK)HMM predict
320O-linkedHMM predict
331Phosphotyrosine(Jak)HMM predict
339Phosphoserine(ATM)HMM predict
339Phosphoserine(CDC2)HMM predict
358Phosphotyrosine(EGFR)HMM predict
373Phosphoserine(CDC2)HMM predict
451Phosphotyrosine(SRC)HMM predict
530Phosphoserine(MAPK)HMM predict
530Phosphoserine(CDC2)HMM predict
544Phosphoserine(PKB)HMM predict
545Phosphoserine(CDK)HMM predict
545Phosphoserine(MAPK)HMM predict
545Phosphoserine(CDC2)HMM predict
551Phosphoserine(IKK)HMM predict
563Phosphoserine(CDC2)HMM predict
573O-linkedHMM predict
606Phosphoserine(CDC2)HMM predict
608N-linkedHMM predict
657Phosphothreonine(PKC)HMM predict
657Phosphothreonine(PKA)HMM predict
667Phosphotyrosine(Abl)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001018003
  • Location:chr8 22479159-22488951
  • strand:+
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 22489181 22489333 152 306
GATA3 MCF7GSE15244 22489110 22489333 223 270
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 22487783 22488301 518 0
CTCF CD4SISSRdata 22487783 22488301 518 0
CTCF G2GSE9613 22479439 22480684 1245 0
CTCF G2GSE9613 22483618 22483857 239 0
CTCF G2GSE9613 22485663 22486568 905 0
CTCF G2GSE9613 22487520 22488378 858 0
NRSF pAbJurkat 22484397 22484838 441 0
STAT1 IFNSISSRdata 22487828 22488359 531 0
hScc1 BcellGSE12603 22484205 22484699 494 0
hScc1 BcellGSE12603 22487637 22488502 865 0
hScc1 CdLSGSE12603 22487637 22488347 710 0
hScc1 G2GSE9613 22487865 22488378 513 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018