AutismKB 2.0

Annotation Detail for CDK5


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:CDK5 ( PSSALRE )
Gene Full Name: cyclin-dependent kinase 5
Band: 7q36.1
Quick LinksEntrez ID:1020; OMIM: 123831; Uniprot ID:CDK5_HUMAN; ENSEMBL ID: ENSG00000164885; HGNC ID: 1774
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
14Phosphothreonine.
15Phosphotyrosine; by ABL1.
17Phosphothreonine.
46Phosphoserine.
56N6-acetyllysine.
72Phosphoserine.
159Phosphoserine (By similarity).
239Phosphotyrosine.
Location(AA) Modifications Resource
14Phosphothreonine (By similarity).Swiss-Prot 53.0
15Phosphotyrosine (by ABL1) (Bysimilarity).Swiss-Prot 53.0
15Phosphotyrosine (Abl)Phospho.ELM 6.0
159Phosphoserine (By similarity).Swiss-Prot 53.0
159Phosphoserine (CK1
Location(AA) Modification Resource
15Phosphotyrosine(EGFR)HMM predict
15Phosphotyrosine(SRC)HMM predict
77Phosphothreonine(PKC)HMM predict
256N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004935
  • Location:chr7 150381831-150385928
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 150386359 150386719 360 611
ETS1 JurkatGSE17954 150385420 150387476 2056 520
P300 T30-glioblastomaGSE21026 150385549 150387695 2146 694
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 150384847 150385771 924 0
FOXA1 MCF7GSE15244 150384601 150385903 1302 0
H3ac HepG2E 150384601 150385771 1170 0
NRSF mAbJurkat 150382823 150384243 1420 0
NRSF mAbJurkat 150384985 150385703 718 0
TFAP2C MCF7GSE21234 150384494 150385378 884 0
hScc1 BcellGSE12603 150384051 150384278 227 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018