AutismKB 2.0

Annotation Detail for TRIB1


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Basic Information Top
Gene Symbol:TRIB1 ( C8FW,GIG2,SKIP1,TRB1 )
Gene Full Name: tribbles homolog 1 (Drosophila)
Band: 8q24.13
Quick LinksEntrez ID:10221; OMIM: 609461; Uniprot ID:TRIB1_HUMAN; ENSEMBL ID: ENSG00000173334; HGNC ID: 16891
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
11Phosphoserine(IKK)HMM predict
11O-linkedHMM predict
14Phosphoserine(ATM)HMM predict
61Phosphoserine(CDC2)HMM predict
61O-linkedHMM predict
65Phosphoserine(IKK)HMM predict
68O-linkedHMM predict
68Phosphoserine(MAPK)HMM predict
68Phosphoserine(CDK)HMM predict
68Phosphoserine(ATM)HMM predict
82O-linkedHMM predict
84O-linkedHMM predict
142N-linkedHMM predict
240Phosphoserine(CK1)HMM predict
248Phosphotyrosine(INSR)HMM predict
255N-linkedHMM predict
353Phosphothreonine(CK2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_025195
  • Location:chr8 126511744-126519823
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER E2-MCF7GSE14664 126492732 126492779 47 18989
ER E2-MCF7GSE14664 126494435 126494506 71 17274
ER E2-MCF7GSE14664 126497847 126497898 51 13872
ER E2-MCF7GSE14664 126499519 126499605 86 12183
ER E2-MCF7GSE14664 126501224 126501309 85 10478
ER E2-MCF7GSE14664 126506334 126506441 107 5357
ER E2-MCF7GSE14664 126508017 126508123 106 3675
ER Fulvestrant-MCF7GSE14664 126492719 126492824 105 18973
ER Fulvestrant-MCF7GSE14664 126494438 126494476 38 17288
ER Fulvestrant-MCF7GSE14664 126499534 126499611 77 12172
ER Fulvestrant-MCF7GSE14664 126501189 126501231 42 10535
FOXA1 DLD1GSE12801 126510812 126512133 1321 272
FOXA1 MCF7GSE15244 126491938 126492519 581 19516
FOXA1 MCF7GSE15244 126507192 126507402 210 4448
Fos K562GSE19551 126491978 126492427 449 19542
Fos K562GSE19551 126510868 126512112 1244 255
FoxA1 MCF7MACSdata 126511420 126511871 451 99
GATA3 MCF7GSE15244 126502640 126503000 360 8925
H3ac HepG2E 126493570 126493947 377 17986
H3ac HepG2E 126499189 126499658 469 12321
H3ac HepG2E 126509414 126509738 324 2169
NRSF pAbJurkat 126511208 126512235 1027 23
Oct1 HelaGSE14283 126496121 126496213 92 15578
Oct1 HelaGSE14283 126497804 126497920 116 13883
Oct1 HelaGSE14283 126499565 126499613 48 12156
Oct1 HelaGSE14283 126501216 126501275 59 10499
Oct1 HelaGSE14283 126502905 126502994 89 8795
Oct1 HelaGSE14283 126508017 126508122 105 3675
Oct1 HelaGSE14283 126509737 126509810 73 1971
RARA MCF7GSE15244 126491964 126492417 453 19554
RARG MCF7GSE15244 126491738 126492341 603 19705
RARG MCF7GSE15244 126493570 126494325 755 17797
Rb SenescentGSE19898 126491881 126492383 502 19613
TFAP2C MCF7GSE21234 126510366 126511930 1564 597
p130 QuiescentGSE19898 126491986 126492181 195 19661
p130 SenescentGSE19898 126491939 126492447 508 19552
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 126533283 126533943 660 13790
P300 T30-glioblastomaGSE21026 126533075 126534170 1095 13799
RARA MCF7GSE15244 126521200 126522338 1138 1946
RARA MCF7GSE15244 126533283 126533943 660 13790
RARA MCF7GSE15244 126536553 126537209 656 17058
RARG MCF7GSE15244 126533283 126534050 767 13843
TFAP2C MCF7GSE21234 126533191 126534236 1045 13890
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 126511478 126512097 619 0
FOXA1 MCF7GSE15244 126513079 126514221 1142 0
FOXA1 MCF7GSE15244 126514628 126518002 3374 0
H3K4me3 colorectalcancer 126513156 126513523 367 0
H3K4me3 colorectalcancer 126513871 126514194 323 0
H3ac HepG2E 126512888 126515859 2971 0
NFkBII GM15510GSE19485 126510619 126514673 4054 0
RARA MCF7GSE15244 126515383 126517475 2092 0
RARG MCF7GSE15244 126513156 126514131 975 0
RARG MCF7GSE15244 126514556 126517965 3409 0
TAF HelaGSE8489 126513117 126513871 754 0
hScc1 BcellGSE12603 126511050 126513831 2781 0
hScc1 CdLSGSE12603 126512477 126513941 1464 0
hScc1 G2GSE9613 126511793 126513798 2005 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-122 hsa-mir-122 18 19296470
hsa-miR-122* hsa-mir-122 18 19296470
hsa-miR-204 hsa-mir-204 9 20691260
hsa-miR-27a hsa-mir-27a 19 21149577
hsa-miR-27a* hsa-mir-27a 19 21149577
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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