AutismKB 2.0

Annotation Detail for MSLN


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Basic Information Top
Gene Symbol:MSLN ( MPF,SMRP )
Gene Full Name: mesothelin
Band: 16p13.3
Quick LinksEntrez ID:10232; OMIM: 601051; Uniprot ID:MSLN_HUMAN; ENSEMBL ID: ENSG00000102854; HGNC ID: 7371
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
57N-linked (GlcNAc...) (Probable).
388N-linked (GlcNAc...) (Potential).
496N-linked (GlcNAc...) (Potential).
523N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
57N-linked (GlcNAc...) (Probable).Swiss-Prot 53.0
388N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
496N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
523N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
606GPI-anchor amidated serine (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
57N-linkedHMM predict
210Phosphoserine(IKK)HMM predict
234Phosphotyrosine(Abl)HMM predict
234Phosphotyrosine(INSR)HMM predict
238O-linkedHMM predict
241Phosphoserine(IKK)HMM predict
280Phosphoserine(PKC)HMM predict
280PhosphoserineHMM predict
280Phosphoserine(IKK)HMM predict
360SulfotyrosineHMM predict
374Phosphotyrosine(Jak)HMM predict
388N-linkedHMM predict
394Phosphothreonine(PKC)HMM predict
453Phosphoserine(MAPK)HMM predict
459Phosphoserine(ATM)HMM predict
459O-linkedHMM predict
496N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_005823
  • Location:chr16 751133-758865
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER Breast-CancerGSE22609 743455 743835 380 7489
ER MCF7GSE19013 743286 743983 697 7499
TFAP2C MCF7GSE21234 750569 751035 466 332
hScc1 BcellGSE12603 750037 750375 338 928
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 752101 752819 718 0
CTCF G2GSE9613 754209 755531 1322 0
CTCF G2GSE9613 758153 758614 461 0
TFAP2C MCF7GSE21234 758583 759047 464 0
hScc1 BcellGSE12603 752006 752360 354 0
hScc1 BcellGSE12603 754640 756227 1587 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018