AutismKB 2.0

Annotation Detail for CDK8


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Basic Information Top
Gene Symbol:CDK8 ( K35,MGC126074,MGC126075 )
Gene Full Name: cyclin-dependent kinase 8
Band: 13q12.13
Quick LinksEntrez ID:1024; OMIM: 603184; Uniprot ID:CDK8_HUMAN; ENSEMBL ID: ENSG00000132964; HGNC ID: 1779
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
410Phosphothreonine.
413Phosphoserine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
10Phosphoserine(PKG)HMM predict
29MethylarginineHMM predict
31Phosphothreonine(PKC)HMM predict
41MethyllysineHMM predict
44MethyllysineHMM predict
49Phosphotyrosine(INSR)HMM predict
182Phosphoserine(CDC2)HMM predict
290N-linkedHMM predict
326Phosphoserine(CK2)HMM predict
380N-linkedHMM predict
383N-linkedHMM predict
394O-linkedHMM predict
437O-linkedHMM predict
439Phosphoserine(ATM)HMM predict
439O-linkedHMM predict
447Phosphotyrosine(Jak)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001260
  • Location:chr13 25726755-25876568
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 25726105 25726855 750 276
ETS1 JurkatGSE17954 25725437 25726659 1222 708
Myc K562GSE19551 25719744 25720210 466 6779
P300 T30-glioblastomaGSE21026 25725708 25726618 910 593
PHF8 HeLaGSE20725 25725837 25726772 935 451
Pol2 GM12878GSE19551 25726061 25726521 460 465
Rb GrowingGSE19898 25718397 25718575 178 8270
TAFII hESGSE17917 25725902 25726616 714 497
USF1 HepG2E 25712597 25712900 303 14007
hScc1 BcellGSE12603 25726066 25727137 1071 154
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 25882666 25882840 174 6185
CTCF G2GSE9613 25896396 25896707 311 19983
Nanog hESGSE18292 25895782 25896023 241 19334
hScc1 BcellGSE12603 25878999 25879609 610 2736
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Fos K562GSE19551 25772371 25772630 259 0
H3ac HepG2E 25726994 25727902 908 0
Nanog hESGSE18292 25820979 25821514 535 0
p63 keratinocytesGSE17611 25779554 25780513 959 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-26a hsa-mir-26a-1 3 18713946
hsa-miR-26a hsa-mir-26a-2 12 18713946
hsa-miR-26a-1* hsa-mir-26a-1 3 18713946
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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