Annotation Detail for CDKN1A

View Evidences	View Variants	View Annotations

Basic Information Top

Gene Symbol:	CDKN1A ( CAP20,CDKN1,CIP1,MDA-6,P21,SDI1,WAF1,p21CIP1 )
Gene Full Name:	cyclin-dependent kinase inhibitor 1A (p21, Cip1)
Band:	6p21.2
Quick Links	Entrez ID:1026; OMIM: 116899; Uniprot ID:CDN1A_HUMAN; ENSEMBL ID: ENSG00000124762; HGNC ID: 1784
Relate to Another Database:	SFARIGene; denovo-db

General

Expression

Regulation

Pathways, Diseases and Drugs

PTM

TF binding site

miRNA targets

Cis-NATs

Post Translation Modification

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PTM Sites from Uniprot:8 results
Experimental PTM Sites from dbPTM:10 results
Predicted PTM Sites by profile HMM from dbPTM:7 results

Location(AA)	Modification
2	N-acetylserine.
114	Phosphoserine; by GSK3-beta.
130	Phosphoserine.
145	Phosphothreonine; by PKA and PKB/AKT1.
146	Phosphoserine; by PKC.
156	Nuclear localization signal (Potential).
160	Phosphoserine; by PKC; in vitro.
164	PIP-box K+4 motif.

Location(AA)	Modifications	Resource
2	N-acetylserine.	Swiss-Prot 53.0
56	Phosphothreonine (GSK-3beta;MA)	Phospho.ELM 6.0
129	Phosphoserine (CDK2;MAPK
130	Phosphoserine.	Swiss-Prot 53.0
144	Phosphothreonine (DAPK3;PKB
145	Phosphoserine (PKC alpha;PK)	Phospho.ELM 6.0
145	Phosphothreonine (by PKA and PKB/AKT1).	Swiss-Prot 53.0
146	Phosphoserine (by PKC).	Swiss-Prot 53.0
152	Phosphoserine (DYRK1B)	Phospho.ELM 6.0
160	Phosphoserine; by PKC; in vitro.	Swiss-Prot 53.0

Location(AA)	Modification	Resource
86	Methylarginine	HMM predict
97	Phosphothreonine(PKA)	HMM predict
137	Phosphoserine(ATM)	HMM predict
145	Phosphothreonine(PKA)	HMM predict
146	Phosphoserine(CAMK2)	HMM predict
146	Phosphoserine(PKB)	HMM predict
146	Phosphoserine(PKA)	HMM predict

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_000389
Location:chr6 36754464-36763085
strand:+

Upstream the gene:13 results
Downstream the gene:1 results
Inside the gene:27 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	G2	GSE9613	36736507	36736992	485	17715
H3K4me2	HCT116	GSE10453	36753245	36754003	758	841
H3ac	HepG2	E	36737062	36737629	567	17119
H3ac	HepG2	E	36739118	36739537	419	15137
H3ac	HepG2	E	36749944	36750320	376	4333
H3ac	HepG2	E	36751577	36754155	2578	1599
KLF4	hES	GSE17917	36736577	36736768	191	17792
P300	T30-glioblastoma	GSE21026	36742586	36743364	778	11490
USF2	HepG2	E	36753209	36754039	830	841
hScc1	Bcell	GSE12603	36736507	36737030	523	17696
hScc1	Bcell	GSE12603	36754370	36754541	171	9
p130	shRbSenescent	GSE19898	36752299	36752594	295	2018
p63	keratinocytes	GSE17611	36742414	36743437	1023	11539

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
ER	Fulvestrant-MCF7	GSE14664	36767644	36767696	52	4585

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length
CBP	Jurkat	GSE17954	36757930	36759588	1658
CTCF	CD4	GSE12889	36756143	36756487	344
CTCF	CD4	SISSRdata	36756143	36756487	344
CTCF	G2	GSE9613	36754075	36754991	916
CTCF	G2	GSE9613	36755964	36756869	905
CTCF	G2	GSE9613	36759340	36760349	1009
H3ac	HepG2	E	36754921	36756014	1093
Oct1	Hela	GSE14283	36755169	36755211	42
Pol2	GM12878	GSE19551	36753942	36756540	2598
RARA	MCF7	GSE15244	36758103	36758778	675
Rb	Growing	GSE19898	36756090	36756485	395
Rb	Quiescent	GSE19898	36755975	36756572	597
Rb	Senescent	GSE19898	36755892	36756839	947
Rb	shRbQuiescent	GSE19898	36755991	36756493	502
TFAP2C	MCF7	GSE21234	36756045	36756540	495
TFAP2C	MCF7	GSE21234	36758056	36758921	865
USF2	HepG2	E	36759340	36760349	1009
VDR	GM10855-Unstim	GSE22484	36750700	36765151	14451
VDR	GM10855-stim	GSE22484	36751449	36765153	13704
hScc1	Bcell	GSE12603	36755886	36756524	638
hScc1	CdLS	GSE12603	36755575	36756869	1294
hScc1	G2	GSE9613	36753976	36755100	1124
hScc1	G2	GSE9613	36755986	36756869	883
p130	Quiescent	GSE19898	36756042	36756606	564
p130	Senescent	GSE19898	36755938	36756722	784
p130	shRbQuiescent	GSE19898	36755936	36756542	606
p130	shRbSenescent	GSE19898	36755781	36756520	739

Validated miRNA targets

Top

miR Walk:395 results
Tarbase V5.0:5 results

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-let-7a	hsa-let-7a-1	9	19956384
hsa-let-7a	hsa-let-7a-2	11	19956384
hsa-let-7a	hsa-let-7a-3	22	19956384
hsa-let-7a	hsa-let-7a-1	9	19818775
hsa-let-7a	hsa-let-7a-2	11	19818775
hsa-let-7a	hsa-let-7a-3	22	19818775
hsa-let-7a	hsa-let-7a-1	9	18798260
hsa-let-7a	hsa-let-7a-2	11	18798260
hsa-let-7a	hsa-let-7a-3	22	18798260
hsa-let-7a*	hsa-let-7a-1	9	19956384
hsa-let-7a*	hsa-let-7a-3	22	19956384
hsa-let-7a*	hsa-let-7a-1	9	19818775
hsa-let-7a*	hsa-let-7a-3	22	19818775
hsa-let-7a*	hsa-let-7a-1	9	18798260
hsa-let-7a*	hsa-let-7a-3	22	18798260
hsa-let-7b	hsa-let-7b	22	19956384
hsa-let-7b	hsa-let-7b	22	19818775
hsa-let-7b	hsa-let-7b	22	18798260
hsa-let-7b*	hsa-let-7b	22	19956384
hsa-let-7b*	hsa-let-7b	22	19818775
hsa-let-7b*	hsa-let-7b	22	18798260
hsa-let-7c	hsa-let-7c	21	19956384
hsa-let-7c	hsa-let-7c	21	19818775
hsa-let-7c	hsa-let-7c	21	18798260
hsa-let-7c*	hsa-let-7c	21	19956384
hsa-let-7c*	hsa-let-7c	21	19818775
hsa-let-7c*	hsa-let-7c	21	18798260
hsa-let-7d	hsa-let-7d	9	20652617
hsa-let-7d	hsa-let-7d	9	19956384
hsa-let-7d	hsa-let-7d	9	19818775
hsa-let-7d	hsa-let-7d	9	18798260
hsa-let-7d*	hsa-let-7d	9	20652617
hsa-let-7d*	hsa-let-7d	9	19956384
hsa-let-7d*	hsa-let-7d	9	19818775
hsa-let-7d*	hsa-let-7d	9	18798260
hsa-let-7e	hsa-let-7e	19	19956384
hsa-let-7e	hsa-let-7e	19	19818775
hsa-let-7e	hsa-let-7e	19	18798260
hsa-let-7e*	hsa-let-7e	19	19956384
hsa-let-7e*	hsa-let-7e	19	19818775
hsa-let-7e*	hsa-let-7e	19	18798260
hsa-let-7f	hsa-let-7f-1	9	19956384
hsa-let-7f	hsa-let-7f-2	X	19956384
hsa-let-7f	hsa-let-7f-1	9	19818775
hsa-let-7f	hsa-let-7f-2	X	19818775
hsa-let-7f	hsa-let-7f-1	9	18798260
hsa-let-7f	hsa-let-7f-2	X	18798260
hsa-let-7f-1*	hsa-let-7f-1	9	19956384
hsa-let-7f-1*	hsa-let-7f-1	9	19818775
hsa-let-7f-1*	hsa-let-7f-1	9	18798260
hsa-let-7f-2*	hsa-let-7f-2	X	19956384
hsa-let-7f-2*	hsa-let-7f-2	X	19818775
hsa-let-7f-2*	hsa-let-7f-2	X	18798260
hsa-let-7g	hsa-let-7g	3	19956384
hsa-let-7g	hsa-let-7g	3	19818775
hsa-let-7g	hsa-let-7g	3	18798260
hsa-let-7g*	hsa-let-7g	3	19956384
hsa-let-7g*	hsa-let-7g	3	19818775
hsa-let-7g*	hsa-let-7g	3	18798260
hsa-let-7i	hsa-let-7i	12	19956384
hsa-let-7i	hsa-let-7i	12	19818775
hsa-let-7i	hsa-let-7i	12	18798260
hsa-let-7i*	hsa-let-7i	12	19956384
hsa-let-7i*	hsa-let-7i	12	19818775
hsa-let-7i*	hsa-let-7i	12	18798260
hsa-miR-1	hsa-mir-1-2	18	19229884
hsa-miR-1	hsa-mir-1-1	20	19229884
hsa-miR-1	hsa-mir-1-2	18	18676839
hsa-miR-1	hsa-mir-1-1	20	18676839
hsa-miR-106a	hsa-mir-106a	X	20089119
hsa-miR-106a	hsa-mir-106a	X	19782699
hsa-miR-106a	hsa-mir-106a	X	18212054
hsa-miR-106a*	hsa-mir-106a	X	20089119
hsa-miR-106a*	hsa-mir-106a	X	19782699
hsa-miR-106a*	hsa-mir-106a	X	18212054
hsa-miR-106b	hsa-mir-106b	7	21285944
hsa-miR-106b	hsa-mir-106b	7	21283757
hsa-miR-106b	hsa-mir-106b	7	21088000
hsa-miR-106b	hsa-mir-106b	7	20878953
hsa-miR-106b	hsa-mir-106b	7	20637509
hsa-miR-106b	hsa-mir-106b	7	20101223
hsa-miR-106b	hsa-mir-106b	7	19782699
hsa-miR-106b	hsa-mir-106b	7	19660235
hsa-miR-106b	hsa-mir-106b	7	19153141
hsa-miR-106b	hsa-mir-106b	7	18676839
hsa-miR-106b	hsa-mir-106b	7	18328430
hsa-miR-106b	hsa-mir-106b	7	18212054
hsa-miR-106b	hsa-mir-106b	7	19422085
hsa-miR-106b	hsa-mir-106b	7	20190813
hsa-miR-106b*	hsa-mir-106b	7	21285944
hsa-miR-106b*	hsa-mir-106b	7	21283757
hsa-miR-106b*	hsa-mir-106b	7	21088000
hsa-miR-106b*	hsa-mir-106b	7	20878953
hsa-miR-106b*	hsa-mir-106b	7	20637509
hsa-miR-106b*	hsa-mir-106b	7	20101223
hsa-miR-106b*	hsa-mir-106b	7	19782699
hsa-miR-106b*	hsa-mir-106b	7	19660235
hsa-miR-106b*	hsa-mir-106b	7	19153141
hsa-miR-106b*	hsa-mir-106b	7	18676839
hsa-miR-106b*	hsa-mir-106b	7	18328430
hsa-miR-106b*	hsa-mir-106b	7	18212054
hsa-miR-106b*	hsa-mir-106b	7	19422085
hsa-miR-106b*	hsa-mir-106b	7	20190813
hsa-miR-125a-3p	hsa-mir-125a	19	19950226
hsa-miR-125a-5p	hsa-mir-125a	19	19950226
hsa-miR-125a-5p	hsa-mir-125a	19	20190813
hsa-miR-125b	hsa-mir-125b-1	11	21118985
hsa-miR-125b	hsa-mir-125b-2	21	21118985
hsa-miR-125b	hsa-mir-125b-1	11	20827722
hsa-miR-125b	hsa-mir-125b-2	21	20827722
hsa-miR-126	hsa-mir-126	9	21148433
hsa-miR-126*	hsa-mir-126	9	21148433
hsa-miR-128	hsa-mir-128-1	2	19010882
hsa-miR-128	hsa-mir-128-2	3	19010882
hsa-miR-128	hsa-mir-128-1	2	18810376
hsa-miR-128	hsa-mir-128-2	3	18810376
hsa-miR-1285	hsa-mir-1285-1	7	20417621
hsa-miR-1285	hsa-mir-1285-2	2	20417621
hsa-miR-130b	hsa-mir-130b	22	20101223
hsa-miR-130b*	hsa-mir-130b	22	20101223
hsa-miR-132	hsa-mir-132	17	20190813
hsa-miR-132*	hsa-mir-132	17	20190813
hsa-miR-140-3p	hsa-mir-140	16	19734943
hsa-miR-140-3p	hsa-mir-140	16	19950226
hsa-miR-140-5p	hsa-mir-140	16	19734943
hsa-miR-140-5p	hsa-mir-140	16	19950226
hsa-miR-142-3p	hsa-mir-142	17	19229884
hsa-miR-143	hsa-mir-143	5	20089806
hsa-miR-143*	hsa-mir-143	5	20089806
hsa-miR-145	hsa-mir-145	5	20089806
hsa-miR-145	hsa-mir-145	5	20190813
hsa-miR-145*	hsa-mir-145	5	20089806
hsa-miR-145*	hsa-mir-145	5	20190813
hsa-miR-146a	hsa-mir-146a	5	20101223
hsa-miR-146a*	hsa-mir-146a	5	20101223
hsa-miR-146b-3p	hsa-mir-146b	10	20101223
hsa-miR-146b-3p	hsa-mir-146b	10	18798260
hsa-miR-146b-5p	hsa-mir-146b	10	20101223
hsa-miR-146b-5p	hsa-mir-146b	10	18798260
hsa-miR-149	hsa-mir-149	2	19950226
hsa-miR-149*	hsa-mir-149	2	19950226
hsa-miR-155	hsa-mir-155	21	20427544
hsa-miR-155	hsa-mir-155	21	20133617
hsa-miR-155	hsa-mir-155	21	19956200
hsa-miR-155*	hsa-mir-155	21	20427544
hsa-miR-155*	hsa-mir-155	21	20133617
hsa-miR-155*	hsa-mir-155	21	19956200
hsa-miR-15a	hsa-mir-15a	13	21205967
hsa-miR-15a	hsa-mir-15a	13	19782699
hsa-miR-15a*	hsa-mir-15a	13	21205967
hsa-miR-15a*	hsa-mir-15a	13	19782699
hsa-miR-15b	hsa-mir-15b	3	19782699
hsa-miR-15b*	hsa-mir-15b	3	19782699
hsa-miR-16	hsa-mir-16-1	13	21205967
hsa-miR-16	hsa-mir-16-2	3	21205967
hsa-miR-17	hsa-mir-17	13	20851997
hsa-miR-17	hsa-mir-17	13	20406979
hsa-miR-17	hsa-mir-17	13	20089119
hsa-miR-17	hsa-mir-17	13	19782699
hsa-miR-17	hsa-mir-17	13	19660235
hsa-miR-17	hsa-mir-17	13	18941111
hsa-miR-17	hsa-mir-17	13	18493594
hsa-miR-17	hsa-mir-17	13	20878079
hsa-miR-17	hsa-mir-17	13	18212054
hsa-miR-17	hsa-mir-17	13	20190813
hsa-miR-17*	hsa-mir-17	13	20851997
hsa-miR-17*	hsa-mir-17	13	20406979
hsa-miR-17*	hsa-mir-17	13	20089119
hsa-miR-17*	hsa-mir-17	13	19782699
hsa-miR-17*	hsa-mir-17	13	19660235
hsa-miR-17*	hsa-mir-17	13	18941111
hsa-miR-17*	hsa-mir-17	13	18493594
hsa-miR-17*	hsa-mir-17	13	20878079
hsa-miR-17*	hsa-mir-17	13	18212054
hsa-miR-17*	hsa-mir-17	13	20190813
hsa-miR-181a	hsa-mir-181a-2	9	21274007
hsa-miR-181a	hsa-mir-181a-1	1	21274007
hsa-miR-182	hsa-mir-182	7	19782699
hsa-miR-182	hsa-mir-182	7	20190813
hsa-miR-182*	hsa-mir-182	7	19782699
hsa-miR-182*	hsa-mir-182	7	20190813
hsa-miR-192	hsa-mir-192	11	20647341
hsa-miR-192	hsa-mir-192	11	19088023
hsa-miR-192	hsa-mir-192	11	19074875
hsa-miR-192	hsa-mir-192	11	18798260
hsa-miR-192*	hsa-mir-192	11	20647341
hsa-miR-192*	hsa-mir-192	11	19088023
hsa-miR-192*	hsa-mir-192	11	19074875
hsa-miR-192*	hsa-mir-192	11	18798260
hsa-miR-194	hsa-mir-194-1	1	19074875
hsa-miR-194	hsa-mir-194-2	11	19074875
hsa-miR-195	hsa-mir-195	17	21192064
hsa-miR-195	hsa-mir-195	17	19823043
hsa-miR-195*	hsa-mir-195	17	21192064
hsa-miR-195*	hsa-mir-195	17	19823043
hsa-miR-196a	hsa-mir-196a-1	17	19773200
hsa-miR-196a	hsa-mir-196a-2	12	19773200
hsa-miR-19a	hsa-mir-19a	13	20851997
hsa-miR-19a*	hsa-mir-19a	13	20851997
hsa-miR-19b	hsa-mir-19b-1	13	20851997
hsa-miR-19b	hsa-mir-19b-2	X	20851997
hsa-miR-19b	hsa-mir-19b-1	13	20089119
hsa-miR-19b	hsa-mir-19b-2	X	20089119
hsa-miR-19b-1*	hsa-mir-19b-1	13	20851997
hsa-miR-19b-2*	hsa-mir-19b-2	X	20851997
hsa-miR-203	hsa-mir-203	14	20219920
hsa-miR-204	hsa-mir-204	9	19074875
hsa-miR-208a	hsa-mir-208a	14	20190813
hsa-miR-208b	hsa-mir-208b	14	20190813
hsa-miR-20a	hsa-mir-20a	13	20851997
hsa-miR-20a	hsa-mir-20a	13	20089119
hsa-miR-20a	hsa-mir-20a	13	18941111
hsa-miR-20a	hsa-mir-20a	13	20190813
hsa-miR-20a*	hsa-mir-20a	13	20851997
hsa-miR-20a*	hsa-mir-20a	13	20089119
hsa-miR-20a*	hsa-mir-20a	13	18941111
hsa-miR-20a*	hsa-mir-20a	13	20190813
hsa-miR-20b	hsa-mir-20b	X	18212054
hsa-miR-20b	hsa-mir-20b	X	20190813
hsa-miR-20b*	hsa-mir-20b	X	18212054
hsa-miR-20b*	hsa-mir-20b	X	20190813
hsa-miR-21	hsa-mir-21	17	21078976
hsa-miR-21	hsa-mir-21	17	20447717
hsa-miR-21	hsa-mir-21	17	19730150
hsa-miR-21	hsa-mir-21	17	19082437
hsa-miR-21	hsa-mir-21	17	18798260
hsa-miR-21	hsa-mir-21	17	17991735
hsa-miR-21*	hsa-mir-21	17	21078976
hsa-miR-21*	hsa-mir-21	17	20447717
hsa-miR-21*	hsa-mir-21	17	19730150
hsa-miR-21*	hsa-mir-21	17	19082437
hsa-miR-21*	hsa-mir-21	17	18798260
hsa-miR-21*	hsa-mir-21	17	17991735
hsa-miR-214	hsa-mir-214	1	20534588
hsa-miR-214*	hsa-mir-214	1	20534588
hsa-miR-215	hsa-mir-215	1	20647341
hsa-miR-215	hsa-mir-215	1	19074875
hsa-miR-215	hsa-mir-215	1	18810376
hsa-miR-221	hsa-mir-221	X	19730150
hsa-miR-221	hsa-mir-221	X	19153141
hsa-miR-221*	hsa-mir-221	X	19730150
hsa-miR-221*	hsa-mir-221	X	19153141
hsa-miR-222	hsa-mir-222	X	19956200
hsa-miR-222	hsa-mir-222	X	19153141
hsa-miR-222*	hsa-mir-222	X	19956200
hsa-miR-222*	hsa-mir-222	X	19153141
hsa-miR-23a	hsa-mir-23a	19	20652617
hsa-miR-23a*	hsa-mir-23a	19	20652617
hsa-miR-24	hsa-mir-24-1	9	20041160
hsa-miR-24	hsa-mir-24-2	19	20041160
hsa-miR-24-1*	hsa-mir-24-1	9	20041160
hsa-miR-25	hsa-mir-25	7	20637509
hsa-miR-25	hsa-mir-25	7	19153141
hsa-miR-25	hsa-mir-25	7	18328430
hsa-miR-25	hsa-mir-25	7	19422085
hsa-miR-25*	hsa-mir-25	7	20637509
hsa-miR-25*	hsa-mir-25	7	19153141
hsa-miR-25*	hsa-mir-25	7	18328430
hsa-miR-25*	hsa-mir-25	7	19422085
hsa-miR-26a	hsa-mir-26a-1	3	21199804
hsa-miR-26a	hsa-mir-26a-2	12	21199804
hsa-miR-26a	hsa-mir-26a-1	3	20652617
hsa-miR-26a	hsa-mir-26a-2	12	20652617
hsa-miR-26a-1*	hsa-mir-26a-1	3	21199804
hsa-miR-26a-2*	hsa-mir-26a-2	12	21199804
hsa-miR-26b	hsa-mir-26b	2	21199804
hsa-miR-26b*	hsa-mir-26b	2	21199804
hsa-miR-27a	hsa-mir-27a	19	19950226
hsa-miR-27a*	hsa-mir-27a	19	19950226
hsa-miR-28-5p	hsa-mir-28	3	20190813
hsa-miR-298	hsa-mir-298	20	20190813
hsa-miR-299-5p	hsa-mir-299	14	20190813
hsa-miR-302a	hsa-mir-302a	4	20101223
hsa-miR-302a	hsa-mir-302a	4	21062975
hsa-miR-302a*	hsa-mir-302a	4	20101223
hsa-miR-302a*	hsa-mir-302a	4	21062975
hsa-miR-302b	hsa-mir-302b	4	20101223
hsa-miR-302b	hsa-mir-302b	4	21062975
hsa-miR-302b*	hsa-mir-302b	4	20101223
hsa-miR-302b*	hsa-mir-302b	4	21062975
hsa-miR-302c	hsa-mir-302c	4	20101223
hsa-miR-302c	hsa-mir-302c	4	21062975
hsa-miR-302c*	hsa-mir-302c	4	20101223
hsa-miR-302c*	hsa-mir-302c	4	21062975
hsa-miR-302d	hsa-mir-302d	4	20101223
hsa-miR-302d	hsa-mir-302d	4	21062975
hsa-miR-302d*	hsa-mir-302d	4	20101223
hsa-miR-302d*	hsa-mir-302d	4	21062975
hsa-miR-302f	hsa-mir-302f	0	21062975
hsa-miR-30a	hsa-mir-30a	6	20652617
hsa-miR-30a*	hsa-mir-30a	6	20652617
hsa-miR-32	hsa-mir-32	9	18676839
hsa-miR-32*	hsa-mir-32	9	18676839
hsa-miR-331-3p	hsa-mir-331	12	19229884
hsa-miR-331-5p	hsa-mir-331	12	19229884
hsa-miR-345	hsa-mir-345	14	20190813
hsa-miR-34a	hsa-mir-34a	1	21205967
hsa-miR-34a	hsa-mir-34a	1	20734047
hsa-miR-34a	hsa-mir-34a	1	19701195
hsa-miR-34a	hsa-mir-34a	1	19074875
hsa-miR-34a	hsa-mir-34a	1	18755897
hsa-miR-34a	hsa-mir-34a	1	18677110
hsa-miR-34a	hsa-mir-34a	1	19643983
hsa-miR-34a*	hsa-mir-34a	1	21205967
hsa-miR-34a*	hsa-mir-34a	1	20734047
hsa-miR-34a*	hsa-mir-34a	1	19701195
hsa-miR-34a*	hsa-mir-34a	1	19074875
hsa-miR-34a*	hsa-mir-34a	1	18755897
hsa-miR-34a*	hsa-mir-34a	1	18677110
hsa-miR-34a*	hsa-mir-34a	1	19643983
hsa-miR-34b	hsa-mir-34b	11	21205967
hsa-miR-34b	hsa-mir-34b	11	18755897
hsa-miR-34b*	hsa-mir-34b	11	21205967
hsa-miR-34b*	hsa-mir-34b	11	18755897
hsa-miR-34c-3p	hsa-mir-34c	11	21205967
hsa-miR-34c-3p	hsa-mir-34c	11	18755897
hsa-miR-34c-5p	hsa-mir-34c	11	21205967
hsa-miR-34c-5p	hsa-mir-34c	11	18755897
hsa-miR-363	hsa-mir-363	X	20190813
hsa-miR-363*	hsa-mir-363	X	20190813
hsa-miR-372	hsa-mir-372	19	19823043
hsa-miR-372	hsa-mir-372	19	18212054
hsa-miR-372	hsa-mir-372	19	20190813
hsa-miR-374a	hsa-mir-374a	X	21274007
hsa-miR-374a*	hsa-mir-374a	X	21274007
hsa-miR-377	hsa-mir-377	14	18716028
hsa-miR-377*	hsa-mir-377	14	18716028
hsa-miR-383	hsa-mir-383	8	21368870
hsa-miR-423-3p	hsa-mir-423	17	19950226
hsa-miR-423-3p	hsa-mir-423	17	20190813
hsa-miR-423-5p	hsa-mir-423	17	19950226
hsa-miR-424	hsa-mir-424	X	19956200
hsa-miR-424*	hsa-mir-424	X	19956200
hsa-miR-503	hsa-mir-503	X	19956200
hsa-miR-512-3p	hsa-mir-512-1	19	20101223
hsa-miR-512-3p	hsa-mir-512-2	19	20101223
hsa-miR-515-3p	hsa-mir-515-1	19	20101223
hsa-miR-515-3p	hsa-mir-515-2	19	20101223
hsa-miR-515-3p	hsa-mir-515-1	19	20190813
hsa-miR-515-3p	hsa-mir-515-2	19	20190813
hsa-miR-519a	hsa-mir-519a-1	19	21274007
hsa-miR-519a	hsa-mir-519a-2	19	21274007
hsa-miR-519b-3p	hsa-mir-519b	19	20190813
hsa-miR-519d	hsa-mir-519d	19	20190813
hsa-miR-519e	hsa-mir-519e	19	20190813
hsa-miR-519e*	hsa-mir-519e	19	20190813
hsa-miR-520a-3p	hsa-mir-520a	19	20190813
hsa-miR-520b	hsa-mir-520b	19	20190813
hsa-miR-520h	hsa-mir-520h	19	20190813
hsa-miR-572	hsa-mir-572	4	20190813
hsa-miR-612	hsa-mir-612	11	20417621
hsa-miR-630	hsa-mir-630	15	21274007
hsa-miR-639	hsa-mir-639	19	20190813
hsa-miR-654-3p	hsa-mir-654	14	20190813
hsa-miR-657	hsa-mir-657	17	20190813
hsa-miR-7	hsa-mir-7-1	9	21156648
hsa-miR-7	hsa-mir-7-2	15	21156648
hsa-miR-7	hsa-mir-7-3	19	21156648
hsa-miR-7	hsa-mir-7-1	9	19336466
hsa-miR-7	hsa-mir-7-2	15	19336466
hsa-miR-7	hsa-mir-7-3	19	19336466
hsa-miR-7	hsa-mir-7-1	9	18922890
hsa-miR-7	hsa-mir-7-2	15	18922890
hsa-miR-7	hsa-mir-7-3	19	18922890
hsa-miR-7-1*	hsa-mir-7-1	9	18922890
hsa-miR-9	hsa-mir-9-1	1	19956200
hsa-miR-9	hsa-mir-9-2	5	19956200
hsa-miR-9	hsa-mir-9-3	15	19956200
hsa-miR-92a	hsa-mir-92a-1	13	20851997
hsa-miR-92a	hsa-mir-92a-2	X	20851997
hsa-miR-92a	hsa-mir-92a-1	13	20406979
hsa-miR-92a	hsa-mir-92a-2	X	20406979
hsa-miR-92a	hsa-mir-92a-1	13	19782699
hsa-miR-92a	hsa-mir-92a-2	X	19782699
hsa-miR-92a	hsa-mir-92a-1	13	19660235
hsa-miR-92a	hsa-mir-92a-2	X	19660235
hsa-miR-92a	hsa-mir-92a-1	13	18941111
hsa-miR-92a	hsa-mir-92a-2	X	18941111
hsa-miR-92a	hsa-mir-92a-1	13	19950226
hsa-miR-92a-1*	hsa-mir-92a-1	13	19950226
hsa-miR-93	hsa-mir-93	7	21285944
hsa-miR-93	hsa-mir-93	7	19153141
hsa-miR-93	hsa-mir-93	7	18328430
hsa-miR-93	hsa-mir-93	7	19422085
hsa-miR-93	hsa-mir-93	7	20190813
hsa-miR-93*	hsa-mir-93	7	21285944
hsa-miR-93*	hsa-mir-93	7	19153141
hsa-miR-93*	hsa-mir-93	7	18328430
hsa-miR-93*	hsa-mir-93	7	19422085
hsa-miR-93*	hsa-mir-93	7	20190813
hsa-miR-942	hsa-mir-942	1	20190813
hsa-miR-96	hsa-mir-96	7	21203424
hsa-miR-96	hsa-mir-96	7	19422085
hsa-miR-96*	hsa-mir-96	7	21203424
hsa-miR-96*	hsa-mir-96	7	19422085

ID in Tarbase	Data Type	Support Type	miRNA	Gene	Direct Support	Publication
231	mRNA cleavage	TRUE	miR-106a	CDKN1A / p21	Luciferase assay / antisense	18212054
232	mRNA cleavage	TRUE	miR-106b	CDKN1A / p21	Luciferase assay - scrambled miRNA	18212054
494	mRNA cleavage	TRUE	miR-17-5p	CDKN1A / p21	Luciferase assay - mutant MRE	18212054
531	mRNA cleavage	TRUE	miR-20b	CDKN1A / p21	Luciferase assay	18212054
620	mRNA cleavage	TRUE	miR-372	CDKN1A / p21	Luciferase assay - mutant MRE	18212054
Ensembl	Protein Type	Differentially expressed in	Pathology or Event	Mis Regulation	Gene Expression	Tumour Involvement
ENSG00000124762		n_a	breast cancer	up regulated	"lymphocyte, macrophage, muscle cell"	"benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"
ENSG00000124762		n_a	Non-small-cell lung cancer (NSCLC)	down regulated	"lymphocyte, macrophage, muscle cell"	"benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"
ENSG00000124762		mesenchymal-epithelial transition (MET)	primary ovarian cancer	down regulated	"lymphocyte, macrophage, muscle cell"	"benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"
ENSG00000124762		mesenchymal-epithelial transition (MET)	metastasis	down regulated	"lymphocyte, macrophage, muscle cell"	"benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"
ENSG00000124762		myocytes / breast	ER-alpha negative breast cancer	up regulated	"lymphocyte, macrophage, muscle cell"	"benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"

Cis-Nats regulation

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Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

AutismKB 2.0

Annotation Detail for CDKN1A

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics