AutismKB 2.0

Annotation Detail for NET1


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Basic Information Top
Gene Symbol:NET1 ( ARHGEF8,NET1A )
Gene Full Name: neuroepithelial cell transforming 1
Band: 10p15.1
Quick LinksEntrez ID:10276; OMIM: 606450; Uniprot ID:ARHG8_HUMAN; ENSEMBL ID: ENSG00000173848; HGNC ID: 14592
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
19Nuclear localization signal (By
21Phosphoserine.
32Phosphoserine.
72Nuclear localization signal (By
100Phosphoserine.
106Phosphoserine.
508Phosphoserine (By similarity).
Location(AA) Modifications Resource
Location(AA) Modification Resource
1AcetylmethionineHMM predict
17Phosphoserine(PKC)HMM predict
21Phosphoserine(PKG)HMM predict
21Phosphoserine(PKC)HMM predict
21Phosphoserine(PKA)HMM predict
21Phosphoserine(IKK)HMM predict
32O-linkedHMM predict
36Phosphoserine(IKK)HMM predict
36O-linkedHMM predict
50Phosphoserine(PKA)HMM predict
106Phosphoserine(CDC2)HMM predict
139O-linkedHMM predict
142PhosphoserineHMM predict
142O-linkedHMM predict
146Phosphothreonine(CDK)HMM predict
153Phosphoserine(PKG)HMM predict
167Phosphoserine(PKG)HMM predict
169Phosphothreonine(PKC)HMM predict
200Phosphotyrosine(Syk)HMM predict
211Phosphoserine(CK1)HMM predict
296Phosphoserine(CDC2)HMM predict
329Phosphothreonine(CDC2)HMM predict
351Phosphoserine(CK2)HMM predict
453MethylarginineHMM predict
474O-linkedHMM predict
508Phosphoserine(CDC2)HMM predict
539O-linkedHMM predict
539Phosphoserine(PKB)HMM predict
539O-linkedHMM predict
539Phosphoserine(PKA)HMM predict
539Phosphoserine(PKG)HMM predict
540Phosphothreonine(PKC)HMM predict
554Phosphotyrosine(INSR)HMM predict
568Phosphoserine(CK1)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001047160
  • Location:chr10 5444517-5490423
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
E2F4 G0GSE7516 5444183 5444703 520 75
Fos K562GSE19551 5444030 5444731 701 137
LIN9 G0GSE7516 5444148 5444765 617 61
LIN9 SGSE7516 5444293 5444734 441 4
Rb SenescentGSE19898 5444366 5444587 221 41
p130 QuiescentGSE19898 5444293 5444622 329 60
p130 shRbQuiescentGSE19898 5443990 5444677 687 184
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 5466035 5466356 321 0
CTCF CD4GSE12889 5474035 5474354 319 0
CTCF CD4SISSRdata 5466035 5466356 321 0
CTCF CD4SISSRdata 5474035 5474354 319 0
KLF4 hESGSE17917 5444778 5445057 279 0
Oct1 HelaGSE14283 5460424 5460468 44 0
Oct1 HelaGSE14283 5473231 5473269 38 0
PHF8 293TGSE20725 5444193 5445137 944 0
PHF8 HeLaGSE20725 5478188 5478846 658 0
RARG MCF7GSE15244 5457171 5457370 199 0
USF1 HepG2E 5475701 5480926 5225 0
hScc1 BcellGSE12603 5466090 5466531 441 0
hScc1 CdLSGSE12603 5474012 5474492 480 0
p130 SenescentGSE19898 5444316 5444915 599 0
p130 shRbSenescentGSE19898 5444207 5444937 730 0
Validated miRNA targets Top
Cis-Nats regulation Top

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018