AutismKB 2.0

Annotation Detail for LANCL1


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Basic Information Top
Gene Symbol:LANCL1 ( GPR69A,p40 )
Gene Full Name: LanC lantibiotic synthetase component C-like 1 (bacterial)
Band: 2q34
Quick LinksEntrez ID:10314; OMIM: 604155; Uniprot ID:LANC1_HUMAN; ENSEMBL ID: ENSG00000115365; HGNC ID: 6508
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
142N6-acetyllysine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
29Phosphothreonine(MAPK)HMM predict
33Phosphoserine(ATM)HMM predict
62Phosphotyrosine(INSR)HMM predict
198N-linkedHMM predict
214Phosphotyrosine(Syk)HMM predict
298Phosphotyrosine(Jak)HMM predict
368Phosphothreonine(MAPK)HMM predict
395ProlineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006055
  • Location:chr2 211004220-211049675
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Fos K562GSE19551 211049615 211049908 293 86
P300 T0-glioblastomaGSE21026 211049323 211051181 1858 577
Rb QuiescentGSE19898 211049555 211049848 293 26
p130 shRbSenescentGSE19898 211049465 211049932 467 23
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 211018168 211018450 282 0
CTCF CD4SISSRdata 211018168 211018450 282 0
CTCF G2GSE9613 211049402 211049787 385 0
PHF8 293TGSE20725 211049165 211050082 917 0
Rb SenescentGSE19898 211049463 211049812 349 0
hScc1 BcellGSE12603 211049402 211049787 385 0
p130 QuiescentGSE19898 211049433 211049890 457 0
p130 shRbQuiescentGSE19898 211049349 211049735 386 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
15589 EST chr2 211118340 211151112 29631 mRNA LANCL1 chr2 211121481 211166937 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018