AutismKB 2.0

Annotation Detail for IKZF1


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Basic Information Top
Gene Symbol:IKZF1 ( Hs.54452,IK1,IKAROS,LYF1,PRO0758,ZNFN1A1,hIk-1 )
Gene Full Name: IKAROS family zinc finger 1 (Ikaros)
Band: 7p12.2
Quick LinksEntrez ID:10320; OMIM: 603023; Uniprot ID:IKZF1_HUMAN; ENSEMBL ID: ENSG00000185811; HGNC ID: 13176
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
13Phosphoserine (By similarity).
23Phosphothreonine (By similarity).
63Phosphoserine.
101Phosphoserine (By similarity).
140Phosphothreonine (By similarity).
168Phosphoserine (By similarity).
196Phosphoserine (By similarity).
295Phosphoserine (By similarity).
361Phosphoserine.
364Phosphoserine.
377Phosphoserine.
389Phosphoserine (By similarity).
391Phosphoserine (By similarity).
393Phosphoserine (By similarity).
397Phosphoserine (By similarity).
398Phosphothreonine (By similarity).
442Phosphoserine.
Location(AA) Modifications Resource
No data
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006060
  • Location:chr7 50314923-50438052
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 50296113 50296265 152 18735
CTCF G2GSE9613 50312719 50313056 337 2036
CTCF G2GSE9613 50313765 50313949 184 1067
H3K27me3 colorectalcancer 50312373 50312920 547 2277
NFkBII GM12878GSE19485 50301660 50304935 3275 11626
NFkBII GM12892GSE19485 50302116 50303405 1289 12163
TAF HelaGSE8489 50312373 50312551 178 2462
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 50453214 50453599 385 15354
CTCF CD4SISSRdata 50453214 50453599 385 15354
CTCF G2GSE9613 50439557 50439774 217 1613
CTCF G2GSE9613 50444914 50445165 251 6987
CTCF G2GSE9613 50448045 50448217 172 10079
CTCF G2GSE9613 50453361 50453942 581 15599
Oct1 HelaGSE14283 50455271 50455308 37 17237
hScc1 BcellGSE12603 50441667 50442059 392 3811
hScc1 BcellGSE12603 50452959 50453942 983 15398
hScc1 CdLSGSE12603 50453267 50453862 595 15512
hScc1 G2GSE9613 50453361 50453942 581 15599
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 50394586 50396564 1978 0
CTCF CD4GSE12889 50404595 50404994 399 0
CTCF CD4SISSRdata 50404595 50404994 399 0
CTCF G2GSE9613 50337559 50338097 538 0
CTCF G2GSE9613 50388549 50388730 181 0
CTCF G2GSE9613 50390368 50390893 525 0
CTCF G2GSE9613 50392009 50392500 491 0
CTCF G2GSE9613 50397998 50398863 865 0
CTCF G2GSE9613 50404527 50404929 402 0
CTCF G2GSE9613 50428670 50429003 333 0
CTCF G2GSE9613 50435022 50435925 903 0
KLF4 hESGSE17917 50410885 50411052 167 0
NFkBII GM12878GSE19485 50385190 50388417 3227 0
NFkBII GM12892GSE19485 50337146 50338266 1120 0
NRSF mAbJurkat 50314929 50316790 1861 0
NRSF mAbJurkat 50396516 50396755 239 0
TFAP2C MCF7GSE21234 50381691 50382137 446 0
hScc1 BcellGSE12603 50314306 50315656 1350 0
hScc1 BcellGSE12603 50317455 50317746 291 0
hScc1 BcellGSE12603 50318958 50319172 214 0
hScc1 BcellGSE12603 50404489 50404968 479 0
hScc1 BcellGSE12603 50435046 50435558 512 0
hScc1 CdLSGSE12603 50404315 50405196 881 0
p63 keratinocytesGSE17611 50414020 50414992 972 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-1 hsa-mir-1-2 18 19959133
hsa-miR-1 hsa-mir-1-1 20 19959133
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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