AutismKB 2.0

Annotation Detail for TUBB3


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Basic Information Top
Gene Symbol:TUBB3 ( CFEOM3A,TUBB4,beta-4 )
Gene Full Name: tubulin, beta 3
Band: 16q24.3
Quick LinksEntrez ID:10381; OMIM: 602661; Uniprot ID:TBB3_HUMAN; ENSEMBL ID: ENSG00000198211; HGNC ID: 20772
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
58N6-acetyllysine.
Location(AA) Modifications Resource
409Phosphothreonine (GRK-2)Phospho.ELM 6.0
420Phosphoserine (GRK-2)Phospho.ELM 6.0
437PhosphotyrosinePhospho.ELM 6.0
444Phosphoserine (GRK-2;MAPK
Location(AA) Modification Resource
59Phosphotyrosine(INSR)HMM predict
172Phosphoserine(CDC2)HMM predict
176O-linkedHMM predict
184N-linkedHMM predict
222Phosphotyrosine(SRC)HMM predict
234Phosphoserine(IKK)HMM predict
281Phosphotyrosine(EGFR)HMM predict
285Phosphothreonine(PKC)HMM predict
312Phosphothreonine(PKC)HMM predict
322Phosphoserine(PKG)HMM predict
337N-linkedHMM predict
370N-linkedHMM predict
409Phosphothreonine(CK2)HMM predict
425Phosphotyrosine(SRC)HMM predict
425Phosphotyrosine(Syk)HMM predict
429PhosphothreonineHMM predict
437Phosphotyrosine(EGFR)HMM predict
444Phosphoserine(CK1)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006086
  • Location:chr16 88517245-88530005
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
PHF8 Hs68minusFBSGSE20725 88516172 88517676 1504 322
Rb QuiescentGSE19898 88516545 88516877 332 535
Rb SenescentGSE19898 88516395 88516856 461 620
Rb shRbSenescenceGSE19898 88516439 88516729 290 662
p130 QuiescentGSE19898 88516204 88516619 415 834
p130 QuiescentGSE19898 88516641 88516749 108 551
p130 SenescentGSE19898 88515699 88517057 1358 868
p130 shRbQuiescentGSE19898 88515815 88516728 913 974
p130 shRbSenescentGSE19898 88516189 88516956 767 673
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER E2-MCF7GSE14664 88530706 88530751 45 723
ER Fulvestrant-MCF7GSE14664 88530705 88530740 35 717
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
NRSF JurkatGSE13047 88516425 88518881 2456 0
NRSF JurkatGSE13047 88518886 88520704 1818 0
NRSF mAbJurkat 88518817 88519119 302 0
NRSF mAbJurkat 88521363 88521938 575 0
NRSF mAbJurkat 88523223 88523582 359 0
NRSF-mono JurkatQuESTdata 88516452 88518859 2407 0
NRSF-mono JurkatQuESTdata 88519353 88520667 1314 0
NRSF pAbJurkat 88521363 88521938 575 0
NRSF-poly JurkatQuESTdata 88516850 88519163 2313 0
NRSF-poly JurkatQuESTdata 88519207 88520726 1519 0
Rb QuiescentGSE19898 88520068 88520536 468 0
Rb SenescentGSE19898 88520379 88520511 132 0
TFAP2C MCF7GSE21234 88518760 88519169 409 0
hScc1 BcellGSE12603 88520233 88520450 217 0
hScc1 BcellGSE12603 88528864 88529443 579 0
p130 shRbSenescentGSE19898 88518344 88518605 261 0
p130 shRbSenescentGSE19898 88520205 88520461 256 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-200c hsa-mir-200c 12 19435871
hsa-miR-200c hsa-mir-200c 12 19435871
hsa-miR-200c hsa-mir-200c 12 19435871
hsa-miR-200c* hsa-mir-200c 12 19435871
hsa-miR-200c* hsa-mir-200c 12 19435871
hsa-miR-200c* hsa-mir-200c 12 19435871
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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