AutismKB 2.0

Annotation Detail for CDR2


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Basic Information Top
Gene Symbol:CDR2 ( CDR62,Yo )
Gene Full Name: cerebellar degeneration-related protein 2, 62kDa
Band: 16p12.2
Quick LinksEntrez ID:1039; OMIM: 117340; Uniprot ID:CDR2_HUMAN; ENSEMBL ID: ENSG00000140743; HGNC ID: 1799
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
48Phosphoserine(ATM)HMM predict
114Phosphoserine(CK1)HMM predict
145Phosphoserine(CDC2)HMM predict
218Phosphothreonine(PKA)HMM predict
218Phosphothreonine(PKC)HMM predict
231Phosphoserine(CK2)HMM predict
231Phosphoserine(CK1)HMM predict
310Phosphoserine(CK1)HMM predict
310Phosphoserine(CK2)HMM predict
311Phosphoserine(CK1)HMM predict
373Phosphoserine(CK1)HMM predict
381Phosphothreonine(PKC)HMM predict
414O-linkedHMM predict
414O-linkedHMM predict
414Phosphoserine(IKK)HMM predict
415Phosphoserine(CDC2)HMM predict
415O-linkedHMM predict
417O-linkedHMM predict
418Phosphothreonine(MAPK)HMM predict
418Phosphothreonine(CDC2)HMM predict
418PhosphothreonineHMM predict
437LysineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001802
  • Location:chr16 22264759-22293438
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 22305561 22306373 812 12529
ER E2-MCF7GSE14664 22305034 22305117 83 11637
ER Fulvestrant-MCF7GSE14664 22304985 22305057 72 11583
Fos K562GSE19551 22293139 22293870 731 66
P300 T0-glioblastomaGSE21026 22305689 22306379 690 12596
P300 T30-glioblastomaGSE21026 22305648 22306409 761 12590
Rb GrowingGSE19898 22293425 22293706 281 127
Rb QuiescentGSE19898 22293782 22294023 241 464
Rb SenescentGSE19898 22293539 22294045 506 354
p130 QuiescentGSE19898 22293382 22293638 256 72
p130 SenescentGSE19898 22293295 22293666 371 42
p130 SenescentGSE19898 22293698 22293882 184 352
p130 SenescentGSE19898 22293946 22294220 274 645
p130 shRbQuiescentGSE19898 22293401 22293949 548 237
p130 shRbSenescentGSE19898 22293311 22293860 549 147
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 22293048 22293423 375 0
FOXA1 MCF7GSE15244 22287335 22287840 505 0
Fos K562GSE19551 22272385 22272874 489 0
H3ac HepG2E 22290056 22290645 589 0
H3ac HepG2E 22291008 22292824 1816 0
NRSF mAbJurkat 22287335 22288463 1128 0
NRSF-mono JurkatQuESTdata 22288131 22288490 359 0
NRSF-poly JurkatQuESTdata 22288028 22288436 408 0
Oct1 H2O2-HelaGSE14283 22269408 22269441 33 0
PHF8 Hs68minusFBSGSE20725 22292533 22293925 1392 0
RARA MCF7GSE15244 22287335 22288244 909 0
RARA MCF7GSE15244 22291008 22291834 826 0
hScc1 BcellGSE12603 22292706 22293487 781 0
hScc1 CdLSGSE12603 22292559 22293618 1059 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018