AutismKB 2.0

Annotation Detail for NDRG1


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Basic Information Top
Gene Symbol:NDRG1 ( CAP43,CMT4D,DRG1,GC4,HMSNL,NDR1,NMSL,PROXY1,RIT42,RTP,TARG1,TDD5 )
Gene Full Name: N-myc downstream regulated 1
Band: 8q24.22
Quick LinksEntrez ID:10397; OMIM: 605262; Uniprot ID:NDRG1_HUMAN; ENSEMBL ID: ENSG00000104419; HGNC ID: 7679
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2Phosphoserine (By similarity).
319Phosphoserine.
326Phosphoserine.
328Phosphothreonine.
330Phosphoserine.
332Phosphoserine.
333Phosphoserine.
335Phosphothreonine.
336Phosphoserine.
346Phosphothreonine (By similarity).
362Phosphoserine (By similarity).
364Phosphoserine.
366Phosphothreonine.
375Phosphothreonine.
Location(AA) Modifications Resource
319Phosphoserine.Swiss-Prot 53.0
319PhosphoserinePhospho.ELM 6.0
326Phosphoserine.Swiss-Prot 53.0
328Phosphothreonine.Swiss-Prot 53.0
328PhosphothreoninePhospho.ELM 6.0
330Phosphoserine.Swiss-Prot 53.0
330PhosphoserinePhospho.ELM 6.0
335Phosphothreonine (By similarity).Swiss-Prot 53.0
336PhosphoserinePhospho.ELM 6.0
336Phosphoserine.Swiss-Prot 53.0
342PhosphoserinePhospho.ELM 6.0
346PhosphothreoninePhospho.ELM 6.0
352PhosphoserinePhospho.ELM 6.0
356PhosphothreoninePhospho.ELM 6.0
362PhosphoserinePhospho.ELM 6.0
366PhosphothreoninePhospho.ELM 6.0
Location(AA) Modification Resource
110Phosphotyrosine(Abl)HMM predict
296Phosphoserine(ATM)HMM predict
314Phosphotyrosine(INSR)HMM predict
330O-linkedHMM predict
330Phosphoserine(CAMK2)HMM predict
330Phosphoserine(IKK)HMM predict
330Phosphoserine(PKB)HMM predict
336Phosphoserine(CK1)HMM predict
394S-farnesylHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006096
  • Location:chr8 134318595-134378679
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 134378274 134379424 1150 170
p130 shRbQuiescentGSE19898 134378911 134379453 542 503
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 134315851 134316498 647 2421
FoxA1 MCF7MACSdata 134316081 134316429 348 2341
RARG MCF7GSE15244 134315924 134316498 574 2385
TFAP2C MCF7GSE21234 134315931 134316506 575 2377
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER MCF7GSE19013 134360428 134360820 392 0
ER MCF7GSE19013 134374111 134374649 538 0
FOXA1 DLD1GSE12801 134330713 134331607 894 0
FOXA1 MCF7GSE15244 134324298 134324668 370 0
FOXA1 MCF7GSE15244 134327728 134328167 439 0
FOXA1 MCF7GSE15244 134330782 134331715 933 0
FOXA1 MCF7GSE15244 134341259 134341620 361 0
FOXA1 MCF7GSE15244 134374561 134375411 850 0
FOXA1 MCF7GSE15244 134375792 134376029 237 0
FOXA1 MCF7GSE15244 134377945 134378626 681 0
Fos K562GSE19551 134375590 134376090 500 0
FoxA1 MCF7MACSdata 134331524 134331694 170 0
FoxA1 MCF7MACSdata 134374868 134375148 280 0
GATA3 MCF7GSE15244 134321679 134322201 522 0
GATA3 MCF7GSE15244 134330713 134332142 1429 0
H3K4me2 HCT116GSE10453 134376223 134377004 781 0
H3ac HepG2E 134377987 134378315 328 0
NRSF pAbJurkat 134348434 134349106 672 0
PHF8 HeLaGSE20725 134377488 134379816 2328 0
RARA MCF7GSE15244 134318719 134319323 604 0
RARA MCF7GSE15244 134324298 134324483 185 0
RARA MCF7GSE15244 134330782 134331680 898 0
RARA MCF7GSE15244 134354563 134354740 177 0
RARA MCF7GSE15244 134355272 134356152 880 0
RARA MCF7GSE15244 134374706 134375411 705 0
RARG MCF7GSE15244 134318673 134319484 811 0
RARG MCF7GSE15244 134321679 134322317 638 0
RARG MCF7GSE15244 134324298 134324446 148 0
RARG MCF7GSE15244 134330758 134331860 1102 0
RARG MCF7GSE15244 134354563 134354740 177 0
RARG MCF7GSE15244 134355177 134355792 615 0
RARG MCF7GSE15244 134373514 134373843 329 0
RARG MCF7GSE15244 134374450 134375411 961 0
RARG MCF7GSE15244 134375792 134376029 237 0
Rb shRbSenescenceGSE19898 134363181 134363344 163 0
TFAP2C MCF7GSE21234 134330859 134331779 920 0
TFAP2C MCF7GSE21234 134355171 134355891 720 0
hScc1 BcellGSE12603 134338273 134338508 235 0
hScc1 BcellGSE12603 134377354 134379775 2421 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-34a hsa-mir-34a 1 20606648
hsa-miR-34a hsa-mir-34a 1 20606648
hsa-miR-34a* hsa-mir-34a 1 20606648
hsa-miR-34a* hsa-mir-34a 1 20606648
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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