AutismKB 2.0

Annotation Detail for NDC80


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Basic Information Top
Gene Symbol:NDC80 ( HEC,HEC1,KNTC2,TID3,hsNDC80 )
Gene Full Name: NDC80 homolog, kinetochore complex component (S. cerevisiae)
Band: 18p11.32
Quick LinksEntrez ID:10403; OMIM: 607272; Uniprot ID:NDC80_HUMAN; ENSEMBL ID: ENSG00000080986; HGNC ID: 16909
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
31Phosphothreonine.
34Phosphothreonine.
44Phosphoserine.
55Phosphoserine.
62Phosphoserine.
69Phosphoserine.
76Phosphoserine.
77Phosphoserine.
165Phosphoserine; by NEK2.
Location(AA) Modifications Resource
No data
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006101
  • Location:chr18 2561604-2606625
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
E2F4 G0GSE7516 2560886 2562212 1326 56
PHF8 HeLaGSE20725 2560963 2562173 1210 37
p130 shRbSenescentGSE19898 2561012 2562116 1104 41
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Fos K562GSE19551 2617862 2618347 485 11479
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K4me3 colorectalcancer 2561348 2562522 1174 0
H3ac HepG2E 2560850 2563588 2738 0
LIN9 G0GSE7516 2560850 2562416 1566 0
LIN9 SGSE7516 2561020 2562658 1638 0
TAF HelaGSE8489 2561730 2562658 928 0
p130 G0GSE7516 2560886 2562380 1494 0
p130 SGSE7516 2561133 2562882 1749 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018