AutismKB 2.0

Annotation Detail for VAV3


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Basic Information Top
Gene Symbol:VAV3 ( FLJ40431 )
Gene Full Name: vav 3 guanine nucleotide exchange factor
Band: 1p13.3
Quick LinksEntrez ID:10451; OMIM: 605541; Uniprot ID:VAV3_HUMAN; ENSEMBL ID: ENSG00000134215; HGNC ID: 12659
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
141Phosphotyrosine.
786Phosphoserine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
36Phosphothreonine(PKC)HMM predict
71S-palmitoylHMM predict
141Phosphotyrosine(Syk)HMM predict
160Phosphotyrosine(INSR)HMM predict
160Phosphotyrosine(EGFR)HMM predict
160Phosphotyrosine(SRC)HMM predict
164Phosphotyrosine(Syk)HMM predict
173Phosphotyrosine(Syk)HMM predict
283Phosphoserine(ATM)HMM predict
290Phosphoserine(CK1)HMM predict
294Phosphotyrosine(Jak)HMM predict
294Phosphotyrosine(INSR)HMM predict
319Phosphothreonine(PKC)HMM predict
375N-linkedHMM predict
455N-linkedHMM predict
547S-palmitoylHMM predict
602N-linkedHMM predict
604O-linkedHMM predict
606O-linkedHMM predict
691N-linkedHMM predict
766Phosphotyrosine(Syk)HMM predict
786Phosphoserine(MAPK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006113
  • Location:chr1 107915312-108309060
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 108308928 108309317 389 62
ER Fulvestrant-MCF7GSE14664 108313896 108313931 35 4853
Oct1 HelaGSE14283 108313895 108313930 35 4852
PAX3-FKHR Rh4GSE19063 108318937 108322171 3234 11494
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Myc K562GSE19551 107914541 107915229 688 428
Nanog ESGSE20650 107914502 107914713 211 705
Nanog ESGSE20650 107914868 107915281 413 238
Oct1 HelaGSE14283 107898817 107898854 37 16477
Oct4 ESGSE20650 107914600 107914703 103 661
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 108188147 108189838 1691 0
CBP JurkatGSE17954 108208301 108210733 2432 0
CTCF CD4GSE12889 108047478 108047726 248 0
CTCF CD4GSE12889 108126423 108126783 360 0
CTCF CD4SISSRdata 108047478 108047726 248 0
CTCF CD4SISSRdata 108126423 108126783 360 0
CTCF G2GSE9613 108094395 108094873 478 0
ER MCF7GSE19013 108100469 108101015 546 0
FOXA1 MCF7GSE15244 107916264 107917561 1297 0
FOXA1 MCF7GSE15244 107985174 107986119 945 0
FOXA1 MCF7GSE15244 108027169 108027713 544 0
FOXA1 MCF7GSE15244 108071949 108072535 586 0
FOXA1 MCF7GSE15244 108082629 108084124 1495 0
FOXA1 MCF7GSE15244 108111341 108111907 566 0
Fos K562GSE19551 108280637 108280858 221 0
FoxA1 MCF7MACSdata 107985538 107985867 329 0
FoxA1 MCF7MACSdata 108027314 108027480 166 0
FoxA1 MCF7MACSdata 108072110 108072400 290 0
H3K27me3 colorectalcancer 108308340 108309037 697 0
NFkBII GM12878GSE19485 108120585 108122592 2007 0
NRSF mAbJurkat 108283818 108284697 879 0
NRSF-mono JurkatQuESTdata 108283428 108283839 411 0
NRSF-poly JurkatQuESTdata 108283443 108283876 433 0
Nanog ESGSE20650 108148885 108149359 474 0
Oct1 H2O2-HelaGSE14283 107931908 107931935 27 0
Oct1 H2O2-HelaGSE14283 107973765 107973801 36 0
Oct1 H2O2-HelaGSE14283 108129952 108129984 32 0
Oct1 HelaGSE14283 107931868 107931934 66 0
Oct1 HelaGSE14283 107960833 107960875 42 0
Oct1 HelaGSE14283 107965229 107965265 36 0
Oct1 HelaGSE14283 107973752 107973813 61 0
Oct1 HelaGSE14283 107975186 107975218 32 0
Oct1 HelaGSE14283 107981535 107981571 36 0
Oct1 HelaGSE14283 108056374 108056425 51 0
Oct1 HelaGSE14283 108183617 108183651 34 0
Oct1 HelaGSE14283 108306143 108306223 80 0
Oct4 hESGSE17917 108148999 108149205 206 0
P300 T30-glioblastomaGSE21026 108094543 108095067 524 0
P300 T30-glioblastomaGSE21026 108221135 108221776 641 0
P300 T30-glioblastomaGSE21026 108280330 108281656 1326 0
RARA MCF7GSE15244 107916264 107917695 1431 0
RARA MCF7GSE15244 107937836 107938825 989 0
RARA MCF7GSE15244 107941332 107941975 643 0
RARA MCF7GSE15244 107970351 107971209 858 0
RARA MCF7GSE15244 107985211 107985886 675 0
RARA MCF7GSE15244 107987377 107988540 1163 0
RARA MCF7GSE15244 108027128 108027883 755 0
RARA MCF7GSE15244 108032649 108034640 1991 0
RARA MCF7GSE15244 108035146 108036179 1033 0
RARA MCF7GSE15244 108082629 108084092 1463 0
RARA MCF7GSE15244 108224362 108224616 254 0
RARA MCF7GSE15244 108280677 108281541 864 0
RARA MCF7GSE15244 108283818 108284697 879 0
RARG MCF7GSE15244 107916200 107917619 1419 0
RARG MCF7GSE15244 108280825 108281541 716 0
Sox2 hESGSE18292 108126353 108126761 408 0
Stat6 IL-4-hr1GSE17850 108241334 108242136 802 0
TFAP2C MCF7GSE21234 107987824 107988364 540 0
TFAP2C MCF7GSE21234 108026425 108027018 593 0
TFAP2C MCF7GSE21234 108027036 108027829 793 0
TFAP2C MCF7GSE21234 108032489 108032939 450 0
TFAP2C MCF7GSE21234 108033216 108034289 1073 0
TFAP2C MCF7GSE21234 108035546 108036238 692 0
TFAP2C MCF7GSE21234 108174562 108175060 498 0
TFAP2C MCF7GSE21234 108280580 108281359 779 0
VDR GM10855-stimGSE22484 108050018 108052084 2066 0
hScc1 BcellGSE12603 108056144 108056304 160 0
hScc1 BcellGSE12603 108094536 108094896 360 0
hScc1 BcellGSE12603 108308219 108309480 1261 0
hScc1 CdLSGSE12603 108094395 108094973 578 0
hScc1 CdLSGSE12603 108126346 108126970 624 0
hScc1 G2GSE9613 108094395 108094873 478 0
p63 keratinocytesGSE17611 108021557 108022464 907 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
1217 EST chr1 108219106 108249111 474 mRNA VAV3 chr1 107825831 108219580 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018