AutismKB 2.0

Annotation Detail for TAB1


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Basic Information Top
Gene Symbol:TAB1 ( 3'-Tab1,MAP3K7IP1,MGC57664 )
Gene Full Name: TGF-beta activated kinase 1/MAP3K7 binding protein 1
Band: 22q13.1
Quick LinksEntrez ID:10454; OMIM: 602615; Uniprot ID:TAB1_HUMAN; ENSEMBL ID: ENSG00000100324; HGNC ID: 18157
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
7Phosphoserine.
378Phosphoserine.
438Phosphoserine.
Location(AA) Modifications Resource
423Phosphoserine (MAPK14)Phospho.ELM 6.0
431Phosphothreonine (MAPK14)Phospho.ELM 6.0
438Phosphoserine (MAPK14)Phospho.ELM 6.0
Location(AA) Modification Resource
7Phosphoserine(IKK)HMM predict
16Phosphoserine(IKK)HMM predict
34N-linkedHMM predict
44Phosphothreonine(PKC)HMM predict
133Phosphoserine(ATM)HMM predict
157Phosphothreonine(PKC)HMM predict
252Phosphotyrosine(Jak)HMM predict
293Phosphotyrosine(SRC)HMM predict
373Phosphoserine(ATM)HMM predict
376O-linkedHMM predict
378Phosphoserine(CDC2)HMM predict
378O-linkedHMM predict
378PhosphoserineHMM predict
395O-linkedHMM predict
395Phosphoserine(IKK)HMM predict
395O-linkedHMM predict
400O-linkedHMM predict
401Phosphoserine(CK1)HMM predict
401Phosphoserine(IKK)HMM predict
401O-linkedHMM predict
403O-linkedHMM predict
404Phosphoserine(IKK)HMM predict
413Phosphoserine(ATM)HMM predict
426Phosphothreonine(PKC)HMM predict
436N-linkedHMM predict
446O-linkedHMM predict
450O-linkedHMM predict
452O-linkedHMM predict
453O-linkedHMM predict
453O-linkedHMM predict
455Phosphoserine(CK1)HMM predict
456Phosphoserine(CK1)HMM predict
457Phosphoserine(CK1)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006116
  • Location:chr22 38125704-38157830
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 38125503 38125786 283 60
CTCF CD4SISSRdata 38125503 38125786 283 60
CTCF JurkatGSE12889 38125481 38125804 323 62
TAFII hESGSE17917 38125451 38125944 493 7
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 38125588 38126099 511 0
ETS1 JurkatGSE17954 38125095 38126429 1334 0
NFkBII GM12892GSE19485 38125164 38126499 1335 0
NFkBII GM15510GSE19485 38125071 38126526 1455 0
NRSF JurkatSISSRdata 38125638 38125938 300 0
P300 T30-glioblastomaGSE21026 38125310 38126534 1224 0
PHF8 293TGSE20725 38125278 38126390 1112 0
PHF8 HeLaGSE20725 38125140 38126452 1312 0
Rb shRbQuiescentGSE19898 38147994 38148210 216 0
TAF k562GSE8489 38127029 38127402 373 0
hScc1 BcellGSE12603 38125588 38126099 511 0
hScc1 BcellGSE12603 38152722 38152935 213 0
hScc1 BcellGSE12603 38155797 38156731 934 0
hScc1 CdLSGSE12603 38125588 38125873 285 0
p63 keratinocytesGSE17611 38134097 38134824 727 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018