AutismKB 2.0

Annotation Detail for UBE2E3


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Basic Information Top
Gene Symbol:UBE2E3 ( UBCH9,UbcM2 )
Gene Full Name: ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
Band: 2q31.3
Quick LinksEntrez ID:10477; OMIM: 604151; Uniprot ID:UB2E3_HUMAN; ENSEMBL ID: ENSG00000170035; HGNC ID: 12479
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
3Phosphoserine.
12Phosphoserine.
91Phosphotyrosine (By similarity).
Location(AA) Modifications Resource
12Phosphoserine.Swiss-Prot 53.0
12PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
8Phosphoserine(CK2)HMM predict
12Phosphoserine(IKK)HMM predict
12Phosphoserine(ATM)HMM predict
14O-linkedHMM predict
14Phosphoserine(CK1)HMM predict
16O-linkedHMM predict
17Phosphoserine(CK2)HMM predict
17Phosphoserine(IKK)HMM predict
19Phosphoserine(CK2)HMM predict
20Phosphoserine(CK2)HMM predict
41Phosphoserine(PKG)HMM predict
41Phosphoserine(IKK)HMM predict
56O-linkedHMM predict
60Phosphoserine(PKG)HMM predict
61Phosphothreonine(PKC)HMM predict
91Phosphotyrosine(Syk)HMM predict
152N-linkedHMM predict
154Phosphoserine(IKK)HMM predict
158Phosphothreonine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006357
  • Location:chr2 181553586-181636394
  • strand:+
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 181650077 181650441 364 13865
CTCF CD4SISSRdata 181650077 181650441 364 13865
Oct1 HelaGSE14283 181651146 181651185 39 14771
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 181631601 181632027 426 0
CTCF CD4SISSRdata 181631601 181632027 426 0
CTCF HelaGSE12889 181553689 181553871 182 0
CTCF G2GSE9613 181553124 181554199 1075 0
H3K4me3 colorectalcancer 181554474 181554847 373 0
H3ac HepG2E 181554314 181554769 455 0
Oct1 H2O2-HelaGSE14283 181555308 181555341 33 0
Oct1 H2O2-HelaGSE14283 181558074 181558127 53 0
Oct1 HelaGSE14283 181555311 181555341 30 0
Oct1 HelaGSE14283 181558074 181558110 36 0
Oct1 HelaGSE14283 181559939 181559969 30 0
Oct1 HelaGSE14283 181630178 181630208 30 0
Stat6 IL-4-hr1GSE17850 181580435 181580965 530 0
TAF k562GSE8489 181554151 181555134 983 0
TFAP2C MCF7GSE21234 181620806 181621224 418 0
hScc1 BcellGSE12603 181631620 181631990 370 0
hScc1 CdLSGSE12603 181631552 181632023 471 0
hScc1 G2GSE9613 181553171 181554199 1028 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018