AutismKB 2.0

Annotation Detail for SEC23B


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Basic Information Top
Gene Symbol:SEC23B ( CDA-II,CDAII,CDAN2,HEMPAS )
Gene Full Name: Sec23 homolog B (S. cerevisiae)
Band: 20p11.23
Quick LinksEntrez ID:10483; OMIM: 224100,610512; Uniprot ID:SC23B_HUMAN; ENSEMBL ID: ENSG00000101310; HGNC ID: 10702
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
320N6-acetyllysine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
43Phosphothreonine(CDK)HMM predict
43Phosphothreonine(MAPK)HMM predict
228Phosphoserine(CDK)HMM predict
241N-linkedHMM predict
266Phosphothreonine(PKA)HMM predict
338N-linkedHMM predict
343N-linkedHMM predict
367N-linkedHMM predict
372Phosphotyrosine(INSR)HMM predict
380N-linkedHMM predict
492Phosphothreonine(PKC)HMM predict
499Phosphothreonine(PKA)HMM predict
569Phosphoserine(IKK)HMM predict
577Phosphoserine(CK1)HMM predict
596N-linkedHMM predict
597N-linkedHMM predict
598Phosphoserine(CDC2)HMM predict
602Phosphoserine(PKA)HMM predict
603Phosphoserine(CK1)HMM predict
605Phosphotyrosine(EGFR)HMM predict
674Phosphotyrosine(EGFR)HMM predict
674Phosphotyrosine(Syk)HMM predict
725N-linkedHMM predict
727Phosphoserine(ATM)HMM predict
731N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006363
  • Location:chr20 18436187-18490049
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 18435916 18436276 360 92
LIN54 SGSE7516 18435842 18436125 283 204
P300 T30-glioblastomaGSE21026 18435354 18437001 1647 10
hScc1 BcellGSE12603 18435879 18436167 288 165
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 18495432 18496679 1247 6006
GABP HelaGSE8489 18495244 18496654 1410 5900
GABP k562GSE8489 18495244 18496654 1410 5900
H3ac HepG2E 18495244 18496654 1410 5900
Nanog ESGSE20650 18495762 18496235 473 5949
PHF8 293TGSE20725 18495375 18496534 1159 5905
PHF8 HeLaGSE20725 18495622 18496572 950 6048
PHF8 Hs68minusFBSGSE20725 18495346 18496654 1308 5951
PHF8 Hs68plusFBSGSE20725 18495155 18496651 1496 5854
Rb SenescentGSE19898 18496018 18496362 344 6141
TAFII hESGSE17917 18495714 18496263 549 5939
USF1 HepG2E 18495244 18496654 1410 5900
USF2 HepG2E 18495244 18496654 1410 5900
hScc1 BcellGSE12603 18495877 18496128 251 5953
p130 QuiescentGSE19898 18495822 18496450 628 6087
p130 shRbQuiescentGSE19898 18495984 18496390 406 6138
p130 shRbSenescentGSE19898 18495736 18496293 557 5965
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 18435762 18436912 1150 0
Fos K562GSE19551 18435767 18436856 1089 0
H3K4me2 HCT116GSE10453 18437005 18437332 327 0
H3K4me3 colorectalcancer 18436706 18437332 626 0
H3ac HepG2E 18435842 18437332 1490 0
H3ac HepG2E 18437679 18438217 538 0
P300 T0-glioblastomaGSE21026 18435669 18436964 1295 0
PHF8 293TGSE20725 18435629 18437210 1581 0
PHF8 HeLaGSE20725 18435789 18437110 1321 0
TAF HelaGSE8489 18436746 18437332 586 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018