Annotation Detail for SEC23A

View Evidences	View Variants	View Annotations

Basic Information Top

Gene Symbol:	SEC23A ( CLSD,MGC26267 )
Gene Full Name:	Sec23 homolog A (S. cerevisiae)
Band:	14q21.1
Quick Links	Entrez ID:10484; OMIM: 610511; Uniprot ID:SC23A_HUMAN; ENSEMBL ID: ENSG00000100934; HGNC ID: 10701
Relate to Another Database:	SFARIGene; denovo-db

Post Translation Modification

Location(AA)	Modification
308	Phosphothreonine.

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	CD4	GSE12889	38646607	38646864	257	4548
CTCF	CD4	SISSRdata	38646607	38646864	257	4548
H3ac	HepG2	E	38642210	38643119	909	477
H3ac	HepG2	E	38643446	38643659	213	1365
NFkBII	GM12892	GSE19485	38641777	38642804	1027	103
PHF8	293T	GSE20725	38641619	38642785	1166	15
Rb	Growing	GSE19898	38642091	38642304	213	10
Rb	Quiescent	GSE19898	38642250	38642525	275	200
Rb	Senescent	GSE19898	38642043	38642662	619	165
hScc1	CdLS	GSE12603	38643446	38643659	213	1365
p130	Quiescent	GSE19898	38642382	38642591	209	299
p130	Senescent	GSE19898	38641994	38642826	832	223
p130	shRbQuiescent	GSE19898	38642113	38642878	765	308
p130	shRbSenescent	GSE19898	38641984	38642712	728	161

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	CD4	GSE12889	38554371	38554609	238	16384
CTCF	CD4	SISSRdata	38554371	38554609	238	16384
RARA	MCF7	GSE15244	38555297	38556097	800	15177
RARG	MCF7	GSE15244	38555444	38556067	623	15118
USF1	HepG2	E	38564833	38565398	565	5758
USF2	HepG2	E	38562313	38563518	1205	7958

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length
CTCF	G2	GSE9613	38641967	38642243	276
ER	E2-MCF7	GSE14664	38574772	38574805	33
ER	E2-MCF7	GSE14664	38583509	38583541	32
H3K4me3	colorectal	cancer	38641217	38641756	539
H3ac	HepG2	E	38641217	38641859	642
Oct1	H2O2-Hela	GSE14283	38586909	38586940	31
Oct1	H2O2-Hela	GSE14283	38630064	38630109	45
Oct1	Hela	GSE14283	38586911	38586940	29
Oct1	Hela	GSE14283	38630064	38630110	46
PHF8	HeLa	GSE20725	38641477	38642741	1264
RARA	MCF7	GSE15244	38589035	38589832	797
USF2	HepG2	E	38641217	38641679	462
p130	Quiescent	GSE19898	38641475	38641827	352
p130	Quiescent	GSE19898	38641991	38642271	280
p130	shRbQuiescent	GSE19898	38641334	38641828	494

Validated miRNA targets

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-let-7b	hsa-let-7b	22	18668040
hsa-let-7b*	hsa-let-7b	22	18668040
hsa-miR-1	hsa-mir-1-2	18	18668040
hsa-miR-1	hsa-mir-1-1	20	18668040
hsa-miR-155	hsa-mir-155	21	18668040
hsa-miR-155*	hsa-mir-155	21	18668040
hsa-miR-16	hsa-mir-16-1	13	18668040
hsa-miR-16	hsa-mir-16-2	3	18668040
hsa-miR-30a	hsa-mir-30a	6	18668040
hsa-miR-30a*	hsa-mir-30a	6	18668040
hsa-miR-30b	hsa-mir-30b	8	18668040
hsa-miR-30b*	hsa-mir-30b	8	18668040
hsa-miR-30c	hsa-mir-30c-2	6	18668040
hsa-miR-30c	hsa-mir-30c-1	1	18668040
hsa-miR-30c-1*	hsa-mir-30c-1	1	18668040
hsa-miR-30c-2*	hsa-mir-30c-2	6	18668040
hsa-miR-30d	hsa-mir-30d	8	18668040
hsa-miR-30d*	hsa-mir-30d	8	18668040
hsa-miR-30e	hsa-mir-30e	1	18668040
hsa-miR-30e*	hsa-mir-30e	1	18668040

ID in Tarbase	Data Type	Support Type	miRNA	Gene	Direct Support	Publication
1274	Unknown	pSILAC	miR-30	SEC23A	down 50-25%	18668040
Ensembl	Protein Type	Differentially expressed in	Pathology or Event	Mis Regulation	Gene Expression	Tumour Involvement
ENSG00000100934		n_a	n_a	n_a	"squamous cell, lymphocyte, muscle cell"	"benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"

Cis-Nats regulation

Simple Query:

Paper Collected: 6/30/2018

Last Update: 8/26/2018