AutismKB 2.0

Annotation Detail for STK25


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Basic Information Top
Gene Symbol:STK25 ( DKFZp686J1430,SOK1,YSK1 )
Gene Full Name: serine/threonine kinase 25
Band: 2q37.3
Quick LinksEntrez ID:10494; OMIM: 602255; Uniprot ID:STK25_HUMAN; ENSEMBL ID: ENSG00000115694; HGNC ID: 11404
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
168Phosphothreonine.
174Phosphothreonine; by autocatalysis.
342Phosphoserine.
Location(AA) Modifications Resource
174Phosphothreonine (by autocatalysis).Swiss-Prot 53.0
Location(AA) Modification Resource
40N-linkedHMM predict
75Phosphoserine(CDC2)HMM predict
75Phosphoserine(IKK)HMM predict
130Phosphotyrosine(Jak)HMM predict
299Phosphoserine(CK2)HMM predict
301Phosphoserine(CK2)HMM predict
301Phosphoserine(CK1)HMM predict
301Phosphoserine(ATM)HMM predict
304Phosphoserine(CK1)HMM predict
328Phosphoserine(CDK)HMM predict
342Phosphoserine(ATM)HMM predict
355Phosphoserine(IKK)HMM predict
412ValineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006374
  • Location:chr2 242083105-242096706
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 242097056 242097480 424 562
ETS1 JurkatGSE17954 242096466 242097478 1012 266
P300 T30-glioblastomaGSE21026 242096480 242097484 1004 276
PHF8 Hs68plusFBSGSE20725 242096013 242097695 1682 148
Rb GrowingGSE19898 242096751 242097013 262 176
Rb GrowingGSE19898 242097126 242097288 162 501
USF1 HepG2E 242097235 242097733 498 778
VDR GM10861-UnstimGSE22484 242096153 242097758 1605 249
hScc1 BcellGSE12603 242096583 242096950 367 60
p130 QuiescentGSE19898 242096766 242097302 536 328
p130 shRbSenescentGSE19898 242096795 242097382 587 382
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 242083863 242084178 315 0
CTCF G2GSE9613 242084578 242086288 1710 0
CTCF G2GSE9613 242087159 242088291 1132 0
CTCF G2GSE9613 242088753 242089475 722 0
CTCF G2GSE9613 242092381 242092609 228 0
CTCF G2GSE9613 242093682 242093926 244 0
CTCF G2GSE9613 242095399 242096262 863 0
CTCF G2GSE9613 242096583 242096717 134 0
H3ac HepG2E 242094887 242095863 976 0
Rb QuiescentGSE19898 242096148 242096265 117 0
Rb QuiescentGSE19898 242096479 242096847 368 0
Rb SenescentGSE19898 242095896 242096202 306 0
hScc1 BcellGSE12603 242084214 242085163 949 0
hScc1 BcellGSE12603 242086068 242086390 322 0
hScc1 BcellGSE12603 242087095 242087641 546 0
hScc1 BcellGSE12603 242095475 242096262 787 0
hScc1 G2GSE9613 242095220 242096082 862 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018