AutismKB 2.0

Annotation Detail for SEMA6C


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Basic Information Top
Gene Symbol:SEMA6C ( SEMAY,m-SemaY,m-SemaY2 )
Gene Full Name: sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
Band: 1q21.3
Quick LinksEntrez ID:10500; OMIM: 609294; Uniprot ID:SEM6C_HUMAN; ENSEMBL ID: ENSG00000143434; HGNC ID: 10740
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
70N-linked (GlcNAc...) (Potential).
286N-linked (GlcNAc...) (Potential).
437N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
70N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
286N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
437N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
70N-linkedHMM predict
286N-linkedHMM predict
325Phosphoserine(IKK)HMM predict
358Phosphothreonine(MAPK)HMM predict
367Phosphoserine(CDC2)HMM predict
367Phosphoserine(CDK)HMM predict
367O-linkedHMM predict
372Phosphoserine(IKK)HMM predict
437N-linkedHMM predict
487Phosphothreonine(PKC)HMM predict
577Phosphoserine(ATM)HMM predict
577Phosphoserine(IKK)HMM predict
600Phosphoserine(ATM)HMM predict
600Phosphoserine(IKK)HMM predict
668O-linkedHMM predict
681O-linkedHMM predict
682O-linkedHMM predict
700Phosphothreonine(MAPK)HMM predict
700Phosphothreonine(CDK)HMM predict
700O-linkedHMM predict
736MethylarginineHMM predict
791Phosphothreonine(PKC)HMM predict
792O-linkedHMM predict
792O-linkedHMM predict
808Phosphoserine(CDC2)HMM predict
808O-linkedHMM predict
830Phosphoserine(PKA)HMM predict
855O-linkedHMM predict
855Phosphoserine(CDK)HMM predict
893MethylarginineHMM predict
917O-linkedHMM predict
928PhenylalanineHMM predict
929PhenylalanineHMM predict
930PhenylalanineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_030913
  • Location:chr1 149370788-149385727
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 149385793 149386130 337 234
H3ac HepG2E 149386355 149387016 661 958
P300 T30-glioblastomaGSE21026 149385508 149386460 952 257
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 149365016 149365591 575 5485
Myc hESGSE17917 149370376 149370724 348 239
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 149372057 149372965 908 0
CTCF G2GSE9613 149374229 149374488 259 0
hScc1 BcellGSE12603 149372413 149372892 479 0
hScc1 BcellGSE12603 149374229 149374528 299 0
hScc1 BcellGSE12603 149385217 149385941 724 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018