AutismKB 2.0

Annotation Detail for IPO8


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Basic Information Top
Gene Symbol:IPO8 ( FLJ21954,FLJ26580,RANBP8 )
Gene Full Name: importin 8
Band: 12p11.21
Quick LinksEntrez ID:10526; OMIM: 605600; Uniprot ID:IPO8_HUMAN; ENSEMBL ID: ENSG00000133704; HGNC ID: 9853
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
389Phosphoserine.
902Phosphoserine.
903Phosphoserine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
137Phosphotyrosine(Jak)HMM predict
145Phosphoserine(IKK)HMM predict
195Phosphotyrosine(Syk)HMM predict
223N-linkedHMM predict
281N-linkedHMM predict
374Phosphotyrosine(SRC)HMM predict
376SulfotyrosineHMM predict
376Phosphotyrosine(INSR)HMM predict
391O-linkedHMM predict
392O-linkedHMM predict
505Phosphoserine(PKG)HMM predict
535Phosphotyrosine(Jak)HMM predict
535Phosphotyrosine(INSR)HMM predict
570SulfotyrosineHMM predict
598Phosphotyrosine(EGFR)HMM predict
598Phosphotyrosine(SRC)HMM predict
598Phosphotyrosine(Jak)HMM predict
598Phosphotyrosine(Syk)HMM predict
598SulfotyrosineHMM predict
598Phosphotyrosine(INSR)HMM predict
666PhosphoserineHMM predict
700Phosphotyrosine(INSR)HMM predict
722S-palmitoylHMM predict
823N-linkedHMM predict
902Phosphoserine(CK2)HMM predict
902Phosphoserine(CK1)HMM predict
902Phosphoserine(CK2)HMM predict
903Phosphoserine(CK2)HMM predict
903Phosphoserine(CK1)HMM predict
903Phosphoserine(ATM)HMM predict
909N-linkedHMM predict
954Phosphoserine(CK2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006390
  • Location:chr12 30673189-30740017
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 30739554 30740690 1136 105
P300 T0-glioblastomaGSE21026 30739644 30740726 1082 168
PHF8 Hs68plusFBSGSE20725 30739709 30740769 1060 222
TFAP2C MCF7GSE21234 30739988 30740492 504 223
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 H2O2-HelaGSE14283 30662999 30663048 49 10166
Oct1 HelaGSE14283 30662998 30663049 51 10166
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 30739214 30740143 929 0
ER MCF7GSE19013 30719690 30720207 517 0
H3K4me3 colorectalcancer 30738288 30739714 1426 0
H3ac HepG2E 30738156 30739596 1440 0
Myc hESGSE17917 30739614 30739809 195 0
Oct1 H2O2-HelaGSE14283 30720560 30720590 30 0
Oct1 HelaGSE14283 30720560 30720591 31 0
P300 T30-glioblastomaGSE21026 30739248 30740781 1533 0
STAT1 HeLaGSE12783 30738766 30741172 2406 0
TAF HelaGSE8489 30738647 30739495 848 0
hScc1 BcellGSE12603 30739714 30740143 429 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018