AutismKB 2.0

Annotation Detail for TACC2


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Basic Information Top
Gene Symbol:TACC2 ( AZU-1,ECTACC )
Gene Full Name: transforming, acidic coiled-coil containing protein 2
Band: 10q26.13
Quick LinksEntrez ID:10579; OMIM: 605302; Uniprot ID:TACC2_HUMAN; ENSEMBL ID: ENSG00000138162; HGNC ID: 11523
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
197Phosphoserine.
201Phosphoserine.
493Phosphoserine.
571Phosphoserine.
575Phosphoserine.
758Phosphoserine.
962Phosphoserine.
1025Phosphoserine.
1267Phosphoserine.
1313Phosphoserine.
1426Phosphothreonine.
1562Phosphoserine.
1946Phosphoserine (By similarity).
1949Phosphoserine (By similarity).
2072Phosphoserine.
2073Phosphothreonine.
2226Phosphoserine.
2246Phosphothreonine.
2256Phosphoserine.
2317Phosphoserine.
2321Phosphoserine.
2359Phosphoserine.
2389Phosphoserine.
2390Phosphoserine.
2392Phosphoserine.
2394Phosphoserine.
2403Phosphoserine.
2512Phosphoserine.
2884N6-acetyllysine.
Location(AA) Modifications Resource
1946Phosphoserine (By similarity).Swiss-Prot 53.0
1949Phosphoserine (By similarity).Swiss-Prot 53.0
2256Phosphoserine.Swiss-Prot 53.0
2317Phosphoserine (By similarity).Swiss-Prot 53.0
2512Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
10N-linkedHMM predict
18Phosphothreonine(CDC2)HMM predict
18Phosphothreonine(MAPK)HMM predict
38Phosphothreonine(MAPK)HMM predict
41Phosphoserine(CDC2)HMM predict
65O-linkedHMM predict
67Phosphoserine(IKK)HMM predict
74Phosphoserine(CDC2)HMM predict
74Phosphoserine(MAPK)HMM predict
93O-linkedHMM predict
97O-linkedHMM predict
97Phosphoserine(CDC2)HMM predict
97Phosphoserine(ATM)HMM predict
101Phosphoserine(ATM)HMM predict
124Phosphoserine(MAPK)HMM predict
137Phosphoserine(CDC2)HMM predict
137PhosphoserineHMM predict
137Phosphoserine(MAPK)HMM predict
164Phosphotyrosine(SRC)HMM predict
164Phosphotyrosine(Syk)HMM predict
201PhosphoserineHMM predict
249O-linkedHMM predict
249Phosphothreonine(CDC2)HMM predict
249Phosphothreonine(MAPK)HMM predict
269Phosphoserine(CDC2)HMM predict
269Phosphoserine(CDK)HMM predict
310S-palmitoylHMM predict
317Phosphoserine(IKK)HMM predict
332Phosphoserine(IKK)HMM predict
404Phosphoserine(CDC2)HMM predict
404Phosphoserine(MAPK)HMM predict
404Phosphoserine(ATM)HMM predict
408O-linkedHMM predict
411Phosphothreonine(MAPK)HMM predict
411Phosphothreonine(CDK)HMM predict
444Phosphoserine(PKG)HMM predict
446Phosphoserine(IKK)HMM predict
473Phosphoserine(CAMK2)HMM predict
477Phosphoserine(CK1)HMM predict
493Phosphoserine(CDC2)HMM predict
493Phosphoserine(CDK)HMM predict
540Phosphoserine(CK2)HMM predict
542O-linkedHMM predict
559O-linkedHMM predict
561Phosphoserine(MAPK)HMM predict
571Phosphoserine(CDC2)HMM predict
571Phosphoserine(ATM)HMM predict
575Phosphoserine(CDC2)HMM predict
616Phosphoserine(CK1)HMM predict
619Phosphoserine(CK2)HMM predict
620Phosphoserine(CK2)HMM predict
630O-linkedHMM predict
649Phosphoserine(ATM)HMM predict
726Phosphothreonine(MAPK)HMM predict
833Phosphoserine(ATM)HMM predict
859PhosphoserineHMM predict
903Phosphoserine(ATM)HMM predict
911O-linkedHMM predict
913O-linkedHMM predict
913O-linkedHMM predict
913Phosphothreonine(MAPK)HMM predict
913Phosphothreonine(CDK)HMM predict
915Phosphothreonine(MAPK)HMM predict
917Phosphoserine(CDC2)HMM predict
919O-linkedHMM predict
959O-linkedHMM predict
991N-linkedHMM predict
1005Phosphoserine(CK1)HMM predict
1005Phosphoserine(CK2)HMM predict
1005Phosphoserine(ATM)HMM predict
1067O-linkedHMM predict
1067Phosphoserine(MAPK)HMM predict
1071O-linkedHMM predict
1071Phosphothreonine(MAPK)HMM predict
1175O-linkedHMM predict
1225Phosphoserine(ATM)HMM predict
1235Phosphothreonine(MAPK)HMM predict
1237Phosphotyrosine(Jak)HMM predict
1237Phosphotyrosine(Syk)HMM predict
1310O-linkedHMM predict
1313Phosphoserine(CDC2)HMM predict
1319O-linkedHMM predict
1342Phosphothreonine(PKC)HMM predict
1342Phosphothreonine(CK2)HMM predict
1358Phosphoserine(PKG)HMM predict
1381Phosphoserine(ATM)HMM predict
1426Phosphothreonine(MAPK)HMM predict
1461O-linkedHMM predict
1546Phosphotyrosine(EGFR)HMM predict
1546Phosphotyrosine(SRC)HMM predict
1562Phosphoserine(CDC2)HMM predict
1562Phosphoserine(CDK)HMM predict
1603Phosphothreonine(PKA)HMM predict
1631O-linkedHMM predict
1635Phosphoserine(CDC2)HMM predict
1648Phosphoserine(CK1)HMM predict
1677N-linkedHMM predict
1680O-linkedHMM predict
1691Phosphothreonine(MAPK)HMM predict
1768Phosphoserine(CDC2)HMM predict
1796Phosphoserine(CDC2)HMM predict
1878O-linkedHMM predict
1902Phosphoserine(CDC2)HMM predict
1920O-linkedHMM predict
1920Phosphoserine(MAPK)HMM predict
1932Phosphoserine(IKK)HMM predict
1935Phosphoserine(IKK)HMM predict
1947Phosphoserine(CK1)HMM predict
1947Phosphoserine(CK2)HMM predict
1955Phosphothreonine(CDC2)HMM predict
1955Phosphothreonine(MAPK)HMM predict
1958O-linkedHMM predict
1960Phosphothreonine(CDC2)HMM predict
1960Phosphothreonine(CDK)HMM predict
1982O-linkedHMM predict
2007Phosphoserine(CK1)HMM predict
2007Phosphoserine(IKK)HMM predict
2011Phosphoserine(CDC2)HMM predict
2017O-linkedHMM predict
2068Phosphothreonine(PKC)HMM predict
2072Phosphoserine(PKA)HMM predict
2072Phosphoserine(PKG)HMM predict
2072Phosphoserine(PKB)HMM predict
2073Phosphothreonine(PKA)HMM predict
2075Phosphoserine(IKK)HMM predict
2088Phosphoserine(CK1)HMM predict
2088Phosphoserine(IKK)HMM predict
2100Phosphoserine(ATM)HMM predict
2113Phosphotyrosine(Jak)HMM predict
2114O-linkedHMM predict
2115Phosphothreonine(PKC)HMM predict
2119O-linkedHMM predict
2121O-linkedHMM predict
2121Phosphoserine(CK2)HMM predict
2123Phosphothreonine(PKC)HMM predict
2123Phosphothreonine(CDK)HMM predict
2134Phosphoserine(PKC)HMM predict
2140Phosphothreonine(PKC)HMM predict
2147Phosphothreonine(MAPK)HMM predict
2209Phosphoserine(CK1)HMM predict
2246Phosphothreonine(MAPK)HMM predict
2246PhosphothreonineHMM predict
2275Phosphoserine(IKK)HMM predict
2317Phosphoserine(CDC2)HMM predict
2317PhosphoserineHMM predict
2321Phosphoserine(CDC2)HMM predict
2321Phosphoserine(CDK)HMM predict
2321Phosphoserine(ATM)HMM predict
2321Phosphoserine(IKK)HMM predict
2387O-linkedHMM predict
2387Phosphothreonine(CDK)HMM predict
2389O-linkedHMM predict
2390Phosphoserine(CDC2)HMM predict
2424Phosphothreonine(MAPK)HMM predict
2424Phosphothreonine(CDK)HMM predict
2436Phosphoserine(CDC2)HMM predict
2436Phosphoserine(CDK)HMM predict
2440Phosphoserine(CDC2)HMM predict
2443Phosphoserine(ATM)HMM predict
2447O-linkedHMM predict
2447Phosphoserine(ATM)HMM predict
2447Phosphoserine(IKK)HMM predict
2451O-linkedHMM predict
2451O-linkedHMM predict
2451Phosphothreonine(MAPK)HMM predict
2455O-linkedHMM predict
2458Phosphothreonine(MAPK)HMM predict
2463O-linkedHMM predict
2495Phosphotyrosine(EGFR)HMM predict
2495Phosphotyrosine(Syk)HMM predict
2506N-linkedHMM predict
2512Phosphoserine(CDC2)HMM predict
2512Phosphoserine(CDK)HMM predict
2519Phosphotyrosine(INSR)HMM predict
2519SulfotyrosineHMM predict
2522PhosphoserineHMM predict
2554Phosphoserine(ATM)HMM predict
2557Phosphoserine(CDK)HMM predict
2557PhosphoserineHMM predict
2562Phosphoserine(CDC2)HMM predict
2567O-linkedHMM predict
2567Phosphoserine(PKA)HMM predict
2567Phosphoserine(IKK)HMM predict
2569Phosphoserine(CDK)HMM predict
2661Phosphotyrosine(INSR)HMM predict
2661Phosphotyrosine(Jak)HMM predict
2805Phosphoserine(CK1)HMM predict
2874Phosphotyrosine(EGFR)HMM predict
2874Phosphotyrosine(SRC)HMM predict
2874Phosphotyrosine(Syk)HMM predict
2909Phosphoserine(CAMK2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006997
  • Location:chr10 123913094-124004044
  • strand:+
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
p130 shRbSenescentGSE19898 124007803 124007967 164 3841
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 123951472 123952372 900 0
ER Breast-CancerGSE22609 123932726 123933338 612 0
P300 T30-glioblastomaGSE21026 123951550 123952285 735 0
TFAP2C MCF7GSE21234 123923368 123923949 581 0
TFAP2C MCF7GSE21234 123974608 123974873 265 0
hScc1 BcellGSE12603 123967763 123967938 175 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
3779 mRNA TACC2 chr10 123738678 124004045 3450 EST chr10 123763395 123766845 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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