AutismKB 2.0

Annotation Detail for ERN2


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Basic Information Top
Gene Symbol:ERN2 ( IRE1b )
Gene Full Name: endoplasmic reticulum to nucleus signaling 2
Band: 16p12.2
Quick LinksEntrez ID:10595; OMIM: 604034; Uniprot ID:ERN2_HUMAN; ENSEMBL ID: ENSG00000134398; HGNC ID: 16942
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
29Phosphoserine(ATM)HMM predict
75Phosphotyrosine(Abl)HMM predict
119Phosphoserine(CK1)HMM predict
148O-linkedHMM predict
179N-linkedHMM predict
186Phosphoserine(PKG)HMM predict
268Phosphoserine(ATM)HMM predict
273O-linkedHMM predict
339Phosphoserine(IKK)HMM predict
379Phosphothreonine(CDC2)HMM predict
382Phosphoserine(CK2)HMM predict
404Phosphoserine(CK1)HMM predict
475Phosphoserine(ATM)HMM predict
480Phosphoserine(CK1)HMM predict
486Phosphothreonine(PKC)HMM predict
495Phosphoserine(IKK)HMM predict
495Phosphoserine(CDK)HMM predict
495Phosphoserine(CAMK2)HMM predict
495Phosphoserine(CDC2)HMM predict
536MethylarginineHMM predict
596Phosphoserine(PKG)HMM predict
698Phosphoserine(CDK)HMM predict
698Phosphoserine(MAPK)HMM predict
698Phosphoserine(CDC2)HMM predict
728Phosphotyrosine(EGFR)HMM predict
908Phosphotyrosine(Syk)HMM predict
919S-farnesylHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_033266
  • Location:chr16 23609197-23632321
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Myc K562GSE19551 23646411 23647058 647 14413
P300 T30-glioblastomaGSE21026 23646585 23647172 587 14557
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 23609589 23610029 440 0
CTCF G2GSE9613 23623452 23623857 405 0
CTCF G2GSE9613 23631779 23632304 525 0
NRSF JurkatGSE13047 23619801 23620288 487 0
NRSF-mono JurkatQuESTdata 23619843 23620287 444 0
NRSF-poly JurkatQuESTdata 23619828 23620177 349 0
Oct4 hESGSE17917 23613760 23614066 306 0
hScc1 BcellGSE12603 23609849 23610290 441 0
hScc1 BcellGSE12603 23631828 23632116 288 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018