AutismKB 2.0

Annotation Detail for CCT8


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:CCT8 ( C21orf112,Cctq,D21S246,KIAA0002,PRED71 )
Gene Full Name: chaperonin containing TCP1, subunit 8 (theta)
Band: 21q21.3
Quick LinksEntrez ID:10694; OMIM: NA; Uniprot ID:TCPQ_HUMAN; ENSEMBL ID: ENSG00000156261; HGNC ID: 1623
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
7N6-acetyllysine.
20N6-acetyllysine.
23Phosphoserine.
30Phosphotyrosine.
227Phosphothreonine.
232Phosphothreonine.
233Phosphoserine.
318N6-acetyllysine.
400N6-acetyllysine.
466N6-acetyllysine.
505Phosphotyrosine.
Location(AA) Modifications Resource
2N-acetylalanine.Swiss-Prot 53.0
20N6-acetyllysine.Swiss-Prot 53.0
29PhosphotyrosinePhospho.ELM 6.0
505Phosphotyrosine.Swiss-Prot 53.0
Location(AA) Modification Resource
30Phosphotyrosine(SRC)HMM predict
162Phosphoserine(CK1)HMM predict
403Phosphothreonine(PKC)HMM predict
517Phosphothreonine(PKC)HMM predict
537SerineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006585
  • Location:chr21 29350520-29367880
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
PHF8 293TGSE20725 29367240 29368704 1464 92
PHF8 HeLaGSE20725 29367225 29368650 1425 57
p130 SenescentGSE19898 29367478 29368376 898 47
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 29367133 29368438 1305 0
H3K4me3 colorectalcancer 29366656 29367493 837 0
H3ac HepG2E 29365881 29367722 1841 0
PHF8 Hs68minusFBSGSE20725 29367037 29368392 1355 0
TAF k562GSE8489 29366329 29368318 1989 0
hScc1 BcellGSE12603 29367347 29367903 556 0
p130 shRbSenescentGSE19898 29367630 29368012 382 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018