AutismKB 2.0

Annotation Detail for IQGAP2


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Basic Information Top
Gene Symbol:IQGAP2 ( - )
Gene Full Name: IQ motif containing GTPase activating protein 2
Band: 5q13.3
Quick LinksEntrez ID:10788; OMIM: 605401; Uniprot ID:IQGA2_HUMAN; ENSEMBL ID: ENSG00000145703; HGNC ID: 6111
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
16Phosphoserine.
1389Phosphoserine (By similarity).
1471N6-acetyllysine.
1474N6-acetyllysine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
24Phosphoserine(CK2)HMM predict
93Phosphotyrosine(Syk)HMM predict
93Phosphotyrosine(INSR)HMM predict
208Phosphoserine(CK1)HMM predict
278Phosphoserine(CK1)HMM predict
285Phosphotyrosine(EGFR)HMM predict
285Phosphotyrosine(Syk)HMM predict
285SulfotyrosineHMM predict
396Phosphoserine(CDC2)HMM predict
425Phosphoserine(ATM)HMM predict
482N-linkedHMM predict
563Phosphoserine(IKK)HMM predict
566Phosphoserine(IKK)HMM predict
596Phosphoserine(CK1)HMM predict
611SulfotyrosineHMM predict
612SulfotyrosineHMM predict
612Phosphotyrosine(Syk)HMM predict
613SulfotyrosineHMM predict
621Phosphoserine(IKK)HMM predict
624O-linkedHMM predict
636Phosphothreonine(PKC)HMM predict
735Phosphothreonine(PKC)HMM predict
864N-linkedHMM predict
865N-linkedHMM predict
868N-linkedHMM predict
881Phosphothreonine(PKA)HMM predict
881Phosphothreonine(PKC)HMM predict
881Phosphothreonine(PKG)HMM predict
881Phosphothreonine(PKA)HMM predict
961N-linkedHMM predict
980Phosphothreonine(PKC)HMM predict
1055Phosphothreonine(PKA)HMM predict
1092PhosphothreonineHMM predict
1172Phosphotyrosine(Syk)HMM predict
1178Phosphotyrosine(Jak)HMM predict
1209Phosphotyrosine(INSR)HMM predict
1271Phosphoserine(ATM)HMM predict
1274Phosphoserine(CK1)HMM predict
1349Phosphothreonine(CDC2)HMM predict
1356Phosphoserine(ATM)HMM predict
1393Phosphotyrosine(Syk)HMM predict
1410Phosphotyrosine(EGFR)HMM predict
1441Phosphotyrosine(Syk)HMM predict
1442SulfotyrosineHMM predict
1456MethyllysineHMM predict
1458Phosphothreonine(PKC)HMM predict
1458Phosphothreonine(PKA)HMM predict
1505N-linkedHMM predict
1545Phosphotyrosine(Syk)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006633
  • Location:chr5 75734904-76039710
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 75718027 75718264 237 16759
ER MCF7GSE19013 75721356 75721848 492 13303
Oct1 H2O2-HelaGSE14283 75732610 75732638 28 2281
RARA MCF7GSE15244 75719494 75720129 635 15093
Sox2 hESGSE18292 75723927 75724341 414 10771
TFAP2C MCF7GSE21234 75717908 75718540 632 16681
hScc1 BcellGSE12603 75734263 75735518 1255 14
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
P300 T30-glioblastomaGSE21026 76042137 76043621 1484 3169
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 75733002 75737593 4591 0
CBP T30-glioblastomaGSE21026 76020613 76021794 1181 0
CTCF CD4GSE12889 75875863 75876282 419 0
CTCF CD4GSE12889 75915144 75915408 264 0
CTCF CD4GSE12889 75973217 75973395 178 0
CTCF CD4SISSRdata 75875863 75876282 419 0
CTCF CD4SISSRdata 75915144 75915408 264 0
CTCF CD4SISSRdata 75973217 75973395 178 0
CTCF G2GSE9613 75736133 75736359 226 0
CTCF G2GSE9613 75759462 75759718 256 0
CTCF G2GSE9613 75803678 75803927 249 0
CTCF G2GSE9613 75807787 75807966 179 0
CTCF G2GSE9613 75814992 75815314 322 0
CTCF G2GSE9613 75836420 75836708 288 0
CTCF G2GSE9613 75841967 75842409 442 0
CTCF G2GSE9613 75869951 75870090 139 0
CTCF G2GSE9613 75875772 75876120 348 0
CTCF G2GSE9613 75932951 75934334 1383 0
ER Fulvestrant-MCF7GSE14664 75987594 75987628 34 0
FOXA1 MCF7GSE15244 75741786 75742980 1194 0
FOXA1 MCF7GSE15244 76022726 76022905 179 0
Gata2 K562GSE18868 75989436 75990324 888 0
Myc K562GSE19551 75989395 75989892 497 0
Nanog hESGSE18292 75830990 75831510 520 0
Oct1 H2O2-HelaGSE14283 75879945 75879975 30 0
Oct1 H2O2-HelaGSE14283 75883240 75883273 33 0
Oct1 H2O2-HelaGSE14283 75909078 75909127 49 0
Oct1 H2O2-HelaGSE14283 75924108 75924163 55 0
Oct1 H2O2-HelaGSE14283 75986498 75986525 27 0
Oct1 HelaGSE14283 75812033 75812064 31 0
Oct1 HelaGSE14283 75830734 75830772 38 0
Oct1 HelaGSE14283 75879927 75879976 49 0
Oct1 HelaGSE14283 75883240 75883272 32 0
Oct1 HelaGSE14283 75909085 75909126 41 0
Oct1 HelaGSE14283 75924113 75924162 49 0
Oct1 HelaGSE14283 75986954 75986992 38 0
Oct1 HelaGSE14283 75987590 75987657 67 0
Oct1 HelaGSE14283 75994245 75994275 30 0
P300 T0-glioblastomaGSE21026 75742376 75743274 898 0
P300 T30-glioblastomaGSE21026 75832455 75833214 759 0
P300 T30-glioblastomaGSE21026 76020139 76022241 2102 0
Sox2 hESGSE18292 75830998 75831483 485 0
USF1 HepG2E 75735302 75736500 1198 0
USF2 HepG2E 75735841 75736429 588 0
hScc1 BcellGSE12603 75736252 75736789 537 0
hScc1 BcellGSE12603 75875666 75876363 697 0
hScc1 BcellGSE12603 75932985 75933610 625 0
hScc1 BcellGSE12603 75973189 75973564 375 0
hScc1 CdLSGSE12603 75733977 75735985 2008 0
hScc1 CdLSGSE12603 75875560 75876437 877 0
hScc1 CdLSGSE12603 75933063 75933747 684 0
hScc1 CdLSGSE12603 75973008 75973636 628 0
hScc1 G2GSE9613 75875701 75876232 531 0
hScc1 G2GSE9613 75932756 75934397 1641 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
21135 mRNA IQGAP2 chr5 75734904 76039711 7933 mRNA F2RL2 chr5 75947063 75954996 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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