AutismKB 2.0

Annotation Detail for SEC24A


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Basic Information Top
Gene Symbol:SEC24A ( - )
Gene Full Name: SEC24 family, member A (S. cerevisiae)
Band: 5q31.1
Quick LinksEntrez ID:10802; OMIM: 607183; Uniprot ID:SC24A_HUMAN; ENSEMBL ID: ENSG00000113615; HGNC ID: 10703
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
47N-linkedHMM predict
64Phosphoserine(ATM)HMM predict
70Phosphothreonine(PKC)HMM predict
78O-linkedHMM predict
82Phosphothreonine(MAPK)HMM predict
87Phosphoserine(IKK)HMM predict
104Phosphothreonine(MAPK)HMM predict
104O-linkedHMM predict
104O-linkedHMM predict
108O-linkedHMM predict
132Phosphoserine(IKK)HMM predict
142Phosphoserine(IKK)HMM predict
142Phosphoserine(CK1)HMM predict
142Phosphoserine(PKG)HMM predict
145O-linkedHMM predict
149N-linkedHMM predict
155N-linkedHMM predict
210Phosphothreonine(MAPK)HMM predict
239N-linkedHMM predict
248Phosphotyrosine(EGFR)HMM predict
279O-linkedHMM predict
286N-linkedHMM predict
287O-linkedHMM predict
288O-linkedHMM predict
293O-linkedHMM predict
348Phosphothreonine(CDK)HMM predict
470N-linkedHMM predict
506Phosphotyrosine(Jak)HMM predict
513Phosphoserine(IKK)HMM predict
546Phosphoserine(IKK)HMM predict
548Phosphoserine(ATM)HMM predict
548Phosphoserine(CK1)HMM predict
548Phosphoserine(IKK)HMM predict
658Phosphotyrosine(Syk)HMM predict
725Phosphothreonine(PKC)HMM predict
770Phosphotyrosine(Syk)HMM predict
775Phosphoserine(IKK)HMM predict
779Phosphoserine(CK1)HMM predict
779Phosphoserine(IKK)HMM predict
840Phosphoserine(IKK)HMM predict
938Phosphoserine(CK1)HMM predict
944N-linkedHMM predict
984N-linkedHMM predict
988N-linkedHMM predict
1014Phosphothreonine(MAPK)HMM predict
1076ValineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_021982
  • Location:chr5 134012377-134091498
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 134011579 134012783 1204 197
H3K4me2 HCT116GSE10453 134011624 134012111 487 510
H3K4me3 colorectalcancer 134011663 134012111 448 491
H3ac HepG2E 134011354 134012147 793 627
Oct4 hESGSE17917 134012200 134012421 221 67
TAF HelaGSE8489 134011354 134012307 953 547
TAF k562GSE8489 134011354 134012266 912 568
USF1 HepG2E 134011465 134012111 646 590
hScc1 BcellGSE12603 134012111 134012507 396 69
p130 QuiescentGSE19898 134011860 134012340 480 278
p130 SenescentGSE19898 134011701 134012280 579 387
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 134012147 134012821 674 0
GABP k562GSE8489 134011354 134013790 2436 0
H3K4me3 colorectalcancer 134012744 134014101 1357 0
H3ac HepG2E 134012701 134013447 746 0
Oct1 H2O2-HelaGSE14283 134018970 134019011 41 0
Oct1 H2O2-HelaGSE14283 134036096 134036130 34 0
Oct1 HelaGSE14283 134036096 134036134 38 0
Oct1 HelaGSE14283 134038052 134038086 34 0
Oct1 HelaGSE14283 134080030 134080057 27 0
STAT1 HeLaGSE12782 134021803 134022838 1035 0
STAT1 HeLaGSE12783 134021837 134022838 1001 0
STAT1 IFNSISSRdata 134021780 134022654 874 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7b hsa-let-7b 22 18668040
hsa-let-7b* hsa-let-7b 22 18668040
hsa-miR-1 hsa-mir-1-2 18 18668040
hsa-miR-1 hsa-mir-1-1 20 18668040
hsa-miR-155 hsa-mir-155 21 18668040
hsa-miR-155* hsa-mir-155 21 18668040
hsa-miR-16 hsa-mir-16-1 13 18668040
hsa-miR-16 hsa-mir-16-2 3 18668040
hsa-miR-30a hsa-mir-30a 6 18668040
hsa-miR-30a* hsa-mir-30a 6 18668040
hsa-miR-30b hsa-mir-30b 8 18668040
hsa-miR-30b* hsa-mir-30b 8 18668040
hsa-miR-30c hsa-mir-30c-2 6 18668040
hsa-miR-30c hsa-mir-30c-1 1 18668040
hsa-miR-30c-1* hsa-mir-30c-1 1 18668040
hsa-miR-30c-2* hsa-mir-30c-2 6 18668040
hsa-miR-30d hsa-mir-30d 8 18668040
hsa-miR-30d* hsa-mir-30d 8 18668040
hsa-miR-30e hsa-mir-30e 1 18668040
hsa-miR-30e* hsa-mir-30e 1 18668040
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
1092 Unknown pSILAC miR-16 SEC24A down 50-25% 18668040
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000113615 n_a n_a n_a "leukocyte, lymphocyte, muscle cell" "benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
21479 mRNA SEC24A chr5 134012412 134057286 350 mRNA SARA2 chr5 133957913 134012860Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018